2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine
![2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine Structure](CAS2/GIF/1060816-67-2.gif)
- CAS No.
- 1060816-67-2
- Chemical Name:
- 2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine
- Synonyms
- 2-Chloro-7-Methyl-7H-pyrr...;2-Chloro-7-methyl-pyrrolo[2,3-d]pyrimidine;2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine;7H-Pyrrolo[2,3-d]pyrimidine, 2-chloro-7-methyl-
- CBNumber:
- CB82485470
- Molecular Formula:
- C7H6ClN3
- Molecular Weight:
- 167.6
- MDL Number:
- MFCD13189420
- MOL File:
- 1060816-67-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine | 112312 | 1.00g | $75 |
| 2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine | 112312 | 5.00g | $213 |
| 2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine | 112312 | 25.00g | $826 |
| 2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine 97.0% | C7614 | 100mg | $70 |
| 2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine 97.0% | C7614 | 250mg | $77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P362+P364 |
| RIDADR | UN2811 |
| HS Code | 2933998090 |
2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 112312 | 2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine | 1060816-67-2 | 1.00g | $75 | 2026-05-18 | Buy |
| Matrix Scientific | 112312 | 2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine | 1060816-67-2 | 5.00g | $213 | 2026-05-18 | Buy |
| Matrix Scientific | 112312 | 2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine | 1060816-67-2 | 25.00g | $826 | 2026-05-18 | Buy |
| Synthonix | C7614 | 2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine 97.0% | 1060816-67-2 | 100mg | $70 | 2026-05-06 | Buy |
| Synthonix | C7614 | 2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine 97.0% | 1060816-67-2 | 250mg | $77 | 2026-05-06 | Buy |
2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine Chemical Properties,Uses,Production
Synthesis
![2-CHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE](/CAS/GIF/335654-06-3.gif)
335654-06-3
74-88-4
![2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine](/CAS2/GIF/1060816-67-2.gif)
1060816-67-2
Step-1: 2-Chloro-7H-pyrrolo[2,3-d]pyrimidine (1 g, 6.5 mmol) was dissolved in acetonitrile (25 mL) at 5°C and sodium hydride (313 mg, 7.8 mmol) was added under stirring. The reaction mixture was warmed to room temperature and stirring was continued for 30 minutes. Subsequently, iodomethane was slowly added at 0 °C and then the reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and washed with acetonitrile (10 mL). The filtrate was concentrated and a portion of the product was obtained by recrystallization from ether. The mother liquor was further concentrated and purified by ISCO system (silica gel column, eluent: dichloromethane/ethyl acetate, 0 to 30% gradient). Combining the recrystallized and column chromatography-purified products, 2-chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine (835 mg, 77% yield) was finally obtained.
References
[1] Patent: WO2016/171755, 2016, A1. Location in patent: Paragraph 0182
[2] Patent: US2010/298334, 2010, A1. Location in patent: Page/Page column 44
[3] Patent: WO2014/100695, 2014, A1. Location in patent: Paragraph 00378
2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| KARMEL TECHNOLOGY (HK) CO.,LIMITED | +8618795957998 | karmelhk@126.com | CHINA | 2886 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +8618118463618 | sales1@artkmedchem.com | China | 39021 | 58 |
| Compound Net Biotechnology Inc. | +8615303909093 | sales@compound-net.com | China | 2914 | 58 |
