Z-SER(BZL)-OH
- CAS No.
- 20806-43-3
- Chemical Name:
- Z-SER(BZL)-OH
- Synonyms
- Cbz-Ser(Bzl);Z-SER(BZL)-OH;CBZ-SER(BZL)-OH;Z-L-Ser(Bzl)-OH;Z-SERINE(BZL)-OH;Cbz-L-Ser(Bzl)-OH;Z-Ser(Bzl)-OH,95 %;Z-O-BENZYL-L-SERINE;Cbz -O-benzyl-L-serine;Z-O-benzyl-L-serine99%
- CBNumber:
- CB8346456
- Molecular Formula:
- C18H19NO5
- Molecular Weight:
- 329.35
- MDL Number:
- MFCD00022029
- MOL File:
- 20806-43-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| CARBOBENZYLOXY-O-BENZYL-L-SERINE AldrichCPR | S776963 | 1 unit | $121 |
| CARBOBENZYLOXY-O-BENZYL-L-SERINE AldrichCPR | S776963 | 50MG | $110 |
| Cbz-Ser(bzl)-OH | FC37793 | 5g | $163.3 |
| Cbz-Ser(bzl)-OH | FC37793 | 10g | $290.3 |
| Cbz-Ser(bzl)-OH | FC37793 | 25g | $453.75 |
| More product size | |||
| Boiling point | 537.1±50.0 °C(Predicted) |
|---|---|
| Density | 1.253±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 3.51±0.10(Predicted) |
| color | White to off-white |
| optical activity | Consistent with structure |
| Water Solubility | Slightly soluble in water. |
| CAS DataBase Reference | 20806-43-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 | |||||||||
| NFPA 704 |
|
Z-SER(BZL)-OH price More Price(64)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S776963 | CARBOBENZYLOXY-O-BENZYL-L-SERINE AldrichCPR | 20806-43-3 | 1 unit | $121 | 2026-04-30 | Buy |
| Sigma-Aldrich | S776963 | CARBOBENZYLOXY-O-BENZYL-L-SERINE AldrichCPR | 20806-43-3 | 50MG | $110 | 2024-03-01 | Buy |
| Biosynth | FC37793 | Cbz-Ser(bzl)-OH | 20806-43-3 | 5g | $163.3 | 2026-06-04 | Buy |
| Biosynth | FC37793 | Cbz-Ser(bzl)-OH | 20806-43-3 | 10g | $290.3 | 2026-06-04 | Buy |
| Biosynth | FC37793 | Cbz-Ser(bzl)-OH | 20806-43-3 | 25g | $453.75 | 2026-06-04 | Buy |
Z-SER(BZL)-OH Chemical Properties,Uses,Production
Uses
Cbz-Ser(Bzl)-OH is used in preparation of Aminoamide derivatives as anticancer agents.
Synthesis
4726-96-9
31139-36-3
20806-43-3
At room temperature, O-benzyl-L-serine (25.0 g, 128 mmol) was dissolved in a mixed solvent of water (200 mL) and dioxane (100 mL) and sodium carbonate (7.46 g, 70 mmol) was added. Subsequently, a solution of dibenzyl dicarbonate (36.1 g, 126 mmol) in dioxane (100 mL) was slowly added dropwise and the reaction mixture was stirred at room temperature for 18 hours. Upon completion of the reaction, the dioxane was removed by vacuum evaporation and the remaining aqueous phase was extracted with ether. The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under vacuum to give the crude product N-benzyloxycarbonyl-O-benzyl-L-serine (39.57 g, 95% yield) as a white solid, which was finally purified by washing with hexane.
References
[1] Liebigs Annalen der Chemie, 1994, # 6, p. 641 - 644
[2] Patent: US5030654, 1991, A
[3] Patent: EP274234, 1991, B1
Z-SER(BZL)-OH Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| GL Biochem(Binhai) Ltd. | +86-021-61263370 +8615301650015 | wuqiuyan@glschina.com | China | 2975 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +8619945049750 | info@finetechnology-ind.com | China | 9539 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| Hangzhou Go Top Peptide Biotech | 0571-88211921 | sales1@gotopbio.com | CHINA | 2609 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49962 | 58 |
View Lastest Price from Z-SER(BZL)-OH manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-02-01 | Z-SER(BZL)-OH
20806-43-3
|
$3.00 | 1KG | 98% | 100KG | Career Henan Chemical Co |
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- Z-SER(BZL)-OH
20806-43-3
- $3.00
- 98%
- Career Henan Chemical Co
