Pranoprofen
- CAS No.
- 52549-17-4
- Chemical Name:
- Pranoprofen
- Synonyms
- 2-(5H-Chromeno[2,3-b]pyridin-7-yl)propanoic acid;Niflan;Y 8004;Cesflan;Oftalar;Pralofen;Praprofen;ranoprofen;PRANOPROFEN;pyranoprofen
- CBNumber:
- CB9189564
- Molecular Formula:
- C15H13NO3
- Molecular Weight:
- 255.27
- MDL Number:
- MFCD00866111
- MOL File:
- 52549-17-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Pranoprofen ≥98% (HPLC) | SML1423 | 50mg | $42.9 |
| Pranoprofen ≥98% (HPLC) | SML1423 | 250mg | $126 |
| Pranoprofen min. 98.0 % | P2778 | 1G | $197 |
| Pranoprofen min. 98.0 % | P2778 | 5G | $588 |
| Pranoprofen-13C-d3 ≥99%deuteratedforms(d1-d3) | 34009 | 500μg | $124 |
| More product size | |||
| Melting point | 182-183° |
|---|---|
| Boiling point | 398.5°C (rough estimate) |
| Density | 1.1654 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 4.27±0.10(Predicted) |
| form | powder |
| color | white to beige |
| InChI | InChI=1S/C15H13NO3/c1-9(15(17)18)10-4-5-13-12(7-10)8-11-3-2-6-16-14(11)19-13/h2-7,9H,8H2,1H3,(H,17,18) |
| InChIKey | TVQZAMVBTVNYLA-UHFFFAOYSA-N |
| SMILES | C(C1C=CC2OC3=NC=CC=C3CC=2C=1)(C)C(=O)O |
| CAS DataBase Reference | 52549-17-4(CAS DataBase Reference) |
| FDA UNII | 2R7O1ET613 |
| ATC code | S01BC09 |
| UNSPSC Code | 41106500 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P301+P310+P330 | |||||||||
| RIDADR | UN 2811 6.1 / PGIII | |||||||||
| WGK Germany | WGK 1 | |||||||||
| RTECS | DJ3100950 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral | |||||||||
| Toxicity | LD50 in male mice, rats (mg/kg): 447.3, 87.3 orally (Edanaga) | |||||||||
| NFPA 704 |
|
Pranoprofen price More Price(90)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1423 | Pranoprofen ≥98% (HPLC) | 52549-17-4 | 50mg | $42.9 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML1423 | Pranoprofen ≥98% (HPLC) | 52549-17-4 | 250mg | $126 | 2026-04-30 | Buy |
| TCI Chemical | P2778 | Pranoprofen min. 98.0 % | 52549-17-4 | 1G | $197 | 2026-04-30 | Buy |
| TCI Chemical | P2778 | Pranoprofen min. 98.0 % | 52549-17-4 | 5G | $588 | 2026-04-30 | Buy |
| Cayman Chemical | 34009 | Pranoprofen-13C-d3 ≥99%deuteratedforms(d1-d3) | 500μg | $124 | 2026-04-30 | Buy |
Pranoprofen Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Originator
Niflan, Yoshitomi ,Japan ,1981
Uses
Pranoprofen is an anti-inflammatory used in ophthalmology.
Definition
ChEBI: Pranoprofen is a pyridochromene.
Manufacturing Process
A mixture of 100 g of ethyl 2-cyano-2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionate, 500 ml of glacial acetic acid and 200 g of concentrated hydrochloric acid is refluxed for 48 hours. The reaction mixture is concentrated, and the residue is dissolved in hot water. The solution is adjusted to pH 2 to 3 by addition of 10% sodium hydroxide. The resulting crystalline precipitate is washed thoroughly with water, and recrystallized from aqueous dioxane to give 74 g of 2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionic acid as white crystals melting at 183°C to 183.5°C.
Therapeutic Function
Analgesic, Antiinflammatory
General Description
Pranoprofen is an arylalkanoic acid and a non-steroidal anti-inflammatory drug.
Biochem/physiol Actions
Pranoprofen is used in eyes to treat chronic allergic conjunctivitis. It is also used as an anti-inflammatory and analgesic drug after strabismus surgery.
Pranoprofen Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-18192627656 | 1059@dideu.com | China | 3587 | 58 |
| airuikechemical co., ltd. | +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Hebei shuoxi biotechnology co. LTD | +8613081092107 | CHINA | 964 | 58 | |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Nanjing Shizhou Biotechnology Co., Ltd | +86-15850508050 | sean.lv@synzest.com | China | 323 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
View Lastest Price from Pranoprofen manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-28 | Pranoprofen
52549-17-4
|
$1.90 | 1KG | 99% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-04-22 | Pranoprofen
52549-17-4
|
$30.00-68.00 | 99.88% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-04-22 | Pranoprofen
52549-17-4
|
$30.00-68.00 | 99.88% | 10g | TargetMol Chemicals Inc. |
-
- Pranoprofen
52549-17-4
- $1.90
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- Pranoprofen
52549-17-4
- $30.00-68.00
- 99.88%
- TargetMol Chemicals Inc.
-
- Pranoprofen
52549-17-4
- $30.00-68.00
- 99.88%
- TargetMol Chemicals Inc.
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