2-Amino-4,5-dimethoxybenzoic acid
- CAS No.
- 5653-40-7
- Chemical Name:
- 2-Amino-4,5-dimethoxybenzoic acid
- Synonyms
- 4,5-Dimethoxy-2-aminobenzoic acid;LR-79;TIMTEC-BB SBB007800;RARECHEM AL BO 1315;6-AMINOVERATRIC ACID;LABOTEST-BB LT00080709;4,5-DimethoxyanthraniL;5-diMethoxybenzoic acid;4,5-Dimethoxyanthranilic;2-Amino-4,5-dimethoxybenzoic
- CBNumber:
- CB7420531
- Molecular Formula:
- C9H11NO4
- Molecular Weight:
- 197.19
- MDL Number:
- MFCD00011671
- MOL File:
- 5653-40-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Amino-4,5-dimethoxybenzoic acid 98% | 252042 | 5g | $53.9 |
| 4,5-Dimethoxyanthranilic Acid >98.0%(HPLC)(T) | D2013 | 10g | $45 |
| 2-Amino-4,5-dimethoxybenzoic Acid | TRC-A604940-5G | 5g | $62 |
| 2-Amino-4,5-dimethoxybenzoic Acid | TRC-A604940-25G | 25g | $84 |
| 2-Amino-4,5-dimethoxybenzoic Acid | TRC-A604940-10G | 10g | $65 |
| More product size | |||
| Melting point | 169-173 °C (dec.) (lit.) |
|---|---|
| Boiling point | 334.28°C (rough estimate) |
| Density | 1.3075 (rough estimate) |
| refractive index | 1.5270 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Acetontrile (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 2.35±0.10(Predicted) |
| color | White, beige, or gray to brown |
| Water Solubility | Soluble in Methanol and Water |
| BRN | 782814 |
| Stability | May be Sensitive To Air Oxidation, Light Sensitive |
| Major Application | peptide synthesis |
| InChI | InChI=1S/C9H11NO4/c1-13-7-3-5(9(11)12)6(10)4-8(7)14-2/h3-4H,10H2,1-2H3,(H,11,12) |
| InChIKey | HJVAVGOPTDJYOJ-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC(OC)=C(OC)C=C1N |
| CAS DataBase Reference | 5653-40-7(CAS DataBase Reference) |
| UNSPSC Code | 12352106 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 37/39-26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29225090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2-Amino-4,5-dimethoxybenzoic acid price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 252042 | 2-Amino-4,5-dimethoxybenzoic acid 98% | 5653-40-7 | 5g | $53.9 | 2026-04-30 | Buy |
| TCI Chemical | D2013 | 4,5-Dimethoxyanthranilic Acid >98.0%(HPLC)(T) | 5653-40-7 | 10g | $45 | 2026-04-30 | Buy |
| TRC | TRC-A604940-5G | 2-Amino-4,5-dimethoxybenzoic Acid | 5653-40-7 | 5g | $62 | 2026-06-03 | Buy |
| TRC | TRC-A604940-25G | 2-Amino-4,5-dimethoxybenzoic Acid | 5653-40-7 | 25g | $84 | 2026-06-03 | Buy |
| TRC | TRC-A604940-10G | 2-Amino-4,5-dimethoxybenzoic Acid | 5653-40-7 | 10g | $65 | 2026-06-03 | Buy |
2-Amino-4,5-dimethoxybenzoic acid Chemical Properties,Uses,Production
Chemical Properties
Brown Solid
Uses
2-Amino-4,5-dimethoxybenzoic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
4998-07-6
5653-40-7
General procedure for the synthesis of 2-amino-4,5-dimethoxybenzoic acid from 6-nitroveratric acid: first, 48.13 g (0.729 mol) of KOH pellets (85% purity) were dissolved in 250 ml of ice water. Subsequently, 50 g (0.207 mol) of methyl-4,5-dimethoxy-2-nitrobenzoate (1) was added to this clarified solution, and the resulting green suspension was heated to 70 °C. During heating, the color of the solution shifted to dark red. The progress of the reaction was monitored by HPLC and upon completion of the reaction, the solution was cooled to room temperature and the pH was adjusted to 6.6 with 34.6 g (0.570 mol) of glacial acetic acid.The obtained red suspension was hydrogenated at 50 °C and 3.5 bar pressure using 1 g of 10% Pd/C catalyst until the reaction was terminated. Upon completion of hydrogenation, the solution was filtered and the pH was adjusted to 5.1 with 31.82 g (0.525 mol) of glacial acetic acid under the protection of an inert gas.The light green suspension formed was stirred at room temperature for 30 min, followed by cooling to 5 °C and continued stirring for 30 min. The product (2) was obtained by filtration, washed in two batches with a total of 250 ml of ice water and finally dried in a vacuum oven at 55°C for 12 hrs. This process yielded 35.18 g (0.173 mol, 83% yield) of light gray crystalline product.
References
[1] Organic and Biomolecular Chemistry, 2018, vol. 16, # 28, p. 5119 - 5135
[2] Chemistry - An Asian Journal, 2017, vol. 12, # 7, p. 785 - 791
[3] Patent: US2008/319194, 2008, A1. Location in patent: Page/Page column 4
[4] Molecules, 2018, vol. 23, # 1,
[5] RSC Advances, 2016, vol. 6, # 81, p. 77717 - 77734
2-Amino-4,5-dimethoxybenzoic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Dexinjia Bio&Tech Co., Ltd | +86-0531-82375818 +86-15064153060 | sales@jndxj.com | China | 1285 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5228 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Hangzhou Cyanochem Co., Ltd. | +86 17788583750 | sales@cyanochem.com | CHINA | 281 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3991 | 58 |
View Lastest Price from 2-Amino-4,5-dimethoxybenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-05 | 2-Amino-4,5-dimethoxybenzoic acid
5653-40-7
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-05-28 | 2-Amino-4,5-dimethoxybenzoic acid
5653-40-7
|
$60.00 | 1KG | 99.9% | 100000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2025-05-23 | 2-Amino-4,5-dimethoxybenzoic acid
5653-40-7
|
$10.00 | 1kg | 99% | 20 ton | Hebei Zhuanglai Chemical Trading Co Ltd |
-
- 2-Amino-4,5-dimethoxybenzoic acid
5653-40-7
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 2-Amino-4,5-dimethoxybenzoic acid
5653-40-7
- $60.00
- 99.9%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 2-Amino-4,5-dimethoxybenzoic acid
5653-40-7
- $10.00
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
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