5-AMINO-1-ETHYLPYRAZOLE
- CAS No.
- 3528-58-3
- Chemical Name:
- 5-AMINO-1-ETHYLPYRAZOLE
- Synonyms
- 1-ETHYL-1H-PYRAZOL-5-AMINE;AKOS B024267;ART-CHEM-BB B024267;TIMTEC-BB SBB005554;1-ethy-pyrazol-5-aMine;5-Amino-1-ethylpyrazol;2-ethyl-3-pyrazolamine;2-ethylpyrazol-3-amine;2-Amino-1-ethylpyrazole;5-AMINO-1-ETHYLPYRAZOLE
- CBNumber:
- CB7401714
- Molecular Formula:
- C5H9N3
- Molecular Weight:
- 111.15
- MDL Number:
- MFCD00010849
- MOL File:
- 3528-58-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-Amino-1-ethylpyrazole 99% | 295760 | 1g | $83 |
| 5-Amino-1-ethylpyrazole 99% | 295760 | 5g | $253 |
| 1-Ethyl-1H-pyrazol-5-amine min. 98.0 % | A3482 | 1G | $92 |
| 1-Ethyl-1H-pyrazol-5-amine min. 98.0 % | A3482 | 5G | $277 |
| 5-Amino-1-ethylpyrazole Asreported | 258481 | 500mg | $347 |
| Melting point | 52-57 °C (lit.) |
|---|---|
| Boiling point | 92-94 °C/0.01 mmHg (lit.) |
| Density | 1.0671 (rough estimate) |
| refractive index | 1.5340 (estimate) |
| Flash point | >230 °F |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 4.18±0.10(Predicted) |
| form | solid |
| Appearance | Off-white to light yellow Solid |
| InChI | 1S/C5H9N3/c1-2-8-5(6)3-4-7-8/h3-4H,2,6H2,1H3 |
| InChIKey | FSJOLBAFVKSQQJ-UHFFFAOYSA-N |
| SMILES | CCn1nccc1N |
| CAS DataBase Reference | 3528-58-3(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 2933998090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
5-AMINO-1-ETHYLPYRAZOLE price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 295760 | 5-Amino-1-ethylpyrazole 99% | 3528-58-3 | 1g | $83 | 2023-06-20 | Buy |
| Sigma-Aldrich | 295760 | 5-Amino-1-ethylpyrazole 99% | 3528-58-3 | 5g | $253 | 2022-05-15 | Buy |
| TCI Chemical | A3482 | 1-Ethyl-1H-pyrazol-5-amine min. 98.0 % | 3528-58-3 | 1G | $92 | 2026-04-30 | Buy |
| TCI Chemical | A3482 | 1-Ethyl-1H-pyrazol-5-amine min. 98.0 % | 3528-58-3 | 5G | $277 | 2026-04-30 | Buy |
| Usbiological | 258481 | 5-Amino-1-ethylpyrazole Asreported | 3528-58-3 | 500mg | $347 | 2026-06-03 | Buy |
5-AMINO-1-ETHYLPYRAZOLE Chemical Properties,Uses,Production
Uses
5-Amino-1-ethylpyrazole is a heterocyclic building block, has been used in the preparation of 1-protected-1H-pyrazolo[3,4-b]pyridines.
Synthesis
75-07-0
107-13-1
3528-58-3
1. Hydrazine hydrate (98.7 g, 1.97 mol) was slowly added dropwise to a solution of 2-acrylonitrile (100 g, 1.88 mol) in tetrahydrofuran (350 ml) at 0-5 °C. 2. The reaction mixture was stirred at room temperature for 3 h. 3. Acetaldehyde (86.9 g, 1.9 mol) was slowly added dropwise to the above mixture, and stirring was continued for 3 h at room temperature. 4. The solvent was removed by distillation under reduced pressure to give a yellow oil. 5. The oil was dissolved in n-butanol (100 ml), followed by addition of a solution of n-butanol (250 ml) containing potassium tert-butanolate (221 g, 1.9 mol). 6. The reaction mixture was gradually heated from room temperature to 120 °C and maintained at this temperature for 3 h. 7. After completion of the reaction, the reaction was cooled to room temperature, and diluted with water (500 ml). 8. ) for dilution. 8. The reaction mixture was extracted with ethyl acetate (3 x 500 ml). 9. The organic layers were combined and dried over anhydrous sodium sulfate, followed by concentration in vacuo. 10. Purification was carried out by column chromatography using silica gel saturated with triethylamine (100-200 mesh), with 20% ethyl acetate in hexane as eluent. 11. The target fractions were collected to afford 1-ethyl-1H-pyrazol-5-amine, Yield: 66.0 g (1.0 g). 12. , Yield: 66.0 g (15% yield), mass spectrum (m/z): (M+H)+ 111.98.
References
[1] Patent: WO2010/46791, 2010, A1. Location in patent: Page/Page column 30-31
5-AMINO-1-ETHYLPYRAZOLE Preparation Products And Raw materials
5-AMINO-1-ETHYLPYRAZOLE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3997 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5973 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| RR Scientific LLC | +86-13917743231 | sales@rrscientific.com | United States | 878 | 58 |
View Lastest Price from 5-AMINO-1-ETHYLPYRAZOLE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-07-20 | 5-Amino-1-ethylpyrazol
3528-58-3
|
$1.00 | 1Kg | 98% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-12-26 | 5-AMINO-1-ETHYLPYRAZOLE
3528-58-3
|
$9.80 | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- 5-Amino-1-ethylpyrazol
3528-58-3
- $1.00
- 98%
- Shaanxi Dideu Medichem Co. Ltd
-
- 5-AMINO-1-ETHYLPYRAZOLE
3528-58-3
- $9.80
- ≥99%
- Career Henan Chemical Co
3528-58-3(5-AMINO-1-ETHYLPYRAZOLE)Related Search:
1of4
