ChemicalBook >> CAS DataBase List >>2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester
2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester
![2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester Structure](CAS/GIF/1280210-79-8.gif)
- CAS No.
- 1280210-79-8
- Chemical Name:
- 2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester
- Synonyms
- tert-butyl 2,6-dihydropyrrolo[3,4-c]pyrazole-5(4H)-carboxylate;Omarigliptin Impurity 9;tert-butyl pyrrolo[3,4-c]pyrazole-5(2H,4H,6H)-carboxylate;tert-butyl 4,6-dihydro-2H-pyrrolo[3,4-c]pyrazole-5-carboxylate;5-tert-Butoxycarbonyl-1,4,5,6-tetrahydropyrrolo-[3,4-c]-pyra...;tert-butyl 4,6-dihy dropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate;2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester;2,6-Dihydropyrrolo[3,4-c]pyrazole-5(4H)-carboxylic acid 1,1-dimethylethyl ester;Pyrrolo[3,4-c]pyrazole-5(4H)-carboxylic acid, 2,6-dihydro-, 1,1-dimethylethyl ester
- CBNumber:
- CB82629665
- Molecular Formula:
- C10H15N3O2
- Molecular Weight:
- 209.24
- MDL Number:
- MFCD22565651
- MOL File:
- 1280210-79-8.mol
Last updated:2026-05-28 05:38:48
| Product description | Number | Pack Size | Price |
| 2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester | 161154 | 1.00g | $269 |
| tert-Butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate 97% | B53131 | 100mg | $23 |
| tert-Butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate 97% | B53131 | 250mg | $27 |
| tert-Butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate 97% | B53131 | 1g | $29 |
| tert-Butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate 97% | B53131 | 5g | $50 |
| Boiling point | 366.0±42.0 °C(Predicted) |
|---|---|
| Density | 1.243±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 14.52±0.20(Predicted) |
| Appearance | Off-white to light yellow Solid |
| InChI | InChI=1S/C10H15N3O2/c1-10(2,3)15-9(14)13-5-7-4-11-12-8(7)6-13/h4H,5-6H2,1-3H3,(H,11,12) |
| InChIKey | IBUNCTVDGYIKAP-UHFFFAOYSA-N |
| SMILES | N1C=C2CN(C(OC(C)(C)C)=O)CC2=N1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 |
2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 161154 | 2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester | 1280210-79-8 | 1.00g | $269 | 2026-05-18 | Buy |
| Synthonix | B53131 | tert-Butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate 97% | 1280210-79-8 | 100mg | $23 | 2026-05-06 | Buy |
| Synthonix | B53131 | tert-Butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate 97% | 1280210-79-8 | 250mg | $27 | 2026-05-06 | Buy |
| Synthonix | B53131 | tert-Butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate 97% | 1280210-79-8 | 1g | $29 | 2026-05-06 | Buy |
| Synthonix | B53131 | tert-Butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate 97% | 1280210-79-8 | 5g | $50 | 2026-05-06 | Buy |
2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester Chemical Properties,Uses,Production
Synthesis
157327-42-9
![2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester](/CAS/GIF/1280210-79-8.gif)
1280210-79-8
The reaction of tert-butyl 3-((dimethylamino)methylene)-4-oxopyrrolidine-1-carboxylate (1 g, 4.16 mmol, 1.00 eq.) with hydrazine hydrate (340 mg, 6.79 mmol, 1.63 eq.) in ethanol (10 mL) was stirred for 5 hours at room temperature. Upon completion of the reaction, the mixture was concentrated under vacuum and the resulting residue was purified by silica gel column chromatography with ethyl acetate/petroleum ether as eluent (gradient elution from 1:5 to 1:2). The final product was 250 mg of tert-butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate in 29% yield as a yellow solid. The product was analyzed by LC/MS (Method C, ESI): retention time RT = 1.30 min, mass spectrum m/z ~ 210.0 [M + H]+.
References
[1] Patent: WO2013/127267, 2013, A1. Location in patent: Page/Page column 97; 98
[2] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 19, p. 5361 - 5366
[3] Patent: EP3144310, 2017, A1
2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester Suppliers
Global( 113)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Shanghai Yingrui Biopharma Co.,Ltd | 21-33585366 | export01@shyrchem.com | CHINA | 1319 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Shanghai Boc Chemical Co., Ltd. | 021-34975602; +8618721111801 | shangli@bocchem.com | China | 138 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| JIAXING REGEN CHEMICAL CO.,LTD | +8613385739570 | regen_chemical1@163.com | China | 226 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 | info@afinechem.com | China | 15083 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9539 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
View Lastest Price from 2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester pictures](https://img.chemicalbook.com/ProductImageEN/2020-1/Small/ae2eaabd-0665-4f08-8b51-26d3f57c0f15.jpg) |
2020-01-03 | 2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester
1280210-79-8
|
$1.00 | 1KG | 99% | 10000KGS | Career Henan Chemical Co |
-
- 2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester
1280210-79-8
- $1.00
- 99%
- Career Henan Chemical Co
2,6-Dihydro-4H-pyrrolo[3,4-c]pyrazole-5-carboxylic acid tert-butyl ester
tert-butyl 4,6-dihy
dropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate
Pyrrolo[3,4-c]pyrazole-5(4H)-carboxylic acid, 2,6-dihydro-, 1,1-dimethylethyl ester
tert-butyl pyrrolo[3,4-c]pyrazole-5(2H,4H,6H)-carboxylate
2,6-Dihydropyrrolo[3,4-c]pyrazole-5(4H)-carboxylic acid 1,1-dimethylethyl ester
Omarigliptin Impurity 9
tert-butyl 4,6-dihydro-2H-pyrrolo[3,4-c]pyrazole-5-carboxylate
5-tert-Butoxycarbonyl-1,4,5,6-tetrahydropyrrolo-[3,4-c]-pyra...
tert-butyl 2,6-dihydropyrrolo[3,4-c]pyrazole-5(4H)-carboxylate
1280210-79-8
