2-Chloro-5-hydroxypyridine
- CAS No.
- 41288-96-4
- Chemical Name:
- 2-Chloro-5-hydroxypyridine
- Synonyms
- 6-CHLOROPYRIDIN-3-OL;2-Chloro-5-Pyridol;2-Chloropyridin-5-ol;2-CHLORO-5-PYRIDINOL;6-Chloro-3-pyridinol;6-chloropyridine-3-ol;3-PYRIDINOL, 6-CHLORO-;2-Chloro-5-hydropyridine;2-CHLORO-5-HYDROXYPYRIDINE;3-Pyridinol,6-chloro-(9CI)
- CBNumber:
- CB8695961
- Molecular Formula:
- C5H4ClNO
- Molecular Weight:
- 129.54
- MDL Number:
- MFCD00234050
- MOL File:
- 41288-96-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Chloro-5-hydroxypyridine >97.0%(GC)(T) | C2271 | 5g | $140 |
| 2-Chloro-5-hydroxypyridine 99+% (HPLC) ≥99%(HPLC) | 230166 | 1g | $159 |
| 2-Chloro-5-hydroxypyridine 99+% (HPLC) ≥99%(HPLC) | 230166 | 5g | $206 |
| 2-Chloro-5-hydroxypyridine 99+% (HPLC) ≥99%(HPLC) | 230166 | 25g | $375 |
| 2-Chloro-5-hydroxypyridine | FC00525 | 0.1kg | $150 |
| More product size | |||
| Melting point | 155-158°C |
|---|---|
| Boiling point | 351.9±22.0 °C(Predicted) |
| Density | 1.392±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | powder to crystal |
| pka | 8.69±0.10(Predicted) |
| color | Light yellow to Brown |
| InChI | InChI=1S/C5H4ClNO/c6-5-2-1-4(8)3-7-5/h1-3,8H |
| InChIKey | KVCOOWROABTXDJ-UHFFFAOYSA-N |
| SMILES | C1=NC(Cl)=CC=C1O |
| CAS DataBase Reference | 41288-96-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | T,Xi,Xn | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36/37/39-36-37 | |||||||||
| HazardClass | IRRITANT | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
2-Chloro-5-hydroxypyridine price More Price(99)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C2271 | 2-Chloro-5-hydroxypyridine >97.0%(GC)(T) | 41288-96-4 | 5g | $140 | 2026-04-30 | Buy |
| Usbiological | 230166 | 2-Chloro-5-hydroxypyridine 99+% (HPLC) ≥99%(HPLC) | 1g | $159 | 2026-06-03 | Buy | |
| Usbiological | 230166 | 2-Chloro-5-hydroxypyridine 99+% (HPLC) ≥99%(HPLC) | 5g | $206 | 2026-06-03 | Buy | |
| Usbiological | 230166 | 2-Chloro-5-hydroxypyridine 99+% (HPLC) ≥99%(HPLC) | 25g | $375 | 2026-06-03 | Buy | |
| Biosynth | FC00525 | 2-Chloro-5-hydroxypyridine | 41288-96-4 | 0.1kg | $150 | 2026-06-04 | Buy |
2-Chloro-5-hydroxypyridine Chemical Properties,Uses,Production
Uses
2-Chloro-5-hydroxypyridine is an organic intermediate.
Chemical Properties
Light yellow Cryst
Synthesis
188057-24-1
41288-96-4
11B. 6-Chloropyridin-3-yl acetate (11.1 g, 64.7 mmol) from step 11a was dissolved in methanol at room temperature, followed by addition of solid potassium carbonate (4.47 g, 32.4 mmol). The reaction mixture was stirred for 2 hours and the volatiles were removed under reduced pressure. The residue was diluted with ether and water, and the aqueous phase was neutralized to pH 7 by addition of aqueous 1 N hydrochloric acid.The organic and aqueous layers were separated and the aqueous phase was extracted twice with ether. The organic extracts were combined, dried over magnesium sulfate and concentrated to give 2-chloro-5-hydroxypyridine as a white solid (8.03 g, 96% yield): melting point 155 °C; 1H NMR (CD3OD, 300 MHz) δ 7.20-7.28 (m, 2H), 7.88 (m, 1H); mass spectrum (CI/NH3) m/z: 130,132 (M+H) +; 147,149 (M+NH4)+.
References
[1] Patent: US6696439, 2004, B1. Location in patent: Page column 20
[2] Patent: US6001849, 1999, A
[3] Tetrahedron Letters, 2003, vol. 44, # 4, p. 725 - 728
[4] Patent: EP1698626, 2006, A1. Location in patent: Page/Page column 24
[5] Patent: WO2004/72072, 2004, A1. Location in patent: Page 85
2-Chloro-5-hydroxypyridine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
View Lastest Price from 2-Chloro-5-hydroxypyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 2-Chloro-5-hydroxypyridine
41288-96-4
|
$8.90 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-11-18 | 2-Chloro-5-hydroxypyridine
41288-96-4
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2025-04-04 | 2-Chloro-5-hydroxypyridine
41288-96-4
|
1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
|
-
- 2-Chloro-5-hydroxypyridine
41288-96-4
- $8.90
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 2-Chloro-5-hydroxypyridine
41288-96-4
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 2-Chloro-5-hydroxypyridine
41288-96-4
- 98%
- Henan Aochuang Chemical Co.,Ltd.
