ANHYDROTETRACYCLINE HYDROCHLORIDE
- CAS No.
- 13803-65-1
- Chemical Name:
- ANHYDROTETRACYCLINE HYDROCHLORIDE
- Synonyms
- AnhydrotetracyclineHCl;Tetracycline Anhydro HCl;Aureomycin EP impurity J;Anhydrotetracycline HCl, EvoPure;ANHYDROTETRACYCLINE HYDROCHLORIDE;Anhydrotetracycline hydrochloride RS;5A,6-ANHYDROTETRACYCLINEHYDROCHLORIDE;Anhydrotetracycline hydrochloride CRS;Anhydrotetracycline hydrochloride ,97%;C10258000 AnhydrotetracyclinEHydrochloride
- CBNumber:
- CB7438626
- Molecular Formula:
- C22H23ClN2O7
- Molecular Weight:
- 462.88
- MDL Number:
- MFCD00151453
- MOL File:
- 13803-65-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Anhydrotetracycline Hydrochloride pharmaceutical secondary standard, certified reference material | PHR3175 | 50MG | $593 |
| Anhydrotetracycline hydrochloride European Pharmacopoeia (EP) Reference Standard | A1200000 | 25 mg | $254 |
| Anhydrotetracycline hydrochloride certified reference material, TraceCERT | 94664 | 10mg | $317 |
| Anhydrotetracycline hydrochloride VETRANAL?, analytical standard | 37919 | 100mg | $274 |
| Anhydrotetracycline hydrochloride United States Pharmacopeia (USP) Reference Standard | 1035708 | 25mg | $1270 |
| More product size | |||
| Melting point | 223 °C |
|---|---|
| RTECS | QI7860000 |
| storage temp. | Refrigerator |
| solubility | Soluble in ethanol, DMSO, or DMF |
| form | Powder |
| color | Yellow to bright yellow |
| Sensitive | Moisture Sensitive |
| BRN | 4228856 |
| Stability | Hygroscopic |
| Major Application | clinical testing |
| InChIKey | XBSQEFHDCDFNJU-WPJNXPDPSA-N |
| SMILES | Cl[H].[H][C@@]12Cc3c(C)c4cccc(O)c4c(O)c3C(=O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C |
| FDA UNII | OVG14H105R |
| EPA Substance Registry System | 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, hydrochloride (1:1), (4S,4aS,12aS)- (13803-65-1) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H361 |
| Precautionary statements | P201-P202-P264b-P280i-P305+P351+P338-P308+P313-P403-P501c |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Hazard Codes | Xn |
| Risk Statements | 63-36 |
| Safety Statements | 36/37/39-26 |
| WGK Germany | 3 |
| HS Code | 29413020 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 4 Oral Repr. 1B |
ANHYDROTETRACYCLINE HYDROCHLORIDE price More Price(67)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR3175 | Anhydrotetracycline Hydrochloride pharmaceutical secondary standard, certified reference material | 13803-65-1 | 50MG | $593 | 2026-04-30 | Buy |
| Sigma-Aldrich | A1200000 | Anhydrotetracycline hydrochloride European Pharmacopoeia (EP) Reference Standard | 13803-65-1 | 25 mg | $254 | 2026-04-30 | Buy |
| Sigma-Aldrich | 94664 | Anhydrotetracycline hydrochloride certified reference material, TraceCERT | 13803-65-1 | 10mg | $317 | 2026-04-30 | Buy |
| Sigma-Aldrich | 37919 | Anhydrotetracycline hydrochloride VETRANAL?, analytical standard | 13803-65-1 | 100mg | $274 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1035708 | Anhydrotetracycline hydrochloride United States Pharmacopeia (USP) Reference Standard | 13803-65-1 | 25mg | $1270 | 2026-04-30 | Buy |
ANHYDROTETRACYCLINE HYDROCHLORIDE Chemical Properties,Uses,Production
Description
The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression. Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-
Chemical Properties
yellow to bright yellow powder
Uses
Anhydrotetracycline is a degradation product of tetracycline, formed by dehydration at the C6 position under acidic conditions to aromatise the B ring. Anhydrotetracycline is an important standard for monitoring tetracycline stability. Although the degradation is associated with a loss of antibiotic activity, anhydrotetracycline is considered biologically active and is thought responsible for aspects of tetracycline toxicity.
Uses
A Tetracycline derivative exhibiting no antibiotic activity, a useful effector of tetracycline-dependent gene expression in bacterial expression systems.
Uses
Anhydrotetracycline hydrochloride is a salt of a degradation product of tetracycline, formed by dehydration at the C6 position under acidic conditions to aromatise the B ring. Anhydrotetracycline is an important standard for monitoring tetracycline stability. Although the degradation is associated with a loss of antibiotic activity, anhydrotetracycline is considered biologically active and is thought responsible for aspects of tetracycline toxicity.
IC 50
Tetracycline
References
[1] M GOSSEN H B. Anhydrotetracycline, a novel effector for tetracycline controlled gene expression systems in eukaryotic cells.[J]. Nucleic Acids Research, 1993, 21 18: 4411-4412. DOI: 10.1093/nar/21.18.4411
[2] B RASMUSSEN. Molecular basis of tetracycline action: identification of analogs whose primary target is not the bacterial ribosome.[J]. Antimicrobial Agents and Chemotherapy, 1991, 35 11: 2306-2311. DOI: 10.1128/aac.35.11.2306
ANHYDROTETRACYCLINE HYDROCHLORIDE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 27945 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| VladaChem GmbH | +49-7246-3082843 | info@vladachem.de | Germany | 1859 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49962 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
View Lastest Price from ANHYDROTETRACYCLINE HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Anhydrotetracycline hydrochloride
13803-65-1
|
$32.00-107.00 | 98.00% | 10g | TargetMol Chemicals Inc. |
-
- Anhydrotetracycline hydrochloride
13803-65-1
- $32.00-107.00
- 98.00%
- TargetMol Chemicals Inc.
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