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ChemicalBook >> CAS DataBase List >>1,1-Diethoxybutane

1,1-Diethoxybutane

CAS No.
3658-95-5
Chemical Name:
1,1-Diethoxybutane
Synonyms
Butane, 1,1-diethoxy-;1,1-DIETHOXYBUTANE;Butanal diethyl acetal;butyraldehyde ethyl acetal;BUTRALDEHYDE DIETHYL ACETAL;Butylaldehyde diethyl acetal;butylaldehydediethylaldehyde;BUTYRALDEHYDE DIETHYL ACETAL;n-Butyraldehyde diethyl acetal;BUTYRALDEHYDE DIETHYLACETAL, 97+%
CBNumber:
CB8388533
Molecular Formula:
C8H18O2
Molecular Weight:
146.23
MDL Number:
MFCD00038316
MOL File:
3658-95-5.mol
MSDS File:
SDS
Last updated:2026-05-28 04:33:23
Product description Number Pack Size Price
1,1-Diethoxybutane 95% AA00BXQR 1g $74
1,1-Diethoxybutane 98%(GC) AA00BXQR 5g $109
1,1-Diethoxybutane 98%(GC) AA00BXQR 25g $377
Butyraldehyde diethyl acetal 97% JK476046 5g $25
Butyraldehyde diethyl acetal 97% JK476046 25g $81
More product size

1,1-Diethoxybutane Properties

Boiling point 143°C/760mmHg
Density 0.829 g/mL at 20 °C
refractive index n20/D1.396
FLAVIS Number 06.061 | 1,1-Diethoxybutane
Flash point 30 °C
storage temp. Flammables area
form Liquid
color Clear colorless
BRN 1697910
LogP 2.041 (est)
NIST Chemistry Reference Butane, 1,1-diethoxy-(3658-95-5)
EPA Substance Registry System Butane, 1,1-diethoxy- (3658-95-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H315-H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  10-36/38
Safety Statements  26-37/39-16
RIDADR  UN 1993C 3 / PGIII
WGK Germany  3
TSCA  TSCA listed
HS Code  29329990
NFPA 704
3
2 0

1,1-Diethoxybutane price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA00BXQR 1,1-Diethoxybutane 95% 3658-95-5 1g $74 2026-05-28 Buy
aablocks AA00BXQR 1,1-Diethoxybutane 98%(GC) 3658-95-5 5g $109 2026-05-28 Buy
aablocks AA00BXQR 1,1-Diethoxybutane 98%(GC) 3658-95-5 25g $377 2026-05-28 Buy
Frontier Specialty Chemicals JK476046 Butyraldehyde diethyl acetal 97% 3658-95-5 5g $25 2021-12-16 Buy
Frontier Specialty Chemicals JK476046 Butyraldehyde diethyl acetal 97% 3658-95-5 25g $81 2021-12-16 Buy
Product number Packaging Price Buy
AA00BXQR 1g $74 Buy
AA00BXQR 5g $109 Buy
AA00BXQR 25g $377 Buy
JK476046 5g $25 Buy
JK476046 25g $81 Buy

1,1-Diethoxybutane Chemical Properties,Uses,Production

Chemical Properties

Clear colorless liquid

Uses

1,1-Diethoxybutane-d10 is a deuterated labeled 1,1-Diethoxybutane[1].

Preparation

To a three-necked flask equipped with an air-tight mechanical stirrer, dropping funnel, reflux condenser, and drying tube, are added 3.0 gm (1.25 gm-atom) magnesium turnings, 50 ml of dry ether, and a small crystal of iodine. Then 5 gm of rt-butyl bromide is added dropwise until 171.0 gm (1.25 mole) has been added. The reaction takes about ½ - l h r if the reaction mixture is cooled. The solution is refluxed for ½ hr, cooled to 50°C, and then 148 gm (1.0 mole) of triethyl orthoformate is added dropwise over a ½-hr period. The reaction mixture is refluxed for 16 hr, crushed ice added to decompose the excess Grignard reagent, the ether separated and washed with water. The water layer is added to a separatory funnel containing 200 ml of ether, treated with acetic acid to pH 7.0, shaken, and the ether separated. The latter ether layer is washed with 10% aqueous sodium carbonate, water, and dried. The latter water layer is extracted twice again with ether (200 ml). The combined ether layers are dried over potassium carbonate and fractionated to afford 128 gm (80%), b.p. 143°-144°.
Preparation of n-Butyraldehyde Diethyl Acetal

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110

123-72-8
122-51-0
3658-95-5
Synthesis of 1,1-Diethoxybutane from Butyraldehyde and Triethyl orthoformate
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View Lastest Price from 1,1-Diethoxybutane manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,1-Diethoxybutane pictures 2024-07-15 1,1-Diethoxybutane
3658-95-5
$1.00 1KG 99% 20t Shaanxi Dideu Medichem Co. Ltd

1,1-Diethoxybutane Spectrum

Butylaldehyde diethyl acetal n-Butyraldehyde diethyl acetal BUTYRALDEHYDE DIETHYL ACETAL BUTRALDEHYDE DIETHYL ACETAL butyraldehyde ethyl acetal BUTYRALDEHYDE DIETHYLACETAL, 97+% Butanal diethyl acetal 1,1-DIETHOXYBUTANE butylaldehydediethylaldehyde Butane, 1,1-diethoxy- 3658-95-5
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