1-(2-Pyridyl)piperazine
- CAS No.
- 34803-66-2
- Chemical Name:
- 1-(2-Pyridyl)piperazine
- Synonyms
- NSC13778;NSC 26624;NSC 137781;AKOS BBS-00003613;BUTTPARK 82\08-03;RARECHEM AH CK 0193;TIMTEC-BB SBB006445;2-pyridyl piperazine;2-piperazinopyridine;LABOTEST-BB LTBB000605
- CBNumber:
- CB7363328
- Molecular Formula:
- C9H13N3
- Molecular Weight:
- 163.22
- MDL Number:
- MFCD00006216
- MOL File:
- 34803-66-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1-(2-Pyridyl)piperazine 98% | 151270 | 5g | $70.9 |
| 1-(2-Pyridyl)piperazine 98% | 151270 | 25g | $137 |
| 1-(2-Pyridyl)piperazine >98.0%(GC)(T) | P1033 | 5g | $82 |
| 1-(2-Pyridyl)piperazine >98.0%(GC)(T) | P1033 | 25g | $219 |
| 1-(2-Pyridyl)piperazine | TRC-P995725-500MG | 500mg | $74 |
| More product size | |||
| Melting point | 92-94 |
|---|---|
| Boiling point | 120-122 °C/2 mmHg (lit.) |
| Density | 1.072 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Soluble in Chloroform, Methanol. |
| form | Liquid |
| pka | 8.63±0.10(Predicted) |
| color | Clear colorless to yellow |
| Water Solubility | >500 g/L (20 ºC) |
| Sensitive | Air Sensitive |
| BRN | 140423 |
| InChI | 1S/C9H13N3/c1-2-4-11-9(3-1)12-7-5-10-6-8-12/h1-4,10H,5-8H2 |
| InChIKey | GZRKXKUVVPSREJ-UHFFFAOYSA-N |
| SMILES | C1CN(CCN1)c2ccccn2 |
| CAS DataBase Reference | 34803-66-2(CAS DataBase Reference) |
| FDA UNII | 5IO1HZP7ZN |
| NIST Chemistry Reference | 1-(2-Pyridyl)piperazine(34803-66-2) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | 2735 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-34 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
1-(2-Pyridyl)piperazine price More Price(106)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 151270 | 1-(2-Pyridyl)piperazine 98% | 34803-66-2 | 5g | $70.9 | 2026-04-30 | Buy |
| Sigma-Aldrich | 151270 | 1-(2-Pyridyl)piperazine 98% | 34803-66-2 | 25g | $137 | 2026-04-30 | Buy |
| TCI Chemical | P1033 | 1-(2-Pyridyl)piperazine >98.0%(GC)(T) | 34803-66-2 | 5g | $82 | 2026-04-30 | Buy |
| TCI Chemical | P1033 | 1-(2-Pyridyl)piperazine >98.0%(GC)(T) | 34803-66-2 | 25g | $219 | 2026-04-30 | Buy |
| TRC | TRC-P995725-500MG | 1-(2-Pyridyl)piperazine | 34803-66-2 | 500mg | $74 | 2026-06-03 | Buy |
1-(2-Pyridyl)piperazine Chemical Properties,Uses,Production
Chemical Properties
clear colourless to yellow liquid
Uses
1-(2-Pyridyl)piperazine was used to determine the aliphatic and aromatic isocyanates in air.
Uses
1-(2-Pyridyl)piperazine is a compound that belongs to a class of selective α2-adrenoceptor antagonists. 1-(2-Pyridyl)piperazine shows sympatholytic activity. 1-(2-Pyridyl)piperazine is also a metaboli te of Azaperone (A802200).
General Description
1-(2-Pyridyl)piperazine is a piperazine derivative.
Synthesis
110-85-0
109-04-6
34803-66-2
Step 1: 0.1 g (0.63 mmol) of 2-bromopyridine and 0.065 g (0.75 mmol) of piperazine were placed in a dry 5 mL microwave reactor protected by nitrogen and reacted at 150 °C for 20 min. After completion of the reaction, it was cooled to room temperature. Step 2: The reaction mixture was filtered using diatomaceous earth and the filter cake was washed with ethyl acetate. Step 3: The solvent was removed by distillation under reduced pressure to obtain the crude product. Step 4: Purification of the crude product by silica gel column chromatography with eluent ratio of dichloromethane:methanol=4:1 to obtain 1-(pyridin-2-yl)piperazine in 54% yield.
References
[1] Patent: WO2008/153325, 2008, A1. Location in patent: Page/Page column 43
[2] Patent: WO2006/47415, 2006, A2. Location in patent: Page/Page column 37-38
[3] Journal of the American Chemical Society, 1949, vol. 71, p. 2731,2732
[4] Journal of Organic Chemistry, 1953, vol. 18, p. 1484,1487
[5] Patent: WO2008/62276, 2008, A2. Location in patent: Page/Page column 50
1-(2-Pyridyl)piperazine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Allfluoro pharmaceutical co. ltd. | +86-400-0216110 +86-15958047586 | sales@allfluoro.com | China | 11385 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21586 | 55 |
| Shanghai Worldyang Chemical Co.,Ltd. | +86-021-56795779 +8613651600618 | sales@worldyachem.com | China | 967 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2165 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Qiuxian Baitai New Material Co., LTD | +8618330912755 | sale2@hbyalin.com | China | 1658 | 58 |
View Lastest Price from 1-(2-Pyridyl)piperazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-11-23 | 1-(2-pyridyl) piperazine
34803-66-2
|
$25.00 | 100KG | 99% | 5ton/Month | Qiuxian Baitai New Material Co., LTD | |
 |
2020-01-10 | 1-(2-Pyridinyl)piperazine
34803-66-2
|
$1.00 | 1g | 95-99% | 1ton | Career Henan Chemical Co | |
 |
2020-01-08 | 1-(2-Pyridyl)piperazine
34803-66-2
|
1KG | 98%;99% | 1kg； 5kg；10kg；25kg | Career Henan Chemical Co |
-
- 1-(2-pyridyl) piperazine
34803-66-2
- $25.00
- 99%
- Qiuxian Baitai New Material Co., LTD
-
- 1-(2-Pyridinyl)piperazine
34803-66-2
- $1.00
- 95-99%
- Career Henan Chemical Co
-
- 1-(2-Pyridyl)piperazine
34803-66-2
- $0.01
- 98%;99%
- Career Henan Chemical Co
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