一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

ChemicalBook >> CAS DataBase List >>CASTANOSPERMINE

CASTANOSPERMINE

CAS No.
79831-76-8
Chemical Name:
CASTANOSPERMINE
Synonyms
CastanosperMin;CASTANOSPERMINE;(+)-Castanospermine;Castanospermine ,98%;Castanospermine, 10 mM in DMSO;1,6,7,8-TETRAHYDROXYOCTAHYDROINDOLIZINE;CASTANOSPERMINE, CASTANOSPERMUM AUSTRALE;(1S,6S,7R,8R,8AR)-1,6,7,8-TETRAHYDROXY-&;Castanospermine from Castanospermum austral;(8aα)-Octahydroindolizine-1β,6α,7β,8α-tetrol
CBNumber:
CB9387977
Molecular Formula:
C8H15NO4
Molecular Weight:
189.21
MDL Number:
MFCD00017555
MOL File:
79831-76-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-03 11:24:09
Product description Number Pack Size Price
(1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine 98% 532673 100mg $252
Castanospermine 218775 1mg $78.3
Castanospermine ≥98% 11313 5mg $48
Castanospermine ≥98% 11313 10mg $80
Castanospermine ≥98% 11313 25mg $160
More product size

CASTANOSPERMINE Properties

Melting point 213-217 °C (lit.)
alpha D25 +79.7° (c = 0.93 in water)
Boiling point 421.9±45.0 °C(Predicted)
Density 1.53±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility 1 M HCl: 20 mg/mL, clear, very faintly yellow
form White solid
pka 6.09(at 25℃)
color White or off-white
optical activity [α]20/D +80°, c = 0.9 in H2O
Water Solubility Soluble in water
Merck 13,1906
BRN 3588654
Stability Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
InChI 1S/C8H15NO4/c10-4-1-2-9-3-5(11)7(12)8(13)6(4)9/h4-8,10-13H,1-3H2/t4-,5-,6+,7+,8+/m0/s1
InChIKey JDVVGAQPNNXQDW-TVNFTVLESA-N
SMILES [H][C@]12[C@@H](O)CCN1C[C@H](O)[C@@H](O)[C@@H]2O
CAS DataBase Reference 79831-76-8(CAS DataBase Reference)
FDA UNII Q0I3184XM7
UNSPSC Code 12352204
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P261-P280h-P301+P312a-P304+P340-P321-P501a
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36
WGK Germany  3
F  10-21
HS Code  2921290090
Storage Class 11 - Combustible Solids
NFPA 704
0
3 0

CASTANOSPERMINE price More Price(82)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 532673 (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine 98% 79831-76-8 100mg $252 2026-04-30 Buy
Sigma-Aldrich 218775 Castanospermine 79831-76-8 1mg $78.3 2026-04-30 Buy
Cayman Chemical 11313 Castanospermine ≥98% 79831-76-8 5mg $48 2026-04-30 Buy
Cayman Chemical 11313 Castanospermine ≥98% 79831-76-8 10mg $80 2026-04-30 Buy
Cayman Chemical 11313 Castanospermine ≥98% 79831-76-8 25mg $160 2026-04-30 Buy
Product number Packaging Price Buy
532673 100mg $252 Buy
218775 1mg $78.3 Buy
11313 5mg $48 Buy
11313 10mg $80 Buy
11313 25mg $160 Buy

CASTANOSPERMINE Chemical Properties,Uses,Production

Description

Glucosidases catalyze the cleavage of individual glucosyl residues from various glycoconjugates, including complex carbohydrates and glycoproteins. Castanospermine is an inhibitor of both α- and β-glucosidases, inhibiting lysosomal and neutral α-glucosidases with Ki values of 0.1 and 10 μM, respectively, and lysosomal and cytosolic β-glucosidases with Ki values of 7 and 40 μM, respectively. It is effective both in vitro and in vivo. Through its effects on glucosidases, castanospermine blocks N-linked glycosylation during post-translational modification of proteins, affecting protein trafficking and cell functions that are dependent on glycosylation, including angiogenesis. Castanospermine also interferes with viral replication and infection that is dependent on glucosidase activity.

