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(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID

(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID structure

CAS No.: 261165-05-3

Chemical Name:: (+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID

Synonyms: BOC-(1S,3R)-3-Aminocyclopentanecarboxylic acid;(+)-(1S,3R)-N-Boc-b-homocycloleucine;(+)-(1S,3R)-N-Boc-β-Homocycloleucine;(+)-(1S,3R)-N-BOC-BETA-HOMOCYCLOLEUCINE;(1S,3R)-Boc-3-aminocyclopentane-1carboxylicaci;(1S,3R)-Boc-3-aminocyclopentane-1 carboxylic acid;(1R,3S)-N-BOC-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID;(1S,3R)-3-[N-BOC-Amino]cyclopentane-carboxylic acid;(1S,3R)-(+)-3-(BOC-AMINO)CYCLOPENTANECARBOXYLIC ACID;(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID

CBNumber:: CB8441571

Molecular Formula:: C11H19NO4

Molecular Weight:: 229.27

MDL Number:: MFCD01320857

MOL File:: 261165-05-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:22:29

Product description	Number	Pack Size	Price
(1S,3R)-3-(tert-Butoxycarbonylamino)cyclopentanecarboxylic Acid >95.0%(GC)(T)	B4397	200mg	$105
BOC-(1S,3R)-3-Aminocyclopentanecarboxylic acid ≥95%	11406	50mg	$94
BOC-(1S,3R)-3-Aminocyclopentanecarboxylic acid ≥95%	11406	50mg	$85
(-)-(1R,3S)-N-Boc-1-Aminocyclopentane-3-carboxylic Acid	412591	50mg	$319
(-)-(1R,3S)-N-Boc-1-Aminocyclopentane-3-carboxylic Acid	412591	100mg	$425

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(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID Properties

Melting point	35-49 °C
Boiling point	371.18°C (rough estimate)
Density	1.1482 (rough estimate)
refractive index	1.4490 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	slightly sol. in Methanol
form	Powder or Chunks
pka	4.62±0.40(Predicted)
color	White
optical activity	[α]/D +16.0±1°, c = 1% in methanol
Major Application	peptide synthesis
InChI	InChI=1S/C11H19NO4/c1-11(2,3)16-10(15)12-8-5-4-7(6-8)9(13)14/h7-8H,4-6H2,1-3H3,(H,12,15)(H,13,14)/t7-,8+/m0/s1
InChIKey	RNJQBGXOSAQQDG-JGVFFNPUSA-N
SMILES	[C@H]1(C(O)=O)CC[C@@H](NC(OC(C)(C)C)=O)C1
UNSPSC Code	12352202
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P305+P351+P338

PPE

Eyeshields, Gloves, type N95 (US)

Hazard Codes

Safety Statements

22-24/25

WGK Germany

HazardClass

IRRITANT

HS Code

29223900

Storage Class

13 - Non Combustible Solids

NFPA 704

	0
0		0

(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID price More Price(98)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	B4397	(1S,3R)-3-(tert-Butoxycarbonylamino)cyclopentanecarboxylic Acid >95.0%(GC)(T)	261165-05-3	200mg	$105	2024-03-01	Buy
Cayman Chemical	11406	BOC-(1S,3R)-3-Aminocyclopentanecarboxylic acid ≥95%	261165-05-3	50mg	$94	2026-04-30	Buy
Cayman Chemical	11406	BOC-(1S,3R)-3-Aminocyclopentanecarboxylic acid ≥95%	261165-05-3	50mg	$85	2024-03-01	Buy
Usbiological	412591	(-)-(1R,3S)-N-Boc-1-Aminocyclopentane-3-carboxylic Acid	261165-05-3	50mg	$319	2026-06-03	Buy
Usbiological	412591	(-)-(1R,3S)-N-Boc-1-Aminocyclopentane-3-carboxylic Acid	261165-05-3	100mg	$425	2026-06-03	Buy

Product number	Packaging	Price	Buy
B4397	200mg	$105	Buy
11406	50mg	$94	Buy
11406	50mg	$85	Buy
412591	50mg	$319	Buy
412591	100mg	$425	Buy

(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID Chemical Properties,Uses,Production

Chemical Properties

white powder or chunks

Uses

(-)-(1R,3S)-N-Boc-1-Aminocyclopentane-3-carboxylic Acid is a reagent used in the synthesis of 3-substituted aminocyclopentanes as potent NR2B subtype-sellective NMDA antagonists in the treatment of neuropathic pain and Parkinson’s.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

