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ChemicalBook >> CAS DataBase List >>RHOIFOLIN

RHOIFOLIN

CAS No.
17306-46-6
Chemical Name:
RHOIFOLIN
Synonyms
Apigenin-7-O-rhamnoglucoside;APIGENIN 7-O-NEOHESPERIDOSIDE;C12627;RHOIFOLIN;Rhoifoloside;Rhoifolin-RM;Rhoifolin (15 mg);RHOIFOLIN WITH HPLC;Rhoifolin (Standard);Rhoifolin, 10 mM in DMSO
CBNumber:
CB8725424
Molecular Formula:
C27H30O14
Molecular Weight:
578.52
MDL Number:
MFCD00016773
MOL File:
17306-46-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:48
Product description Number Pack Size Price
Rhoifolin phyproof? Reference Substance PHL83302 10MG $167
Apigenin 7-O-neohesperidoside ≥99.0% (HPLC) 12676 5mg $331
Apigenin 7-O-neohesperidoside ≥99.0% (HPLC) 12676 1mg $77.2
Rhoifolin ≥98% 35583 1mg $32
Rhoifolin ≥98% 35583 5mg $141
More product size

RHOIFOLIN Properties

Melting point 250-265 °C(Solv: ethyl acetate (141-78-6))
Boiling point 916.5±65.0 °C(Predicted)
Density 1.69±0.1 g/cm3(Predicted)
storage temp. 0-6°C
solubility Soluble in methan
form powder
pka 6.11±0.40(Predicted)
color Yellow
biological source synthetic
InChIKey RPMNUQRUHXIGHK-HNTVRLFJNA-N
SMILES C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3cc(O)c4C(=O)C=C(Oc4c3)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O
LogP -0.060 (est)
FDA UNII K86F9AKS2A
UNSPSC Code 41116107
NACRES NA.25

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Safety Statements  24/25
WGK Germany  3
HS Code  29399990
Storage Class 11 - Combustible Solids

RHOIFOLIN price More Price(83)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL83302 Rhoifolin phyproof? Reference Substance 17306-46-6 10MG $167 2026-04-30 Buy
Sigma-Aldrich 12676 Apigenin 7-O-neohesperidoside ≥99.0% (HPLC) 17306-46-6 5mg $331 2025-07-31 Buy
Sigma-Aldrich 12676 Apigenin 7-O-neohesperidoside ≥99.0% (HPLC) 17306-46-6 1mg $77.2 2023-06-20 Buy
Cayman Chemical 35583 Rhoifolin ≥98% 17306-46-6 1mg $32 2026-04-30 Buy
Cayman Chemical 35583 Rhoifolin ≥98% 17306-46-6 5mg $141 2026-04-30 Buy
Product number Packaging Price Buy
PHL83302 10MG $167 Buy
12676 5mg $331 Buy
12676 1mg $77.2 Buy
35583 1mg $32 Buy
35583 5mg $141 Buy

RHOIFOLIN Chemical Properties,Uses,Production

Chemical Properties

Methanol is derived from the dried leaves of Turpinia arguya Seem of the Turpinaceae family.

Uses

antiinflammatory

Uses

Rhoifolin is a flavone, a type of flavonoid, a new natural glycoside of apigenin, has been obtained from the green leaves of Rhus succedanea. Rhoifolin has been shown to be an apigenin-7-rhamnoglucoside. Rhoifolin apparently is identical with the apigenin-7-rhamnoglucoside obtained by the bromination and dehydrobromination of Naringin (N378980).

Definition

ChEBI: Apigenin 7-O-neohesperidoside is an apigenin derivative having an alpha-(1->2)-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety attached to the 7-hydroxy group. It has a role as a metabolite. It is a neohesperidoside, a dihydroxyflavone and a glycosyloxyflavone. It is functionally related to an apigenin.

in vivo

Rhoifolin (12, 24, 30, 36, and 40 mg/kg; PO, for 7 days) has radioprotective effect against radiation-induced decrease of blood platelets and cardiac biochemical lesions in whole body irradiated mice[4].

Animal Model:Swiss albino mice (10 Gy irradiation induced certain haematological and cardiac biochemical abnormalities)[4]
Dosage:12, 24, 30, 36, and 40 mg/kg
Administration:PO, for 7 days
Result:Diminished the toxic effect of radiation by decreasing the level of lipid peroxides measured as malondialdehyde, ameliorating the alterations in nitric oxide, lactate dehydrogenase, creatine kinase in plasma and tissue and the plasma lipid profile.

IC 50

insulin receptor-β; GLUT4; NF-κB; MAPK

10236-47-2
17306-46-6
Synthesis of RHOIFOLIN from Naringin

RHOIFOLIN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 271)Suppliers
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Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3619 58
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Chengdu Biopurify Phytochemicals Ltd. 		+86-28-82633860; +8618080483897 sales@biopurify.com China 4616 58
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19936 58
Shanghai Standard Technology Co., Ltd. 		18502101150 ft-sales@nature-standard.com CHINA 1923 58
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TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32466 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Aktin Chemicals, Inc. 		028-85159085 info@aktinchem.com CHINA 1025 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58

View Lastest Price from RHOIFOLIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Rhoifolin pictures 2023-02-24 Rhoifolin
17306-46-6
 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
RHOIFOLIN pictures 2019-07-06 RHOIFOLIN
17306-46-6
 $1.00 1KG 99% Career Henan Chemical Co
  • Rhoifolin pictures
  • Rhoifolin
    17306-46-6
  • $0.00
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
  • RHOIFOLIN pictures
  • RHOIFOLIN
    17306-46-6
  • $1.00
  • 99%
  • Career Henan Chemical Co

RHOIFOLIN Spectrum

APIGENIN-7-NEOHESPERIDOSIDE APIGENIN-7-RHAMNOGLUCOSIDE RHOIFOLIN 7-[[2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-benzopyran-4-one RHOIFOLIN WITH HPLC apigenin 7-O-hesperidoside 2-(4-Hydroxyphenyl)-5-hydroxy-7-(2-O-α-L-rhamnopyranosyl-β-D-glucopyranosyloxy)-4H-1-benzopyran-4-one 2-(4-Hydroxyphenyl)-5-hydroxy-7-[2-O-(α-L-rhamnopyranosyl)-β-D-glucopyranosyloxy]-4H-1-benzopyran-4-one 7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one Rhoifoloside C12627 7-((2-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5- hydroxy-2-(4-hydroxyphenyl)-4H-benzopyran-4-one APIGENIN-7-NEOHESPERIDOSIDE hplc Rhoifolin, froM Turpinia Montana 4H-1-Benzopyran-4-one,7-[[2-O-(6-deoxy-L-mannopyranosyl)-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-hydroxyphenyl)- Apigenin 7-O-neohesperidoside Rhoifolin Rhoifolin, 98%, from Turpinia montana Rhoifolin, 98%, from Turpinia montana (Bl.) Kurz. 7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one 4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-hydroxyphenyl)- Rhoifolin (15 mg) 7-(((2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one Rhoifolin-RM Rhoifolin, 10 mM in DMSO Rhoifolin (Standard) APIGENIN 7-O-NEOHESPERIDOSIDE Apigenin-7-O-rhamnoglucoside 17306-46-6 Carbohydrates BioChemical Biochemicals and Reagents Disaccharide Inhibitors reagent Tri-substituted Flavones chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract
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