Indole-7-carboxaldehyde
- CAS No.
- 1074-88-0
- Chemical Name:
- Indole-7-carboxaldehyde
- Synonyms
- 1H-INDOLE-7-CARBALDEHYDE;1H-INDOLE-5-CARBALDEHYDE;e-7-carboxaL;7-FORMYLINDOLE;7-Indolealdehyde;INDOLE-7-ALDEHYDE;7-Formyl-1H-indole;RARECHEM AH BS 0111;INDOLE-7-CARBALDEHYDE;7-Indolecarboxaldehyde
- CBNumber:
- CB8731641
- Molecular Formula:
- C9H7NO
- Molecular Weight:
- 145.16
- MDL Number:
- MFCD01318152
- MOL File:
- 1074-88-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Indole-7-carboxaldehyde 97% | 632414 | 1g | $120 |
| Indole-7-carboxaldehyde 97% | 632414 | 5g | $303 |
| 1H-Indole-7-carbaldehyde min. 98.0 % | I0701 | 1G | $46 |
| 1H-Indole-7-carbaldehyde min. 98.0 % | I0701 | 5G | $139 |
| Indole-7-carboxaldehyde (7-Formylindole) | I0797-77E | 250mg | $347 |
| More product size | |||
| Melting point | 87-91 °C (lit.) |
|---|---|
| Boiling point | 339.1±15.0 °C(Predicted) |
| Density | 1.278±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform, Dichloromethane |
| pka | 15.50±0.30(Predicted) |
| form | Solid |
| color | Yellow Crystalline |
| Water Solubility | insoluble |
| Sensitive | Air Sensitive |
| BRN | 1524960 |
| InChI | InChI=1S/C9H7NO/c11-6-8-3-1-2-7-4-5-10-9(7)8/h1-6,10H |
| InChIKey | XQVZDADGTFJAFM-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=CC=C2C=O)C=C1 |
| CAS DataBase Reference | 1074-88-0(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H317 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-43 | |||||||||
| Safety Statements | 36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10 | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Skin Sens. 1 |
|||||||||
| NFPA 704 |
|
Indole-7-carboxaldehyde price More Price(82)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 632414 | Indole-7-carboxaldehyde 97% | 1074-88-0 | 1g | $120 | 2026-04-30 | Buy |
| Sigma-Aldrich | 632414 | Indole-7-carboxaldehyde 97% | 1074-88-0 | 5g | $303 | 2023-06-20 | Buy |
| TCI Chemical | I0701 | 1H-Indole-7-carbaldehyde min. 98.0 % | 1074-88-0 | 1G | $46 | 2026-04-30 | Buy |
| TCI Chemical | I0701 | 1H-Indole-7-carbaldehyde min. 98.0 % | 1074-88-0 | 5G | $139 | 2026-04-30 | Buy |
| Usbiological | I0797-77E | Indole-7-carboxaldehyde (7-Formylindole) | 250mg | $347 | 2026-06-03 | Buy |
Indole-7-carboxaldehyde Chemical Properties,Uses,Production
Chemical Properties
Yellow Crystalline Solid
Uses
Indole-7-carboxaldehyde (cas# 1074-88-0) is a compound useful in organic synthesis.
Uses
Indole-7-carboxaldehyde is used in an efficient synthesis of fused pyrroloquinolinedicarboxylates from acetylenedicarboxylates and triphenylphosphine. 1.reactant for preparation of antiandrogens. 2.reactant for preparation of antiplatelet agent. 3.reactant for preparation of liver
Definition
ChEBI: Indole-7-carboxaldehyde is a member of indoles.
Synthesis Reference(s)
Synthetic Communications, 36, p. 1051, 2006 DOI: 10.1080/00397910500503470
Synthesis
1074-87-9
1074-88-0
General procedure for the synthesis of indole-7-carboxaldehyde from (1H-indol-7-yl)methanol: (1H-indol-7-yl)methanol (8.0 g, 54.3 mmol) was dissolved in 400 mL of dichloromethane, and activated manganese(IV) oxide (85%, 41.0 g, 0.40 mol) was added. The reaction mixture was stirred at room temperature for 72 hours. Upon completion of the reaction, 200 mL of dichloromethane and 400 mL of methanol were added to the mixture, followed by filtration through a silica gel pad to remove solid impurities. The filtrate was concentrated to give the crude product, which was further purified by silica gel column chromatography to afford the target product 1H-indole-7-carboxaldehyde (I-1) (6.55 g, 83% yield). The structure of the product was confirmed by 1H-NMR (CDCl3).
References
[1] Synthetic Communications, 2006, vol. 36, # 8, p. 1051 - 1056
[2] Patent: US2006/79520, 2006, A1. Location in patent: Page/Page column 43
[3] Patent: WO2006/44415, 2006, A2. Location in patent: Page/Page column 78; 106-107
[4] Journal of the American Chemical Society, 2006, vol. 128, # 12, p. 4023 - 4034
[5] Chemical and Pharmaceutical Bulletin, 1986, vol. 34, # 10, p. 4116 - 4125
Indole-7-carboxaldehyde Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2165 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
View Lastest Price from Indole-7-carboxaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-04-04 | Indole-7-carboxaldehyde
1074-88-0
|
1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
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2020-06-02 | 7-Formylindole Indole-7-carboxaldehyde in stock Factory
1074-88-0
|
$1.00 | 1KG | TOP 3 Factory in China | Chemwill Asia Co.,Ltd. | ||
 |
2019-12-26 | Indole-7-carboxaldehyde
1074-88-0
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- Indole-7-carboxaldehyde
1074-88-0
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 7-Formylindole Indole-7-carboxaldehyde in stock Factory
1074-88-0
- $1.00
- TOP 3 Factory in China
- Chemwill Asia Co.,Ltd.
-
- Indole-7-carboxaldehyde
1074-88-0
- $1.00
- 99%
- Career Henan Chemical Co
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