ChemicalBook >> CAS DataBase List >>Pirarubicin
Pirarubicin
- CAS No.
- 72496-41-4
- Chemical Name:
- Pirarubicin
- Synonyms
- PIRARUBICIN HYDROCHLORIDE;Therarubicin;(8S,10S)-10-[(2S,4S,5S,6S)-4-Amino-6-methyl-5-[(2S)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione;(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione;1609rb;CS-702;THP-ADM;Pirabucin;Pirarubcin;THEPRUBICIN
- CBNumber:
- CB7315796
- Molecular Formula:
- C32H37NO12
- Molecular Weight:
- 627.64
- MDL Number:
- MFCD00869742
- MOL File:
- 72496-41-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-16 07:06:08
| Product description | Number | Pack Size | Price |
| Pirarubicin ≥95% (HPLC) | P8624 | 10mg | $432 |
| Pirarubicin ≥95% (HPLC) | P8624 | 25mg | $863 |
| Pirarubicin ≥95% | 28384 | 5mg | $49 |
| Pirarubicin ≥95% | 28384 | 10mg | $93 |
| Pirarubicin ≥95% | 28384 | 25mg | $213 |
| More product size | |||
| Melting point | 188-192°C (dec.) |
|---|---|
| alpha | D25 +175 ±25° (c = 0.2 in CHCl3) |
| Boiling point | 834.7±65.0 °C(Predicted) |
| Density | 1.51±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | ethanol: soluble25mg/mL |
| form | powder |
| pka | 7.35±0.60(Predicted) |
| color | Orange to Red |
| Stability | Hygroscopic |
| InChIKey | KMSKQZKKOZQFFG-YXRRJAAWSA-N |
| SMILES | C1=C(OC)C2C(=O)C3=C(O)C4[C@@H](O[C@@H]5O[C@@H](C)[C@@H](O[C@H]6OCCCC6)[C@@H](N)C5)C[C@](O)(C(CO)=O)CC=4C(O)=C3C(=O)C=2C=C1 |
| FDA UNII | D58G680W0G |
| NCI Drug Dictionary | pirarubicin |
| ATC code | L01DB08 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H340-H350-H360FD |
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39 |
| WGK Germany | 3 |
| RTECS | QI9296000 |
| Toxicity | LD50 i.v. in mice: 27.8 mg/kg (Umezawa, 1979) |
Pirarubicin price More Price(70)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P8624 | Pirarubicin ≥95% (HPLC) | 72496-41-4 | 10mg | $432 | 2023-06-20 | Buy |
| Sigma-Aldrich | P8624 | Pirarubicin ≥95% (HPLC) | 72496-41-4 | 25mg | $863 | 2023-06-20 | Buy |
| Cayman Chemical | 28384 | Pirarubicin ≥95% | 72496-41-4 | 5mg | $49 | 2026-04-30 | Buy |
| Cayman Chemical | 28384 | Pirarubicin ≥95% | 72496-41-4 | 10mg | $93 | 2026-04-30 | Buy |
| Cayman Chemical | 28384 | Pirarubicin ≥95% | 72496-41-4 | 25mg | $213 | 2026-04-30 | Buy |
Pirarubicin Chemical Properties,Uses,Production
Description
Pirarubicin is a new anthracycline anticancer agent structurally related to doxorubicin. In acute leukemia, non-Hodgkin’s lymphoma, breast and ovariail carcinoma, pirarubicin is reportedly superior to doxorubicin and better tolerated. Its major side-effect appears to be myelosuppression, mainly in the form of leucopenia, which is potentially dose-limiting.
Chemical Properties
Red Solid
Originator
Meiji Seika (Japan)
Uses
Structural analog of Doxorubicin. Antineoplastic.
