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ChemicalBook >> CAS DataBase List >>Trichloroethanol

Trichloroethanol

CAS No.
115-20-8
Chemical Name:
Trichloroethanol
Synonyms
2,2,2-TRICHLOROETHANOL;CCl3CH2OH;Ethanol, 2,2,2-trichloro-;2,2,2-Trichloroethan-1-ol;2,2,2-Trichloro-1-ethanol;2,2,2-trichloroethylalcohol;Ethapon;oroethanoL;3831088306;2,2,2-TrichL
CBNumber:
CB7257753
Molecular Formula:
C2H3Cl3O
Molecular Weight:
149.4
MDL Number:
MFCD00004677
MOL File:
115-20-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:44:02
Product description Number Pack Size Price
2,2,2-Trichloroethanol ReagentPlus , ≥99% T54801 100g $47.1
2,2,2-Trichloroethanol ReagentPlus , ≥99% T54801 500g $180
2,2,2-Trichloroethanol for synthesis 8.08610 100ML $153
2,2,2-Trichloroethanol >98.0%(GC) T0622 25g $24
2,2,2-Trichloroethanol >98.0%(GC) T0622 100g $57
More product size

Trichloroethanol Properties

Melting point 17.8 °C (lit.)
Boiling point 152-154 °C (lit.)
Density 1.56 g/mL at 20 °C (lit.)
vapor density 5.16 (vs air)
vapor pressure 1 mm Hg ( 20 °C)
refractive index n20/D 1.49(lit.)
Flash point >230 °F
storage temp. Store below +30°C.
solubility 83g/l
form Liquid
pka 12.24(at 25℃)
color Clear colorless to light yellow
Specific Gravity 1.560 (20/4℃)
Odor ethereal odor
PH 5-6 (H2O, 20℃)(saturated solution)
Water Solubility Slightly soluble in water.
Sensitive Hygroscopic
Merck 14,9638
BRN 1697495
Henry's Law Constant 1.7×100 mol/(m3Pa) at 25℃, Wang et al. (2017)
InChI 1S/C2H3Cl3O/c3-2(4,5)1-6/h6H,1H2
InChIKey KPWDGTGXUYRARH-UHFFFAOYSA-N
SMILES OCC(Cl)(Cl)Cl
CAS DataBase Reference 115-20-8(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII AW835AJ62N
NIST Chemistry Reference Ethanol, 2,2,2-trichloro-(115-20-8)
EPA Substance Registry System 2,2,2-Trichloroethanol (115-20-8)
UNSPSC Code 12352104
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H318-H336
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-41-67
Safety Statements  26-39
RIDADR  1760
WGK Germany  1
RTECS  KM3850000
3-21
Autoignition Temperature 151°C
TSCA  TSCA listed
HazardClass  8
PackingGroup  III
HS Code  29055910
Storage Class 10 - Combustible liquids
Hazard Classifications Acute Tox. 4 Oral
Eye Dam. 1
STOT SE 3
Toxicity LDLo orl-rat: 500 mg/kg CRAAA7 17,258,38
NFPA 704
2
2 1

Trichloroethanol price More Price(61)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T54801 2,2,2-Trichloroethanol ReagentPlus , ≥99% 115-20-8 100g $47.1 2026-04-30 Buy
Sigma-Aldrich T54801 2,2,2-Trichloroethanol ReagentPlus , ≥99% 115-20-8 500g $180 2026-04-30 Buy
Sigma-Aldrich 8.08610 2,2,2-Trichloroethanol for synthesis 115-20-8 100ML $153 2026-04-30 Buy
TCI Chemical T0622 2,2,2-Trichloroethanol >98.0%(GC) 115-20-8 25g $24 2026-04-30 Buy
TCI Chemical T0622 2,2,2-Trichloroethanol >98.0%(GC) 115-20-8 100g $57 2026-04-30 Buy
Product number Packaging Price Buy
T54801 100g $47.1 Buy
T54801 500g $180 Buy
8.08610 100ML $153 Buy
T0622 25g $24 Buy
T0622 100g $57 Buy

