4-amino-2,6-di-tert-butylphenol
- CAS No.
- 950-58-3
- Chemical Name:
- 4-amino-2,6-di-tert-butylphenol
- Synonyms
- 4-amino-2,6-di-tert-butylphenol;2,6-di-tert-butyl-4-aminophenol;Phenol, 4-aMino-2,6-bis(1,1-diMethylethyl)-
- CBNumber:
- CB81014446
- Molecular Formula:
- C14H23NO
- Molecular Weight:
- 221.34
- MDL Number:
- MFCD01002935
- MOL File:
- Mol file
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Amino-2,6-di-tert-butylphenol 95+% | A57968 | 100mg | $520 |
| 4-Amino-2,6-di-tert-butylphenol 95+% | A57968 | 1g | $2200 |
| 4-Amino-2,6-di-tert-butylphenol 95% | AA0066PJ | 250mg | $379 |
| 4-Amino-2,6-di-tert-butylphenol 95% | AA0066PJ | 1g | $908 |
| 4-Amino-2,6-di-tert-butylphenol 95+% | CD12003026 | 1g | $365 |
4-amino-2,6-di-tert-butylphenol price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | A57968 | 4-Amino-2,6-di-tert-butylphenol 95+% | 950-58-3 | 100mg | $520 | 2026-05-06 | Buy |
| Synthonix | A57968 | 4-Amino-2,6-di-tert-butylphenol 95+% | 950-58-3 | 1g | $2200 | 2026-05-06 | Buy |
| aablocks | AA0066PJ | 4-Amino-2,6-di-tert-butylphenol 95% | 950-58-3 | 250mg | $379 | 2026-05-28 | Buy |
| aablocks | AA0066PJ | 4-Amino-2,6-di-tert-butylphenol 95% | 950-58-3 | 1g | $908 | 2026-05-28 | Buy |
| Crysdot | CD12003026 | 4-Amino-2,6-di-tert-butylphenol 95+% | 950-58-3 | 1g | $365 | 2026-05-27 | Buy |
4-amino-2,6-di-tert-butylphenol Chemical Properties,Uses,Production
Application
4-Amino-2,6-di-tert-butylphenol, also known as 2,6-di-tert-butyl-4-aminophenol, is an important hindered phenolic antioxidant intermediate, widely used in rubber, plastics, pharmaceuticals, synthetic fibers, food, petroleum products, and cosmetics for heat oxidation resistance.
Synthesis
728-40-5
950-58-3
The general procedure for the synthesis of 4-amino-2,6-di-tert-butylphenol from 2,6-di-tert-butyl-4-nitrophenol is as follows: 3.6 g (14 mmol) of 4-nitro-2,6-bis(1,1-dimethylethyl)phenol (Literature Ref. J. Org. Chem. 1968, 33(1), 223-226) was dissolved in 60 mL of a mixed solvent of ethanol and methylene chloride (volume ratio 2:1) in a 250 mL Parr reaction vessel. (2:1 v/v) in a 250 mL Parr reaction flask. A catalytic amount of 10% Pd/C catalyst was added. The reaction mixture was stirred at 20°C and 20 psi hydrogen pressure for 2 hours. Upon completion of the reaction, the catalyst was removed by diatomaceous earth filtration and the filtrate was concentrated to dryness under reduced pressure. The resulting reddish brown powder was suspended in 30 mL of heptane, filtered and washed with the same volume of heptane. The resulting product was a salmon-colored powder in 50% yield (1.56 g). Melting point: 123-124 °C. NMR hydrogen spectrum (100 MHz, CDCl3, δ): 6.60 (s, 2H, aromatic hydrogen); 4.65 (wide s, 1H, hydroxyl hydrogen); 3.15 (wide s, 2H, amino hydrogen); 1.42 (s, 18H, tert-butyl hydrogen).
References
[1] Patent: US6335445, 2002, B1. Location in patent: Page column 72
[2] Patent: US6653312, 2003, B1. Location in patent: Page/Page column 45
[3] Patent: US6340700, 2002, B1. Location in patent: Page column 33
[4] Patent: US2003/78420, 2003, A1
[5] Patent: US6809088, 2004, B2
4-amino-2,6-di-tert-butylphenol Preparation Products And Raw materials
Raw materials
Preparation Products
4-amino-2,6-di-tert-butylphenol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33324 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| ShangHai IKSChem Technology Co.,LTD | zheng@ikschem.com | China | 2059 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10266 | 58 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4710 | 55 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9793 | 50 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16676 | 50 |
