7-Bromo-5-chloro-1H-indazole
- CAS No.
- 875305-86-5
- Chemical Name:
- 7-Bromo-5-chloro-1H-indazole
- Synonyms
- 1H-Indazole, 7-bromo-5-chloro-;7-Bromo-5-chloro-1H-indazole;7-Bromo-5-chloro-1H-indazole97%;7-Bromo-5-chloro-1H-indazole 97%;7-bromo-5-chloro-1H-indazole - [B25997]
- CBNumber:
- CB7956951
- Molecular Formula:
- C7H4BrClN2
- Molecular Weight:
- 231.48
- MDL Number:
- MFCD09258643
- MOL File:
- 875305-86-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 7-Bromo-5-chloro-1H-indazole 97% | OR8313 | 1g | $100 |
| 7-Bromo-5-chloro-1H-indazole 97% | OR8313 | 5g | $305 |
| 7-Bromo-5-chloro-1H-indazole 97% | OR8313 | 10g | $520 |
| 7-Bromo-5-chloro-1H-indazole 97% | OR8313 | 25g | $1038 |
| 7-Bromo-5-chloro-1H-indazole 97% | OR8313 | 100g | $2863 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Hazard Note | Irritant |
| HS Code | 2933998090 |
7-Bromo-5-chloro-1H-indazole price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR8313 | 7-Bromo-5-chloro-1H-indazole 97% | 875305-86-5 | 1g | $100 | 2026-06-04 | Buy |
| Apolloscientific | OR8313 | 7-Bromo-5-chloro-1H-indazole 97% | 875305-86-5 | 5g | $305 | 2026-06-04 | Buy |
| Apolloscientific | OR8313 | 7-Bromo-5-chloro-1H-indazole 97% | 875305-86-5 | 10g | $520 | 2026-06-04 | Buy |
| Apolloscientific | OR8313 | 7-Bromo-5-chloro-1H-indazole 97% | 875305-86-5 | 25g | $1038 | 2026-06-04 | Buy |
| Apolloscientific | OR8313 | 7-Bromo-5-chloro-1H-indazole 97% | 875305-86-5 | 100g | $2863 | 2026-06-04 | Buy |
7-Bromo-5-chloro-1H-indazole Chemical Properties,Uses,Production
Synthesis
95-69-2
875305-86-5
The general procedure for the synthesis of 7-bromo-5-chloro-1H-indazole from 4-chloro-2-methylaniline was as follows: 2-bromo-4-chloro-6-methylaniline (13.2 g, 59.90 mmol) was suspended in 24% hydrochloric acid (40 mL). The stirred mixture was cooled to 0°C and a solution of sodium nitrite (4.54 g, 65.90 mmol) in water (10 mL) was added slowly and dropwise over 30 minutes. Subsequently, the mixture was warmed to about 50°C and the pH was adjusted with sodium acetate to 5. The mixture was maintained at 0°C and a solution of 2-methyl-2-propanethiol (6.8 mL, 59.9 mmol) in ethanol (40 mL) was added in batches over 30 minutes. After addition, stirring was continued at 0°C for 30 min, then the reaction mixture was poured into crushed ice and extracted with ethyl acetate (2×). The organic phases were combined, washed with brine (2×), dried over anhydrous sodium sulfate, filtered and concentrated. The resulting residue was dissolved in dimethyl sulfoxide (50 mL) and transferred to a solution of potassium tert-butoxide (53.7 g, 479 mmol) in dimethyl sulfoxide (200 mL) via cannula at 0°C. The residue was extracted with ethyl acetate (2×). The ice bath was removed and stirring was continued for 30 min. Subsequently, the reaction mixture was poured into a mixture of crushed ice (400 mL) and 10% hydrochloric acid (200 mL), a precipitate was precipitated and collected by filtration. The resulting solid was ground with hexane to give 7.5 g (54% yield) of brown powdery product.1H-NMR (CDCl3, 300 MHz) δ 7.97 (s, 1H), 7.60 (s, 1H), 7.44 (s, 1H). MS: 232.90 (MH)+.
References
[1] Patent: US2009/18132, 2009, A1. Location in patent: Page/Page column 56
7-Bromo-5-chloro-1H-indazole Preparation Products And Raw materials
Raw materials
Preparation Products
7-Bromo-5-chloro-1H-indazole Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9984 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35896 | 56 |
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