ChemicalBook >> CAS DataBase List >>AMD 070
AMD 070
- CAS No.
- 558447-26-0
- Chemical Name:
- AMD 070
- Synonyms
- Mavorixafor;AMD 070;AMD-11070;AMD070/AMD-070;AMD-070 (AMD-11070);Mavorixafor(AMD-070);Mavorixafor, 10 mM in DMSO;Mavorixafor (AMD-070, X4P-001);N-(1H-benzimidazol-2-ylmethyl)-N-[(8S)-5,6,7,8-tetrahydro-8-quinolinyl]- (9CI);AMD 070 N-(1H-benziMidazol-2-ylMethyl)-N-[(8S)-5,6,7,8-tetrahydro-8-quinolinyl]- (9CI)
- CBNumber:
- CB71872364
- Molecular Formula:
- C21H27N5
- Molecular Weight:
- 349.47
- MDL Number:
- MFCD11977316
- MOL File:
- 558447-26-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-06-03 11:24:09
| Product description | Number | Pack Size | Price |
| Mavorixafor ≥95% | 28439 | 5mg | $129 |
| Mavorixafor ≥95% | 28439 | 10mg | $205 |
| Mavorixafor | 28439 | 5mg | $117 |
| Mavorixafor | 28439 | 10mg | $186 |
| (S)-N1-((1H-Benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine | IXA44726 | 5mg | $226.85 |
| More product size | |||
| Melting point | 108-110℃ |
|---|---|
| Boiling point | 597.0±50.0 °C(Predicted) |
| Density | 1.21 |
| storage temp. | Store at -20°C |
| solubility | ≥17.45 mg/mL in DMSO; ≥44.5 mg/mL in EtOH; ≥7.47 mg/mL in H2O with gentle warming |
| form | oil |
| pka | 11.65±0.10(Predicted) |
| color | brown |
| InChIKey | WVLHHLRVNDMIAR-IBGZPJMESA-N |
| SMILES | C(N(CC1NC2=CC=CC=C2N=1)[C@@H]1C2=C(CCC1)C=CC=N2)CCCN |
| FDA UNII | 0G9LGB5O2W |
| NCI Drug Dictionary | mavorixafor |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| NFPA 704 |
|
AMD 070 price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28439 | Mavorixafor ≥95% | 558447-26-0 | 5mg | $129 | 2026-04-30 | Buy |
| Cayman Chemical | 28439 | Mavorixafor ≥95% | 558447-26-0 | 10mg | $205 | 2026-04-30 | Buy |
| Cayman Chemical | 28439 | Mavorixafor | 558447-26-0 | 5mg | $117 | 2024-03-01 | Buy |
| Cayman Chemical | 28439 | Mavorixafor | 558447-26-0 | 10mg | $186 | 2024-03-01 | Buy |
| Biosynth | IXA44726 | (S)-N1-((1H-Benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine | 558447-26-0 | 5mg | $226.85 | 2026-06-04 | Buy |
AMD 070 Chemical Properties,Uses,Production
Uses
N-(1H-Benzimidazol-2-ylmethyl)-N-[(8S)-5,6,7,8-tetrahydro-8-quinolinyl]-1,4-butanediamine is a potent CXCR4 inhibitor that inhibits X4 HIV-1 replication and the gp120/CXCR4 interaction. It also has therapeutic potential for developing treatments for B-RAF wild-type and mutated melanomas.
Definition
ChEBI: AMD 070 is an aminoquinoline.
in vivo
Mavorixafor (AMD-070) (2 mg/kg, p.o.) significantly reduces the number of metastatic lung nodules in mice, and lowers the expression of human Alu DNA in mice, without body weight loss[2].
IC 50
125I-SDF-CXCR4: 13 nM (IC50); HIV-1 (NL4.3 strain): 1 nM (IC50, in MT-4 cells); HIV-1 (NL4.3 strain): 9 nM (IC50, in PBMCs); HIV-1 (NL4.3 strain): 3 nM (IC90, in MT-4 cells); HIV-1 (NL4.3 strain): 26 nM (IC90, in PBMCs)
AMD 070 Preparation Products And Raw materials
Global( 97)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39040 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +8618118463618 | sales1@artkmedchem.com | China | 39021 | 58 |
View Lastest Price from AMD 070 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-02 | Mavorixafor
558447-26-0
|
$35.00-80.00 | 98.56% | 10g | TargetMol Chemicals Inc. | ||
 |
2020-01-03 | AMD 070
558447-26-0
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- Mavorixafor
558447-26-0
- $35.00-80.00
- 98.56%
- TargetMol Chemicals Inc.
-
- AMD 070
558447-26-0
- $1.00
- 99%
- Career Henan Chemical Co
AMD 070
N-(1H-benzimidazol-2-ylmethyl)-N-[(8S)-5,6,7,8-tetrahydro-8-quinolinyl]- (9CI)
N'-(1H-Benzimidazol-2-ylmethyl)-N'-((S)-5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine
AMD 070 N-(1H-benziMidazol-2-ylMethyl)-N-[(8S)-5,6,7,8-tetrahydro-8-quinolinyl]- (9CI)
1,4-ButanediaMine, N-(1H-benziMidazol-2-ylMethyl)-N-[(8S)-5,6,7,8-tetrahydro-8-quinolinyl]-
(S)-N1-((1H-benzo[d]iMidazol-2-yl)Methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diaMine
AMD070/AMD-070
(S)-N1-((1H-Benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diami
AMD-11070
1,4-Butanediamine, N1-(1H-benzimidazol-2-ylmethyl)-N1-[(8S)-5,6,7,8-tetrahydro-8-quinolinyl]-
N'-(1h-benzimidazol-2-ylmethyl)-n'-[(8s)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine
Mavorixafor(AMD-070)
Mavorixafor,CXCR,AMD 070,Human immunodeficiency virus,AMD070,HIV,inhibit,CXC chemokine receptors,Inhibitor
Mavorixafor (AMD-070, X4P-001)
Mavorixafor, 10 mM in DMSO
AMD-070 (AMD-11070)
(S)-N1-[(2-Benzimidazolyl)methyl]-N1-(5,6,7,8-tetrahydro-8-quinolyl)-1,4-butanediamine
Mavorixafor
558447-26-0
