5-METHOXY-PYRIDINE-3-CARBALDEHYDE
- CAS No.
- 113118-83-5
- Chemical Name:
- 5-METHOXY-PYRIDINE-3-CARBALDEHYDE
- Synonyms
- 5-METHOXYNICOTINALDEHYDE;3-FORMYL-5-METHOXYPYRIDINE;3-ForMyl-5-Methoxypyridin...;5-Methoxynicotinaldehyde 97%;5-Methoxypyridin-3-carbaldehyde;5-Methoxy-pyridinecarboxaldehyde;5-Methoxy-3-pyridinecarbaldehyde;5-methxoypyridine-3-carbaldehyde;5-METHOXY-PYRIDINE-3-CARBALDEHYDE;-Methoxy-3-pyridinecarboxaldehyde
- CBNumber:
- CB8764353
- Molecular Formula:
- C7H7NO2
- Molecular Weight:
- 137.14
- MDL Number:
- MFCD07437946
- MOL File:
- 113118-83-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Methoxynicotinaldehyde 97% | OR46113 | 1g | $21 |
| 5-Methoxynicotinaldehyde 97% | OR46113 | 5g | $43 |
| 5-Methoxynicotinaldehyde 97% | OR46113 | 10g | $81 |
| 5-Methoxynicotinaldehyde 97% | OR46113 | 25g | $196 |
| 5-Methoxy-3-pyridinecarboxaldehyde 97% | AS50395 | 1g | $28 |
| More product size | |||
| Melting point | 28-32 °C |
|---|---|
| Boiling point | 262.1±20.0 °C(Predicted) |
| Density | 1.159±0.06 g/cm3(Predicted) |
| Flash point | 100 °C |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | 2.52±0.10(Predicted) |
| Appearance | Colorless to light yellow <28°C Solid,>32°C Liquid |
| InChI | InChI=1S/C7H7NO2/c1-10-7-2-6(5-9)3-8-4-7/h2-5H,1H3 |
| InChIKey | YOVIXSRXKCZJRN-UHFFFAOYSA-N |
| SMILES | C1=NC=C(OC)C=C1C=O |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
5-METHOXY-PYRIDINE-3-CARBALDEHYDE price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR46113 | 5-Methoxynicotinaldehyde 97% | 113118-83-5 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR46113 | 5-Methoxynicotinaldehyde 97% | 113118-83-5 | 5g | $43 | 2026-06-04 | Buy |
| Apolloscientific | OR46113 | 5-Methoxynicotinaldehyde 97% | 113118-83-5 | 10g | $81 | 2026-06-04 | Buy |
| Apolloscientific | OR46113 | 5-Methoxynicotinaldehyde 97% | 113118-83-5 | 25g | $196 | 2026-06-04 | Buy |
| Activate Scientific | AS50395 | 5-Methoxy-3-pyridinecarboxaldehyde 97% | 113118-83-5 | 1g | $28 | 2026-06-04 | Buy |
5-METHOXY-PYRIDINE-3-CARBALDEHYDE Chemical Properties,Uses,Production
Uses
5-Methoxy-pyridine-3-carboxaldehyde is mainly used as an organic synthesis intermediate and can be used to synthesize various organic molecules containing a pyridine skeleton. Its highly reactive aldehyde group makes it an important starting material for synthesizing complex molecules.
Chemical Properties
White to yellow to orange to brown solid
Synthesis
50720-12-2
68-12-2
113118-83-5
3-Bromo-5-methoxypyridine (100 mg, 0.53 mmol) was placed in an oven-dried round-bottomed flask equipped with a magnetic stir bar and dissolved in anhydrous tetrahydrofuran (1 mL). Subsequently, isopropylmagnesium chloride (0.3 mL) was added at 0 °C and the resulting mixture was stirred at room temperature for 2 h (the solution turned light brown). Then, anhydrous tetrahydrofuran (0.1 mL) solution of N,N-dimethylformamide (0.1 mL) was slowly added. The initially formed solid gradually dissolved and the color of the solution changed from light brown to light yellow. after 1 h, the reaction mixture was cooled to 0 °C and the reaction was quenched with deionized water (2 mL). The organic layer was separated and the aqueous layer was further extracted with dichloromethane (3 x 3 mL). The organic layers were combined and dried over anhydrous sodium sulfate and subsequently concentrated in vacuum on a rotary evaporator. The crude product was purified by gradient silica gel column chromatography with the eluent being a solvent mixture of hexane and ethyl acetate (ratio from 20:1 to 1:1) to afford the target product 5-methoxy-pyridine-3-carbaldehyde as a colorless slurry (45 mg, 63% yield).1H NMR (500 MHz, CDCl3): δ 10.09 (s, 1H), 8.65 (d, J = 0.9 Hz, 1H), 8.54 (d, J = 3.1 Hz, 1H), 7.60 (dd, J = 5.1, 1.5 Hz, 1H).13C NMR (125 MHz, CDCl3): δ 190.6, 156.2, 145.1, 144.8, 132.0, 116.3, 55.7.
References
[1] Tetrahedron Letters, 2005, vol. 46, # 11, p. 1867 - 1871
[2] Tetrahedron, 2001, vol. 57, # 20, p. 4447 - 4454
[3] Biochemistry, 2010, vol. 49, # 49, p. 10421 - 10439
[4] Patent: US2014/309427, 2014, A1. Location in patent: Paragraph 0157; 0158
[5] Patent: WO2007/84560, 2007, A2. Location in patent: Page/Page column 164
5-METHOXY-PYRIDINE-3-CARBALDEHYDE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| Nanjing Fred Technology Co., Ltd. | +86-02584696168 15380713688 | Austin@fredchem.cn | CHINA | 865 | 58 |
View Lastest Price from 5-METHOXY-PYRIDINE-3-CARBALDEHYDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | 5-METHOXY-PYRIDINE-3-CARBALDEHYDE
113118-83-5
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2021-07-02 | 5-METHOXY-PYRIDINE-3-CARBALDEHYDE
113118-83-5
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-06 | 5-METHOXY-PYRIDINE-3-CARBALDEHYDE
113118-83-5
|
$1.00 | 1kg | 99% | Career Henan Chemical Co |
-
- 5-METHOXY-PYRIDINE-3-CARBALDEHYDE
113118-83-5
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 5-METHOXY-PYRIDINE-3-CARBALDEHYDE
113118-83-5
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 5-METHOXY-PYRIDINE-3-CARBALDEHYDE
113118-83-5
- $1.00
- 99%
- Career Henan Chemical Co
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