ChemicalBook >> CAS DataBase List >>(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride

(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride

(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride structure

CAS No.: 35202-55-2

Chemical Name:: (3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride

Synonyms: Ivabradine Impurity 9 HCl;Ivabradine Impurity 28 HCl;(3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl)methanamine;3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-methanamine Hydrochloride;(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride;3,4-Dimethoxy-Bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine hydrochloride (1:1)

CBNumber:: CB83052277

Molecular Formula:: C11H16ClNO2

Molecular Weight:: 229.70324

MDL Number:: MFCD28038688

MOL File:: 35202-55-2.mol

Last updated:2025-07-24 18:13:45

Product description	Number	Pack Size	Price
(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride	312416	250.00mg	$71
(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride	312416	1.00g	$130
(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride	312416	5.00g	$633
(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride 97%	D55513	100mg	$50
(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride 97%	D55513	250mg	$70

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(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride Properties

storage temp.	Sealed in dry,Room Temperature
Appearance	White to light yellow Solid
FDA UNII	322VUN7K2C

(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride price More Price(25)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Matrix Scientific	312416	(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride	35202-55-2	250.00mg	$71	2026-05-19	Buy
Matrix Scientific	312416	(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride	35202-55-2	1.00g	$130	2026-05-19	Buy
Matrix Scientific	312416	(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride	35202-55-2	5.00g	$633	2026-05-19	Buy
Synthonix	D55513	(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride 97%	35202-55-2	100mg	$50	2026-05-06	Buy
Synthonix	D55513	(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride 97%	35202-55-2	250mg	$70	2026-05-06	Buy

Product number	Packaging	Price	Buy
312416	250.00mg	$71	Buy
312416	1.00g	$130	Buy
312416	5.00g	$633	Buy
D55513	100mg	$50	Buy
D55513	250mg	$70	Buy

(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride Chemical Properties,Uses,Production

Synthesis

35202-54-1

(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride

35202-55-2

General procedure for the synthesis of (3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-dien-7-yl)methanamine hydrochloride from 4,5-dimethoxy-1-cyanobenzocyclobutane: reference to EP 0 534 859 Step 1: Preparation of 3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-amine hydrochloride. To a solution of 25 g of 3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile dissolved in 250 ml of tetrahydrofuran (THF) at room temperature was added slowly and dropwise 312 ml of borane-THF complex solution with continuous stirring for 12 hours. Subsequently, 200 mL of ethanol was added and stirring was continued for 1 hour. 100 ml of a 3.3 N solution of ethyl ether hydrochloride was added slowly and dropwise. Eventually 27.7 g of the target product was obtained in 90% yield with a melting point of 205°C.

References

[1] Patent: US2014/107334, 2014, A1. Location in patent: Paragraph 0052-0055
[2] Patent: US2014/128598, 2014, A1. Location in patent: Paragraph 0044-0047
[3] Patent: US2014/163220, 2014, A1. Location in patent: Paragraph 0040-0043

(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride synthesis

Synthesis of (3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride from 4,5-Dimethoxy-1-cyanobenzocyclobutane

(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride Preparation Products And Raw materials

Raw materials

(E)-3-(3,4-dimethoxyphenyl)acrylonitrile 3-(3,4-Dimethoxyphenyl)propanenitrile 4,5-Dimethoxy-1-cyanobenzocyclobutane 3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE 2-Bromo-4,5-Dimethoxybenzyl Bromide

4-Bromoveratrole 3,4-Dimethoxybenzyl alcohol Veratraldehyde BORANE THF Tetrahydrofuran

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Preparation Products

(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride Suppliers

Global( 36)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-173 9270 1263	1057@dideu.com	China	3997	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
Aladdin Scientific		tp@aladdinsci.com	United States	52923	58
Shanghai Likang New Materials Co., Limited	+86-16631818819 +86-17736933208	3684455296@qq.com	China	9300	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
Adamas Reagent, Ltd.	400-6009262 15618770481	yhx@titansci.com	China	14100	59
Beijing YiboYuntian Technology Co., Ltd.	13811826434	lichen13811826434@126.com	China	681	58
Wuxi AppTec	022-59987777 13552403979	jia_guoqiang@wuxiapptec.com	China	22345	58
Aikon International Limited	025-58859352 19370895928	dt3@aikonchem.com	China	15491	58

Supplier	Advantage
Shaanxi Dideu Medichem Co. Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Aladdin Scientific	58
Shanghai Likang New Materials Co., Limited	58
Amadis Chemical Company Limited	58
Adamas Reagent, Ltd.	59
Beijing YiboYuntian Technology Co., Ltd.	58
Wuxi AppTec	58
Aikon International Limited	58

View Lastest Price from (3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-08-17	(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride 35202-55-2	$1.00	1KG	99%	20T	Shaanxi Dideu Medichem Co. Ltd

(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride
35202-55-2
$1.00
99%
Shaanxi Dideu Medichem Co. Ltd

(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride Spectrum

(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride(35202-55-2)¹HNMR

35202-55-2((3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride)Related Search:

Ivabradine Impurity 5 3-(3-hydroxypropyl)-7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one Ivabradine IMpurity 7-DeMethyl Ivabradine 2H-3-Benzazepin-2-one, 3-[3-[[[(7R)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3-dihydro-7,8-dimethoxy-, ethanedioate (1:1)

Ivabradine impurity (Br) Ivabradine Impurity 1 Hydrochloride (1S)-4, 5-dimethoxyl-1 -(ethoxycarbonyl aminomethyl) -benzocyclobutane 1616710-52-1 Ivabradine Impurity 1 Hydrochloride

INDEX NAME NOT YET ASSIGNED 1204612-29-2 Dehydro Ivabradine Oxalate 7,8-Dimethoxy-3-(3-iodopropyl)-1,3-dihydro-2H-3-benzazepin-2-one 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one

(Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one 4,5-Dimethoxy-1-cyanobenzocyclobutane (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride

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(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methanamine hydrochloride (3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl)methanamine 3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-methanamine Hydrochloride 3,4-Dimethoxy-Bicyclo[4.2.0]octa-1,3,5-triene-7-methanamine hydrochloride (1:1) Ivabradine Impurity 28 HCl Ivabradine Impurity 9 HCl 35202-55-2

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