Trichloroethanol Chemical Properties,Uses,Production

Chemical Properties

CLEAR COLOURLESS TO LIGHT YELLOW LIQUID

Uses

The 2,2,2-Trichloroethyl (TCE) moiety of 2,2,2-trichloroethanol is mainly used as a protecting group for acids, acetals and also phosphoryl groups of nucleotides. It can be easily cleaved by zinc reduction.
Some of its other application include:

  • Conversion of per-O-acetylated sugars to per-O-acetylated trichloroethyl derivatives.
  • Preparation of TCE ester of chlorosulfuric acid.
  • Preparation of 2,2,2-trichloroethyl acetimidate hydrochloride.

Uses

Intermediate, anesthetic.

Uses

2,2,2-Trichloroethanol (TCE) is an active metabolite of Trichloroacetaldehyde monohydrate [chloral hydrate (CH)] (T774055), a sedative/hypnotic that increases cerebral blood flow (CBF).

Definition

ChEBI: 2,2,2-trichloroethanol is a chloroethanol. It has a role as a mouse metabolite.

Safety Profile

Poison by intravenous andintraperitoneal routes. Moderately toxic by ingestion andrectal routes. Human mutation data reported. Explosivereaction with concentrated sodium hydroxide solutions.When heated to decomposition it emits toxic fumes ofClí. Us

IC 50

Human Endogenous Metabolite

515-84-4
115-20-8
Synthesis of Trichloroethanol from Ethyl trichloroacetate
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View Lastest Price from Trichloroethanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,2,2-Trichloroethanol pictures 2026-06-03 2,2,2-Trichloroethanol
115-20-8
20kg 99% 20 tons Qingdao RENAS Polymer Material Co., Ltd.
Trichloroethanol pictures 2021-07-13 Trichloroethanol
115-20-8
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
Trichloroethanol pictures 2021-07-10 Trichloroethanol
115-20-8
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
  • Trichloroethanol pictures
  • Trichloroethanol
    115-20-8
  • $10.00-15.00
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
  • Trichloroethanol pictures
  • Trichloroethanol
    115-20-8
  • $10.00-15.00
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
(Hydroxymethyl)trichloromethane 2,2,2-trichloro-ethano 2,2,2-Trichloroethyl alcohol beta,beta,.beta-Trichloroethanol beta,beta,beta-trichloroethanol Trichlorethanol BETA,BETA,BETA-TRICHLOROETHYL ALCOHOL TRICHLOROETHYL ALCOHOL trichloroethanol 2,2,2-TRICHLOROETHANOL OEKANAL, 250 MG 2,2,2-TRICHLORETHANOL 99+%(GC) Ethapon 2,2,2-Trichloroethanol,99% 1-Hydroxy-2,2,2-trichloroethane 2,2,2-Trichloroethanol, 99% 100GR 2,2,2-Trichloroethanol, 99% 500GR 2,2,2-Trichloroethanol ReagentPlus(R), >=99% Acetone ethanol 2.2.2-Trichlor 2,2,2-Trichloroethanol Vetec(TM) reagent grade, 98% 2,2,2-TRICHLOROETHANOL FOR SYNTHESIS 2-Hydroxy-1,1,1-trichloroethane 2,2,2-TrichL oroethanoL 2,2,2-Trichloroethanol > Trichloroethanol 99.0% 2,2,2-Trichloro-1-ethanol Ethanol, 2,2,2-trichloro- 2,2,2-Trichloroethanol, 10 mM in DMSO 3831088306 2,2,2-trichloroethylalcohol 2,2,2-TRICHLOROETHANOL 2,2,2-Trichloroethan-1-ol CCl3CH2OH 115-20-8 C2H3CI3O C2H3Cl3O Cl3CCH2OH ALCOHOL Oxygen Compounds Organic Building Blocks Building Blocks Alcohols C2 to C6 Miscellaneous bc0001
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