(+)-(1R,4S)-N-BOC-4-AMINOCYCLOPENT-2-ENECARBOXYLIC ACID

151907-80-1

(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID

261165-05-3

The general procedure for the synthesis of (1S,3R)-3-((tert-butoxycarbonyl)amino)cyclopent-2-enecarboxylic acid using (1R,4S)-4-((tert-butoxycarbonyl)amino)cyclopent-2-enecarboxylic acid as a starting material was as follows: (1R,4S)-4-((tert-butoxycarbonyl)amino)cyclopent-2-enecarboxylic acid (230 g, 1.0 mol) prepared in step A was hydrogenated with 10% Pd/ C catalyst (5.0 g) in 500 mL of methanol and hydrogenated on a Parr shaker at 50 psi hydrogen pressure for 1 hour. Upon completion of the reaction, the catalyst was removed by filtration followed by evaporation of the filtrate to remove the solvent. The resulting residue was dissolved in dichloromethane and dried by adding anhydrous sodium sulfate. After filtration again, the filtrate was evaporated and dried under vacuum to afford (1S,3R)-3-((tert-butoxycarbonyl)amino)cyclopentanecarboxylic acid as a light yellow solid (230 g, 99% yield). Analyzed by LC-MS, the calculated value of [M+H+] for C11H19NO4 was 230 and the measured value was 230, which was as expected.

References

[1] Patent: WO2004/76411, 2004, A2. Location in patent: Page 28
[2] Patent: WO2003/93231, 2003, A2. Location in patent: Page/Page column 56
[3] Patent: US2007/155731, 2007, A1. Location in patent: Page/Page column 27; 36
[4] Patent: WO2005/110409, 2005, A2. Location in patent: Page/Page column 30
[5] Patent: WO2005/75426, 2005, A1. Location in patent: Page/Page column 28

(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID synthesis

Synthesis of (+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID from Di-tert-butyl dicarbonate and (1S,3R)-3-Aminocyclopentanecarboxylic acid

(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 3-oxo-, 1,1-dimethylethyl ester, (1R,4S)- (1S,4R)-tert-butyl 3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate 2-Azabicyclo[2.2.1]heptan-3-one (1R,4S)-4-Aminocyclopent-2-enecarboxylic acid (1S,3R)-Methyl 3-[(tert-butoxycarbonyl)-amino]cyclopentanecarboxylate

(1S,3R)-3-Aminocyclopentanecarboxylic acid (+)-(1R,4S)-N-BOC-4-AMINOCYCLOPENT-2-ENECARBOXYLIC ACID Di-tert-butyl dicarbonate 2-Azabicyclo[2.2.1]hept-5-en-3-one Acetic anhydride

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Preparation Products

(-)-(1R,3S)-N-Boc-3-Aminocyclopentanecarboxylic acid methyl (1R,3R)-3-{[(tert-butoxy)carbonyl]amino}cyclopentane-1-carboxylate

(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID Suppliers

Global( 145)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	21169	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58
changzhou huayang technology co., ltd	+8615250961469	2571773637@qq.com	China	9653	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43333	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Fuxin Pharmaceutical	58
Dideu Industries Group Limited	58
Nextpeptide Inc	58
changzhou huayang technology co., ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
HANGZHOU LEAP CHEM CO., LTD.	58

View Lastest Price from (+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-08-02	(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID 261165-05-3	$1.00	1KG	95-99%	500kg/month	Career Henan Chemical Co

(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID
261165-05-3
$1.00
95-99%
Career Henan Chemical Co

(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID Spectrum

(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID(261165-05-3)¹HNMR (+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID(261165-05-3)¹HNMR

261165-05-3((+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID)Related Search:

BOC-1,3-CIS-ACHC-OH (-)-(1S,4R)-N-BOC-4-AMINOCYCLOPENT-2-ENECARBOXYLIC ACID 3-AMINOCYCLOPENTANECARBOXYLIC ACID BOC-1-AMINOCYCLOPENTANECARBOXYLIC ACID (1R,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID 95% (98% E.E.)

BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID (1R,2S,4S)-N-BOC-1-AMINO-2-HYDROXYCYCLOPENTANE-4-CARBOXYLIC ACID METHYL ESTER (+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID (-)-(1R,3S)-N-Boc-3-Aminocyclopentanecarboxylic acid 4-[(TERT-BUTOXYCARBONYL)AMINO]BICYCLO[2.1.1]HEXANE-1-CARBOXYLIC ACID

(1R,2R,4S)-N-BOC-1-AMINO-2-HYDROXYCYCLO-PENTANE-4-CARBOXYLIC ACID METHYL ESTER C(1S,2S,3R,4R)-3-(1-ACETYLAMINO-2-ETHYLBUYL)-4-TUBOXYCARBONYL-AMINO-2-METHYLCYCLOPENTANE CARBOXYLIC ACID METHYL ESTER

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(1S,3R)-(+)-3-Aminocyclopentane-1-carboxylic acid, N-BOC protected (+)-(1S,3R)-N-Boc-3-aMinocyclopentanecarboxylic acidacid (1S,3R)-3-((tert-Butoxycarbonyl)aMino)cyclopentanecarboxylic acid Cis(1S,3R)-3-((tert-butoxycarbonyl)aMino) cyclopentanecarboxylic acid (1S,3R)-(+)-3-(Boc-amino)cyclopentanecarboxylic acid >=96.0% (HPLC) (1S,3R)-3-(tert-Butoxycarbonylamino)cyclopentanecarboxylic Acid Cyclopentanecarboxylicacid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, (1S,3R)- (+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID (+)-(1S,3R)-N-BOC-BETA-HOMOCYCLOLEUCINE (1S,3R)-(+)-3-(BOC-AMINO)CYCLOPENTANECARBOXYLIC ACID (1R,3S)-N-TERT-BUTOXYCARBONYL-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID (-)-(1R,3S)-N-ALPHA-T-BUTOXYCARBONYL-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID (+)-(1R,3S)-N-BOC-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID (1R,3S)-N-BOC-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID (1R,3S)-N-boc-1-Aminocyclopentane-3-carboxylicacid(e.e.) (1S,3R)-(+)-3-Aminocyclopentanecarboxylic acid, N-BOC protected Cis-3-(N-Tert-Butoxycarbonylamino)Cyclopentanecarboxylic Acid (+)-(1S,3R)-N-Boc-b-homocycloleucine (1R,3s)-N-Boc-1-aminocyclopentane-3-carboxylic acid, 95%, ee:98% (1R,3S)-N-BOC-1-Aminocyclopentane-3-carboxylic acid, 98% ee (1R,3S)-N-BOC-1-Aminocyclopentane-3-carboxylic acid,95%,98% ee (1R,3S)-N-BOC-1-Aminocyclopentane-3-carboxylic acid(1R,3S)-N-tert-Butoxycarbonyl-1-aminocyclopentane-3-carboxylic acid (1S,3R)-Boc-3-aminocyclopentane-1 carboxylic acid (1S,3R)-(+)-3-[(tert-Butoxycarbonyl)amino]cyclopentane-1-carboxylic acid (+)-(1S,3R)-N-Boc-3-aminocyclopentanecarboxylicacidacid (+)-(1S,3R)-N-(Tert-Butoxy)Carbonyl 3-Aminocyclopentanecarboxylic acid (1S,3R)-(+)-3-Aminocyclopentane-1-carboxylic acid, N-BOC protected 97% (1S,3R)-3-(tert-Butoxycarbonylamino)cyclopentanecarboxylic Acid > (1S,3R)-(+)-3-(Boc-amino)cyclopentanecarboxylicacid,95% (1S,3R)-Boc-3-aminocyclopentane-1carboxylicaci (+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID USP/EP/BP (+)-(1S,3R)-3-[(t-Butoxycarbonyl)amino]cyclopentanecarboxylic acid BOC-(1S,3R)-3-Aminocyclopentanecarboxylic acid (-)-(1R,3s)-n-boc-1-aminocyclopentane-3-carboxylic acid (+)-(1S,3R)-N-Boc-β-Homocycloleucine (1S,3R)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]cyclopentanecarboxylic acid (+)-(1S,3R)-N-Fmoc3-aminocyclopentanecarboxylicacidacid (1S,3R)-(+)-3-(Boc-amino)cyclopentanecarboxylic acid (+)-(1S,3R)-N-Boc-3-Aminocyclopentanecarboxylic acid (1S,3R)-3-[N-BOC-Amino]cyclopentane-carboxylic acid 261165-05-3 Beta-Amino Acids Peptide Synthesis Specialty Synthesis Unnatural Amino Acid Derivatives Unnatural Amino Acid Derivatives Unusual amino acids API intermediates Beta-Amino Acids Peptide Synthesis

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