3-Amino-5-methylpyrazole
- CAS No.
- 31230-17-8
- Chemical Name:
- 3-Amino-5-methylpyrazole
- Synonyms
- 5-Methyl-1H-pyrazol-3-amine;3-METHYL-1H-PYRAZOL-5-AMINE;5-AMINO-3-METHYLPYRAZOLE;3-Methyl-5-aminopyrazole;3,1-AMP;3,5-AMP;AKOS B016021;3-Amino-5-methyL;BUTTPARK 48\04-98;AKOS BBS-00004647
- CBNumber:
- CB9174450
- Molecular Formula:
- C4H7N3
- Molecular Weight:
- 97.12
- MDL Number:
- MFCD00051640
- MOL File:
- 31230-17-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3-Methyl-1H-pyrazol-5-amine AldrichCPR | CDS004036 | 250 mg | $77.9 |
| 3-Amino-5-methylpyrazole 97% | 340200 | 25g | $52.6 |
| 3-Amino-5-methylpyrazole 97% | 340200 | 100g | $200 |
| 3-Amino-5-methylpyrazole >96.0%(GC) | A1133 | 25g | $151 |
| 5-Amino-3-methylpyrazole | A1379-02A | 5g | $312 |
| More product size | |||
| Melting point | 45-47 °C (lit.) |
|---|---|
| Boiling point | 213 °C/14 mmHg (lit.) |
| Density | 1.0548 (rough estimate) |
| refractive index | 1.5200 (estimate) |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Soluble in Dichloromethane and Methanol. |
| form | Solid |
| pka | 15.84±0.10(Predicted) |
| color | Light yellow to orange |
| Sensitive | Air Sensitive |
| BRN | 1904 |
| Stability | Light Sensitive |
| InChI | 1S/C4H7N3/c1-3-2-4(5)7-6-3/h2H,1H3,(H3,5,6,7) |
| InChIKey | FYTLHYRDGXRYEY-UHFFFAOYSA-N |
| SMILES | Cc1cc(N)n[nH]1 |
| CAS DataBase Reference | 31230-17-8(CAS DataBase Reference) |
| FDA UNII | 7M23CZ0CSD |
| EPA Substance Registry System | 1H-Pyrazol-3-amine, 5-methyl- (31230-17-8) |
| UNSPSC Code | 12352116 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-22 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29331990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
3-Amino-5-methylpyrazole price More Price(103)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS004036 | 3-Methyl-1H-pyrazol-5-amine AldrichCPR | 31230-17-8 | 250 mg | $77.9 | 2026-04-30 | Buy |
| Sigma-Aldrich | 340200 | 3-Amino-5-methylpyrazole 97% | 31230-17-8 | 25g | $52.6 | 2023-06-20 | Buy |
| Sigma-Aldrich | 340200 | 3-Amino-5-methylpyrazole 97% | 31230-17-8 | 100g | $200 | 2023-06-20 | Buy |
| TCI Chemical | A1133 | 3-Amino-5-methylpyrazole >96.0%(GC) | 31230-17-8 | 25g | $151 | 2026-04-30 | Buy |
| Usbiological | A1379-02A | 5-Amino-3-methylpyrazole | 31230-17-8 | 5g | $312 | 2026-06-03 | Buy |
3-Amino-5-methylpyrazole Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powde
Uses
3-Amino-5-methylpyrazole was employed as beta-sheet template to investigate its interaction with ferrocenoyl-dipeptides. It was also used in the synthesis of 4-aryl-3,7,7-trimethyl-2,4,6,7,8,9-hexahydropyrazolo[3,4-b]quinolin-5-ones.
Uses
3-Amino-5-methyl-1H-pyrazole was employed as beta-sheet template to investigate its interaction with ferrocenoyl-dipeptides. It is also used in the synthesis of 4-aryl-3,7,7-trimethyl-2,4,6,7,8,9-hexahydropyrazolo[3,4-b]quinolin-5-ones. It can react with 4-Ethoxymethylene-2-phenyl-4H-oxazol-5-one to get N-(2-Methyl-7-oxo-4,7-dihydro-pyrazolo[1,5-a]pyrimidin-6-yl)-benzamide.
Definition
ChEBI: 5-Methyl-3-pyrazolamine is a heterocyclic compound and a dicarboximide.
General Description
Complexation of the amino- and carboxyl-protected tripeptide with 3-amino-5-methylpyrazole was studied by low-temperature NMR experiments in a freonic solvent.
Synthesis
1118-61-2
31230-17-8
General procedure for the synthesis of 3-amino-5-methyl-1H-pyrazole from 3-aminobut-2-enenenitrile: 10 g of 3-aminobut-2-enenitrile and 5 L of ethanol were added to a 10 L reaction flask and stirred until completely dissolved. Subsequently, 2500 g of 80% hydrazine hydrate was added. After stirring at room temperature for 10-20 minutes, the reaction was slowly heated to reflux, keeping the reaction temperature between 85-95 °C. Note: A large amount of gas is generated during the reaction. When the reaction has been carried out for 1.5-2.5 hours, confirm the complete reaction of the feedstock by TLC monitoring. Upon completion of the reaction, the reaction solution is concentrated under reduced pressure at 50-60°C to 20-30% of the original volume. Finally, a light yellow liquid (converted to a light yellow solid after cooling) was obtained by oil pump distillation in a yield of 2230 g with 94.2% yield. The purity of 3-amino-5-methyl-1H-pyrazole was higher than 98% and the content of single impurity was lower than 0.5% by GC and HPLC analysis.
References
[1] Patent: CN108341782, 2018, A. Location in patent: Paragraph 0018; 0019; 0021; 0022
[2] Patent: CN104844567, 2017, B. Location in patent: Paragraph 0031; 0034; 0039; 0044
3-Amino-5-methylpyrazole Preparation Products And Raw materials
Raw materials
1of5
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
View Lastest Price from 3-Amino-5-methylpyrazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-08 | 3-Amino-5-methylpyrazole
31230-17-8
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-06-04 | 3-Amino-5-methylpyrazole
31230-17-8
|
1kg | 98% | 20TON | Hubei Lidu New Material Technology Co., Ltd | ||
 |
2025-11-18 | 3-Amino-5-methylpyrazole
31230-17-8
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- 3-Amino-5-methylpyrazole
31230-17-8
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 3-Amino-5-methylpyrazole
31230-17-8
- $0.00
- 98%
- Hubei Lidu New Material Technology Co., Ltd
-
- 3-Amino-5-methylpyrazole
31230-17-8
- $1.10
- 99.00%
- Dideu Industries Group Limited