Chemical Properties

White Crystalline Solid

Occurrence

The seeds of Castanospermum australe yield this simple alkaloid. It forms colourless crystals from EtOH and is dextrorotatory with a specific rotation of [α]D25 +79.7° (c 0.93, H20). Castano spermine has been characterized as the crystalline methiodide, m.p. 11O-112°C.

Uses

Castanospermine, is used as a glycosidase inhibitor and antiinflammatory agent.castanospermine is used to inhibit syncytium formation between HIV-infected and CD4-expressing cells and may also interfere with infectivity. It has also been demonstrated that this agent inhibits inflammation at the level of leukocyte extravasation in rat models of experimental adjuvant-induced arthritis and autoimmune encephalomyelitis. Castanospermine is an inhibitor of Glucosidase I, Maltase-glucoamylase, and MANBA. Potent inhibitor of α- and β-glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids). Inhibits HIV syncytium formation and replication.

Uses

a-L-fucosidases inhibitor

Uses

Castanospermine is a plant alkaloid shown to be a potent inhibitor of lysosomal a-or beta- glucosidase. It also inhibits mammalian glucosidase 1 and beta-mannosidase from sweet almonds and fungal beta-xylosidase.

Definition

ChEBI: Castanospermine is a tetrahydroxyindolizidine alkaloid that consists of octahydroindolizine having four hydroxy substituents located at positions 1, 6, 7 and 8 (the 1S,6S,7R,8R,8aR-diastereomer). It has a role as a metabolite, an anti-HIV-1 agent, an anti-inflammatory agent and an EC 3.2.1.* (glycosidase) inhibitor.

Biological Activity

Potent inhibitor of α - and β -glucosidases, especially glucosidase l (required for glucoprotein processing by transfer of mannose and glucose from asparagine-linked lipids). Inhibits HIV syncytium formation and replication.

storage

Store at RT

References

[1] RICK SAUL  A. D E  R J Molyneux. Studies on the mechanism of castanospermine inhibition of α- and β-glucosidases[J]. Archives of biochemistry and biophysics, 1984, 230 2: Pages 668-675. DOI:10.1016/0003-9861(84)90448-x
[2] REINALD REPPS. The effects of processing inhibitors of N-linked oligosaccharides on the intracellular migration of glycoprotein E2 of mouse hepatitis virus and the maturation of coronavirus particles.[J]. The Journal of Biological Chemistry, 1985, 61 1: 15873-15879. DOI:10.1016/s0021-9258(17)36339-1
[3] ROB A. GRUTERS. Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase[J]. Nature, 1987, 330 6143: 74-77. DOI:10.1038/330074a0
[4] J L FRANC  J L  A Giraud. Effects of deoxymannojirimycin and castanospermine on the polarized secretion of thyroglobulin.[J]. Endocrinology, 1990, 126 3: 1464-1470. DOI:10.1210/endo-126-3-1464
[5] R PILI. The alpha-glucosidase I inhibitor castanospermine alters endothelial cell glycosylation, prevents angiogenesis, and inhibits tumor growth.[J]. Cancer research, 1995, 55 13: 2920-2926.
[6] B.L. RHINEHART . Castanospermine blocks the hyperglycemic response to carbohydrates in vivo: A result of intestinal disaccharidase inhibition[J]. Life sciences, 1987, 41 20: Pages 2325-2331. DOI:10.1016/0024-3205(87)90546-7

Global( 137)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3619 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39039 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+86-18621343501; +undefined18621343501 product@acmec-e.com China 33324 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Suzhou ARTK Medchem Co., Ltd. 		+8618118463618 sales1@artkmedchem.com China 39021 58
SHANGHAI KEAN TECHNOLOGY CO., LTD. 		+8613817748580 cooperation@kean-chem.com China 40066 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739 info@dycnchem.com China 53803 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39927 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58

