3-BROMO-4-CHLORO-5-NITROPYRIDINE
- CAS No.
- 31872-63-6
- Chemical Name:
- 3-BROMO-4-CHLORO-5-NITROPYRIDINE
- Synonyms
- 4-Chloro-5-Bromo-3-Nitropyridine;3-BROMO-4-CHLORO-5-NITROPYRIDINE;3-Nitro-4-chloro-5-bromopyridine;Pyridine, 3-broMo-4-chloro-5-nitro-;3-BroMo-4-chloro-5-nitropyridine HCl;3-BROMO-4-CHLORO-5-NITROPYRIDINE ISO 9001：2015 REACH
- CBNumber:
- CB7664256
- Molecular Formula:
- C5H2BrClN2O2
- Molecular Weight:
- 237.44
- MDL Number:
- MFCD07368836
- MOL File:
- 31872-63-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Bromo-4-chloro-5-nitropyridine Asreported | 262012 | 1g | $382 |
| 3-Bromo-4-chloro-5-nitropyridine Asreported | 262012 | 2g | $542 |
| 3-Bromo-4-chloro-5-nitropyridine Asreported | 262012 | 5g | $686 |
| 3-Bromo-4-chloro-5-nitropyridine Asreported | 262012 | 10g | $907 |
| 3-Bromo-4-chloro-5-nitropyridine Asreported | 262012 | 25g | $1274 |
| More product size | |||
| Melting point | 49-50℃ |
|---|---|
| Boiling point | 285℃ |
| Density | 1.936 |
| Flash point | 126℃ |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| form | solid |
| pka | -0.88±0.10(Predicted) |
| color | Light yellow |
| InChI | InChI=1S/C5H2BrClN2O2/c6-3-1-8-2-4(5(3)7)9(10)11/h1-2H |
| InChIKey | FTQGEZJTBYMEIH-UHFFFAOYSA-N |
| SMILES | C1=NC=C([N+]([O-])=O)C(Cl)=C1Br |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| RIDADR | UN2811 |
| HazardClass | IRRITANT |
| HS Code | 2933399990 |
3-BROMO-4-CHLORO-5-NITROPYRIDINE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 262012 | 3-Bromo-4-chloro-5-nitropyridine Asreported | 31872-63-6 | 1g | $382 | 2026-06-03 | Buy |
| Usbiological | 262012 | 3-Bromo-4-chloro-5-nitropyridine Asreported | 31872-63-6 | 2g | $542 | 2026-06-03 | Buy |
| Usbiological | 262012 | 3-Bromo-4-chloro-5-nitropyridine Asreported | 31872-63-6 | 5g | $686 | 2026-06-03 | Buy |
| Usbiological | 262012 | 3-Bromo-4-chloro-5-nitropyridine Asreported | 31872-63-6 | 10g | $907 | 2026-06-03 | Buy |
| Usbiological | 262012 | 3-Bromo-4-chloro-5-nitropyridine Asreported | 31872-63-6 | 25g | $1274 | 2026-06-03 | Buy |
3-BROMO-4-CHLORO-5-NITROPYRIDINE Chemical Properties,Uses,Production
Application
3-Bromo-4-chloro-5-nitropyridine can be used as an organic synthesis intermediate and a pharmaceutical intermediate in laboratory research and development processes and in the synthesis of pharmaceutical chemicals.
Synthesis
31872-65-8
31872-63-6
Step 2. Synthesis of 3-bromo-4-chloro-5-nitropyridine The product of Step 1, 3-bromo-4-hydroxy-5-nitropyridine (6.57 g, 30 mmol), was slowly added to phosphoryl chloride (50 mL) under ice bath cooling conditions. Subsequently, N,N-diethylaniline (4.77 mL, 30 mmol) was added dropwise to the stirring reaction mixture. The reaction mixture was gradually warmed to room temperature and then heated to reflux for 2 hours. After completion of the reaction, the mixture was concentrated under reduced pressure and the residue was carefully poured into ice water. The aqueous phase was extracted with ether and the organic phases were combined and washed sequentially twice with water and once with brine. Finally, the organic phase was concentrated to give a brown oil, which solidified to the target product 3-bromo-4-chloro-5-nitropyridine in a yield of 8.01 g (yield >100%) after standing.
References
[1] Patent: WO2005/37198, 2005, A2. Location in patent: Page/Page column 26-27
[2] Tetrahedron Letters, 2012, vol. 53, # 4, p. 377 - 379
[3] Journal of Medicinal Chemistry, 2014, vol. 57, # 6, p. 2462 - 2471
[4] Justus Liebigs Annalen der Chemie, 1937, vol. 529, p. 291
3-BROMO-4-CHLORO-5-NITROPYRIDINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
View Lastest Price from 3-BROMO-4-CHLORO-5-NITROPYRIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-05 | 3-BROMO-4-CHLORO-5-NITROPYRIDINE
31872-63-6
|
$130.00-873.00 | 50g | 99% | 30 | Zibo Hangyu Biotechnology Development Co., Ltd | |
 |
2025-11-18 | 3-BROMO-4-CHLORO-5-NITROPYRIDINE
31872-63-6
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2025-04-04 | 3-Bromo-4-chloro-5-nitropyridine
31872-63-6
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 3-BROMO-4-CHLORO-5-NITROPYRIDINE
31872-63-6
- $130.00-873.00
- 99%
- Zibo Hangyu Biotechnology Development Co., Ltd
-
- 3-BROMO-4-CHLORO-5-NITROPYRIDINE
31872-63-6
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 3-Bromo-4-chloro-5-nitropyridine
31872-63-6
- 98%
- Henan Aochuang Chemical Co.,Ltd.
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