Definition
ChEBI: (7S,9S)-7-[[(2R,4S,5S,6S)-4-amino-6-methyl-5-[[(2R)-2-oxanyl]oxy]-2-oxanyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione is an anthracycline.
brand name
Pinorubicin; Therarubucin
Pirarubicin Preparation Products And Raw materials
Global( 308)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. | +86-18600796368 | sales@sjar-tech.com | China | 538 | 58 |
| Moxin Chemicals | +86-17320513646 +86-17320513646 | anna@molcoo.com | China | 10000 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 965 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 | sales@amoychem.com | China | 6366 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 | faith@widelychemical.com | CHINA | 742 | 58 |
| Beijing Yibai Biotechnology Co., Ltd | 0086-182-6772-3597 | sales04@yibaibiotech.com | CHINA | 419 | 58 |
| Jurong Coupling Biotechnology Co., Ltd. | 13656108824 | coupling278191416@hotmail.com | CHINA | 184 | 58 |
View Lastest Price from Pirarubicin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-31 | Pirarubicin
72496-41-4
|
1g | More Than 99% | 100kg/Month | BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. | ||
 |
2026-07-15 | Pirarubicin
72496-41-4
|
$32.00-108.00 | 99.15% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-03-20 | Pirarubicin
72496-41-4
|
$1.00 | 1kg | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Pirarubicin
72496-41-4
- $0.00
- More Than 99%
- BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
-
- Pirarubicin
72496-41-4
- $32.00-108.00
- 99.15%
- TargetMol Chemicals Inc.
-
- Pirarubicin
72496-41-4
- $1.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
72496-41-4(Pirarubicin)Related Search:
Pirarubicin
1,8-Dihydroxyanthraquinone
1,2,3,4-TETRAHYDRO-1,5-NAPHTHALENEDIOL
3,4-DIMETHYL-3'-METHOXYBENZOPHENONE
2-METHOXY-4'-METHYLBENZOPHENONE
1of4
THP-ADM
THEPRUBICIN
(8s-cis)-droxyacetyl)-1-methoxy
Tepirubicin
Therarubiein
THP-adriamycin
5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-alpha-L- lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-
(8S)-10α-[[3-Amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8β-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
(8S,10S)-10α-[[3-Amino-4-O-(tetrahydro-2H-pyran-2-yl)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8β-hydroxyacetyl-1-methoxy-5,12-naphthacenedione
Pirarubicin(THP-AdriaMycin)
(7S,9S)-7-((2R,4S,5S,6S)-4-amino-6-methyl-5-((R)-tetrahydro-2H-pyran-2-yloxy)-tetrahydro-2H-pyran-2-yloxy)-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
PIRARUBICIN
1609rb
4’-o-tetrahydropyranyladriamycin
4’-o-tetrahydropyranyldoxorubicin
5,12-naphthacenedione,10-((3-amino-2,3,6-trideoxy-4-o-(tetrahydro-2h-pyran-2-y
l)-alpha-l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hy
Pirarubicin(BICINS)
(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
Pinorubicin
Pirabucin
5,12-Naphthacenedione, 10-3-amino-2,3,6-trideoxy-4-O-(2R)-tetrahydro-2H-pyran-2-yl-.alpha.-L-lyxo-hexopyranosyloxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-
(8S)-10-[(2S,4S,5S,6S)-4-amino-6-methyl-5-[(2R)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione
CS-702
Pirarubcin
5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)-
Pirarubicin USP/EP/BP
(8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-6-methyl-5-(((R)-tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
Therarubicin
(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione
(8S,10S)-10-[(2S,4S,5S,6S)-4-Amino-6-methyl-5-[(2S)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione
Pirarubicin Topoisomerase II inhibitor ab142734
THP-Doxorubicin
Theprubicin|||THP
Famoxadone Impurity 14
Pirarubicin, Topoisomerase II inhibitor
Pirarubicin, 10 mM in DMSO
(8s,10s)-10-(((2r,4s,5s,6s)-4-amino-6-methyl-5-(((s)-tetrahydro-2h-pyran-2-yl)oxy)tetrahydro-2h-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
PIRARUBICIN HYDROCHLORIDE
72496-41-4
58479-32-8
C32H37NO12
Inhibitors
API
Intermediates & Fine Chemicals
Pharmaceuticals
Chiral Reagents
