2-CHLORO-5-HYDROXYBENZALDEHYDE
- CAS No.
- 7310-94-3
- Chemical Name:
- 2-CHLORO-5-HYDROXYBENZALDEHYDE
- Synonyms
- 2-CHLORO-5-HYDROXYBENZALDEHYDE;Benzaldehyde, 2-chloro-5-hydroxy-
- CBNumber:
- CB6487162
- Molecular Formula:
- C7H5ClO2
- Molecular Weight:
- 156.57
- MDL Number:
- MFCD07783652
- MOL File:
- Mol file
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Chloro-5-hydroxybenzaldehyde | FC67157 | 1g | $217.69 |
| 2-Chloro-5-hydroxybenzaldehyde | FC67157 | 2g | $290.24 |
| 2-Chloro-5-hydroxybenzaldehyde | FC67157 | 5g | $544.2 |
| 2-Chloro-5-hydroxybenzaldehyde | FC67157 | 10g | $997.8 |
| 2-Chloro-5-hydroxybenzaldehyde | FC67157 | 25g | $1632.5 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H302+H312+H332-H315 |
| Precautionary statements | P280-P301+P312-P304+P340 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| HazardClass | IRRITANT |
| HS Code | 2913000090 |
2-CHLORO-5-HYDROXYBENZALDEHYDE price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FC67157 | 2-Chloro-5-hydroxybenzaldehyde | 7310-94-3 | 1g | $217.69 | 2026-06-04 | Buy |
| Biosynth | FC67157 | 2-Chloro-5-hydroxybenzaldehyde | 7310-94-3 | 2g | $290.24 | 2026-06-04 | Buy |
| Biosynth | FC67157 | 2-Chloro-5-hydroxybenzaldehyde | 7310-94-3 | 5g | $544.2 | 2026-06-04 | Buy |
| Biosynth | FC67157 | 2-Chloro-5-hydroxybenzaldehyde | 7310-94-3 | 10g | $997.8 | 2026-06-04 | Buy |
| Biosynth | FC67157 | 2-Chloro-5-hydroxybenzaldehyde | 7310-94-3 | 25g | $1632.5 | 2026-06-04 | Buy |
2-CHLORO-5-HYDROXYBENZALDEHYDE Chemical Properties,Uses,Production
Uses
2-Chloro-5-hydroxybenzaldehyde is used as a reagent in the synthesis of p38 inhibitors which are used for the treatment of chronic obstructive pulmonary disease. It is also used in the preparation of halogenated analogs of L-meta-tyrosine which is a biodegradable herbicide. 2-Chloro-5-hydroxybenzaldehyde may also be used as a starting material in the synthesis of chlorinated phenylephrine.
Synthesis
100-83-4
7310-94-3
56962-12-0
3-Hydroxybenzaldehyde (1 g, 10 mmol) was used as starting material and dissolved in acetonitrile (50 mL). To this solution, p-toluenesulfonic acid was added in batches at room temperature and after stirring for 5 minutes, N-chlorosuccinimide (NCS, 1.33 g, 10 mmol) was added. The reaction mixture was continued to be stirred at room temperature for 2 hours. Upon completion of the reaction, the reaction was quenched with aqueous sodium thiosulfate, followed by dilution with ethyl acetate and saturated saline. The organic layer was separated, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography with the eluent of petroleum ether/ethyl acetate (10:1 to 5:1) to afford 2-chloro-5-hydroxybenzaldehyde (Intermediate 28a, 340 mg, 21.7% yield) and 4-chloro-3-hydroxybenzaldehyde (Intermediate 28b, 310 mg, 19.7% yield) as yellow solids, respectively.The 1H NMR (CDCl3) data of 2-chloro-5-hydroxybenzaldehyde: δ10.43 (s, 1H), 7.54-7.56 (d, 1H), 7.30-7.37 (m, 2H). 1H-NMR (CDCl3) data of 4-chloro-3-hydroxybenzaldehyde: δ10.43 (s, 1H), 7.40 (d, 1H), 7.33 (d, 1H), 7.06- 7.09 (dd, 1H).
References
[1] Patent: WO2014/143799, 2014, A2. Location in patent: Page/Page column 391
[2] Patent: US2014/275528, 2014, A1. Location in patent: Paragraph 0322; 0323
2-CHLORO-5-HYDROXYBENZALDEHYDE Preparation Products And Raw materials
2-CHLORO-5-HYDROXYBENZALDEHYDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Changzhou Anxuan Chemical Co., Ltd | +86-0519-89882563 +86-18961279162 | andy@anxuanchem.com | China | 4327 | 58 |
| Aromsyn Co., Ltd. | +86-0571-85585865 +8613336024896 | CB@aromsyn.com | China | 19183 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Aceschem Inc. | +1-817863-6948 +1-（817）863-6948 | sales@aceschem.com | United States | 19632 | 58 |
View Lastest Price from 2-CHLORO-5-HYDROXYBENZALDEHYDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-05 | 2-CHLORO-5-HYDROXYBENZALDEHYDE
7310-94-3
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- 2-CHLORO-5-HYDROXYBENZALDEHYDE
7310-94-3
- $1.00
- 99%
- Career Henan Chemical Co
