3-Chloro-4-nitrobenzonitrile
- CAS No.
- 34662-29-8
- Chemical Name:
- 3-Chloro-4-nitrobenzonitrile
- Synonyms
- 3-Chloro-4-nitrobenzonitrile;Benzonitrile, 3-chloro-4-nitro-
- CBNumber:
- CB82144676
- Molecular Formula:
- C7H3ClN2O2
- Molecular Weight:
- 182.56
- MDL Number:
- MFCD02317167
- MOL File:
- 34662-29-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Chloro-4-nitrobenzonitrile | JBA66229 | 5g | $354 |
| 3-Chloro-4-nitrobenzonitrile 98% | OR938611 | 250mg | $75 |
| 3-Chloro-4-nitrobenzonitrile 98% | OR938611 | 1g | $115 |
| 3-Chloro-4-nitrobenzonitrile 98% | OR938611 | 250mg | $75 |
| 3-Chloro-4-nitrobenzonitrile 98% | OR938611 | 1g | $115 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2926907090 |
3-Chloro-4-nitrobenzonitrile price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | JBA66229 | 3-Chloro-4-nitrobenzonitrile | 34662-29-8 | 5g | $354 | 2026-06-04 | Buy |
| Apolloscientific | OR938611 | 3-Chloro-4-nitrobenzonitrile 98% | 34662-29-8 | 250mg | $75 | 2026-06-04 | Buy |
| Apolloscientific | OR938611 | 3-Chloro-4-nitrobenzonitrile 98% | 34662-29-8 | 1g | $115 | 2026-06-04 | Buy |
| Apolloscientific | OR938611 | 3-Chloro-4-nitrobenzonitrile 98% | 34662-29-8 | 250mg | $75 | 2026-06-04 | Buy |
| Apolloscientific | OR938611 | 3-Chloro-4-nitrobenzonitrile 98% | 34662-29-8 | 1g | $115 | 2026-06-04 | Buy |
3-Chloro-4-nitrobenzonitrile Chemical Properties,Uses,Production
Synthesis
21803-75-8
34662-29-8
The general procedure for the synthesis of 3-chloro-4-nitrobenzonitrile from 4-amino-3-chlorobenzonitrile is as follows: sodium borate tetrahydrate (32.5 g, 211.2 mmol) was suspended in 195 ml of acetic acid and heated until the temperature of the reaction mixture exceeded 50 °C. At this temperature, 2-chloro-4-cyanobenzenamine (5.93 g, 38.9 mmol) was added in batches over a period of 1 hour. After the addition was completed, the reaction mixture was placed in an oil bath at 62°C and continued to be heated with stirring for 2 hours. After completion of the reaction, it was cooled to room temperature and the reaction mixture was poured into 1 L of ice water. The aqueous layer was extracted with ether (3×), the organic layers were combined and washed with deionized water (2×) and dried with anhydrous magnesium sulfate. The desiccant was removed by filtration and the solvent was removed by evaporation under reduced pressure. The residue was separated by silica gel column chromatography using ether/petroleum ether (1:3) as eluent to give 5.27 g (74% yield) of the target product 3-chloro-4-nitrobenzonitrile.
References
[1] Patent: US2006/122189, 2006, A1. Location in patent: Page/Page column 22
[2] Chemical and Pharmaceutical Bulletin, 1992, vol. 40, # 9, p. 2399 - 2409
[3] Patent: US2003/69257, 2003, A1
[4] Patent: EP1247810, 2002, A1. Location in patent: Page 59
3-Chloro-4-nitrobenzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
3-Chloro-4-nitrobenzonitrile Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Anxuan Chemical Co., Ltd | +86-0519-89882563 +86-18961279162 | andy@anxuanchem.com | China | 4327 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 6085 | 58 |
| Hangzhou Collab Medicine Co.,Ltd. | +8615936229464 | candice@collab-med.com | China | 999 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Acesys Pharmatech | 18860950986 | tangmanman@zenjipharma.com | China | 1733 | 55 |
| Nanjing ShengSai Chemical Co., Ltd. | 025-85205967 13951876367 | shengsaichem@163.com | China | 818 | 58 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14916 | 59 |
