KEMPTIDE
- CAS No.
- 65189-71-1
- Chemical Name:
- KEMPTIDE
- Synonyms
- LRRASLG;KEMPTIDE;Nsc332190;KEMPTIDE ACETATE;5-TMR-LRRA-PS-LG;KEMPTIDE [LRRASLG];KEMPTIDE ACETATE SALT;PHOSPHATE ACCEPTOR PEPTIDE;LEU-ARG-ARG-ALA-SER-LEU-GLY;LEU-ARG-ARG-ALA-SER-LEU-GLY-OH
- CBNumber:
- CB7234741
- Molecular Formula:
- C32H61N13O9
- Molecular Weight:
- 771.91
- MDL Number:
- MFCD00076710
- MOL File:
- 65189-71-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Kemptide ≥95% | 15555 | 1mg | $49 |
| Kemptide ≥95% | 15555 | 5mg | $154 |
| Kemptide ≥95% | 15555 | 10mg | $283 |
| Kemptide ≥95% | 15555 | 25mg | $645 |
| Kemptide ≥95% | 15555 | 1mg | $44 |
KEMPTIDE price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 15555 | Kemptide ≥95% | 65189-71-1 | 1mg | $49 | 2026-04-30 | Buy |
| Cayman Chemical | 15555 | Kemptide ≥95% | 65189-71-1 | 5mg | $154 | 2026-04-30 | Buy |
| Cayman Chemical | 15555 | Kemptide ≥95% | 65189-71-1 | 10mg | $283 | 2026-04-30 | Buy |
| Cayman Chemical | 15555 | Kemptide ≥95% | 65189-71-1 | 25mg | $645 | 2026-04-30 | Buy |
| Cayman Chemical | 15555 | Kemptide ≥95% | 65189-71-1 | 1mg | $44 | 2024-03-01 | Buy |
KEMPTIDE Chemical Properties,Uses,Production
Uses
Kemptide, phosphate acceptor, is shown to be a basic serine-containing heptapeptide corresponding to a sequence from pig liver pyruvate kinase. This synthetic peptide is a substrate of PKA (cyclic AMP-dependent protein kinase) and is phosphorylated and activated after microinjection into Xenopus oocytes. Exposure of Kemptide to insulin has demonstrated an increase in activation of this agent, which can be inhibited by the catalytic subunit of phosphatase 2A.
Biological Activity
kemptide is a synthetic heptapeptide that acts as a substrate for camp-dependent protein kinase (pk) [1].cyclic amp-dependent protein kinase is the sole intracellular acceptor for cyclic amp in all cell types. protein phosphorylation by different types of protein kinase (pk) activities comprises a form of protein modification that plays an important role in the regulation of numerous biological processes [1][2].kemptide is a novel synthetic heptapeptide phosphate acceptor that acts as a substrate for camp-dependent protein kinase. kemptide had all the properties of a cytophilic substrate and could preserving cell membrane intactness when added to cultured cells. in the presence of extracellular atp and camp, different types of intact cells catalyzed the phosphorylation of kemptide with km values of 3-4 μm. kemptide phosphorylation was influenced by pki, the inhibitory protein specific for camp-pk [1]. kemptide was usually used as a substrate for detection of activities of soluble a-kinase isolated from guinea-pig lung parenchyma and from bovine tracheal smooth muscle [2][3].
References
[1]. kübler d, pyerin w, bill o, et al. evidence for ecto-protein kinase activity that phosphorylates kemptide in a cyclic amp-dependent mode. j biol chem. 1989 aug 25;264(24):14549-55.
[2]. giembycz ma, diamond j. evaluation of kemptide, a synthetic serine-containing heptapeptide, as a phosphate acceptor for the estimation of cyclic amp-dependent protein kinase activity in respiratory tissues. biochem pharmacol. 1990 jan 15;39(2):271-83.
[3]. langlands jm, rodger iw. determination of soluble camp-dependent protein kinase activity in guinea-pig tracheal smooth muscle. preferential use of kemptide as a phosphorylating substrate. biochem pharmacol. 1990 apr 15;39(8):1365-74.
KEMPTIDE Preparation Products And Raw materials
Raw materials
Preparation Products
KEMPTIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 995 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10457 | 58 |
| Hangzhou Go Top Peptide Biotech | 0571-88211921 | sales1@gotopbio.com | CHINA | 2609 | 58 |
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| Nanjing TGpeptide | +86-13347807150 | support@tgpeptide.com | China | 3279 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 |
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