View Lastest Price from CASTANOSPERMINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Castanospermine pictures 2026-06-02 Castanospermine
79831-76-8
 $32.00-52.00 99.93% 10g TargetMol Chemicals Inc.
(1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine pictures 2021-07-02 (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine
79831-76-8
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
1,6,7,8-indolizinetetrol,octahydro-,(1s-(1-alpha,6-beta,7-alpha,8-beta,8a-bet 7,8-indolizinetetrol,octahydro-,(1s,6s,7r,8r,8ar)-6 octahydro-1,6,7,8-indolizinetetrol(1s-(1-alpha,6-beta,7-alpha,8-beta,8a-beta CASTANOSPERMINE CASTANOSPERMINE, CASTANOSPERMUM AUSTRALE [1S-(1A,6B,7A,8B,8A-BETA)]-OCTAHYDRO-1,6,7,8-INDOLIZINETETROL (1S,6S,7R,8AR)-TETRAHYDROXYOCTAHYDROINDOLIZINE (1S,6S,7R,8R,8AR)-1,6,7,8-TETRAHYDROXYINDOLIZIDINE (1S,6S,7R,8R,8AR)-1,6,7,8-TETRAHYDROXYOCTAHYDROINDOLIZINE (1S,6S,7R,8R,8AR)-OCTAHYDRO-1,6,7,8-INDOLIZINETETROL 1,6,7,8-TETRAHYDROXYOCTAHYDROINDOLIZINE (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizidine, (1S,6S,7R,8R,8aR)-Octahydro-1,6,7,8-indolizinetetrol 1,6,7,8-Tetrahydroxyoctahydroindolizine, Castanospermine, (1S,6S,7R,8R,8aR)-Octahydro-1,6,7,8-indolizinetetrol, (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizidine Castanospermine from Castanospermum austral Castanospermine Castanospermum australe seeds castanospermine from castanospermum australe seeds castanospermine from castanospermum*australe seed (1S,6S,7R,8R,8AR)-1,6,7,8-TETRAHYDROXY-& 1,6,7,8-Indolizinetetrol, octahydro-, (1S,6S,7R,8R,8aR)- (1s,6s,7r,8r,8ar)-1,6,7,8-tetrahydroxyoctahydroindolizidine [1S-(1alpha,6beta,7alpha,8beta,8alphabeta)]-Octahydro-1,6,7,8-indolizinetetrol (3S,4R,5R,6R,7S)-1-Azabicyclo[4.3.0]nonane-3,4,5,7-tetrol (8aα)-Octahydroindolizine-1β,6α,7β,8α-tetrol [1S-(1α,6β,7α,8β,8aβ)]-Octahydro-1,6,7,8-indolizinetetrol Castanospermine ,98% CastanosperMin (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine 98% Castanospermine/ (1S,6S,7R,8R,8Ar)-Indolizidine-1,6,7,8-Tetrol /(1S,6S,7R,8R,8aR)-1,2,3,5,6,7,8,8a-Octahydroindolizine-1,6,7,8-Tetrol (1S,6S,7R,8R,8aR)-2,3,4,5,6,7,8,8a-octahydro-1H-indolizin-4-ium-1,6,7,8-tetrol Castanospermine, Castanospermum australe - CAS 79831-76-8 - Calbiochem (1S,6S,7R,8R,8aR)-octahydroindolizine-1,6,7,8-tetrol (1S,6S,7R,8R,8aR)-Octahydroindolizine-1,6,7,8-tetraol Castanospermine,inhibit,Inhibitor,Glucosidase (+)-Castanospermine Castanospermine, alpha- and beta-glucosidase activity inhibitor Castanospermine, 10 mM in DMSO Castanospermine, Castanospermum australe (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine 79831-76-8 Enzyme Inhibitors Enzyme Inhibitors by Enzyme Glucosidase, alpha- Heterocyclic Building Blocks Indoles Substrate Analogs Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Type D to K BioChemical Biochemicals and Reagents Asymmetric Synthesis Chiral Building Blocks inhibitor Alkaloids All Inhibitors Glycosidase Inhibitors Inhibitors Miscellaneous Enzyme
花垣县| 壶关县| 镇雄县| 北碚区| 开化县| 株洲市| 潜山县| 克什克腾旗| 疏勒县| 弥勒县| 宁化县| 正宁县| 平塘县| 诸暨市| 土默特左旗| 华池县| 大庆市| 九寨沟县| 丰顺县| 栾城县| 虞城县| 廊坊市| 大埔县| 涞源县| 鄂伦春自治旗| 剑川县| 湟源县| 阳江市| 泾川县| 乌兰察布市| 保德县| 江川县| 正宁县| 玛多县| 特克斯县| 宝山区| 武穴市| 石首市| 宁乡县| 英山县| 壶关县|