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ChemicalBook >> CAS DataBase List >>Bromocresol green

Bromocresol green

CAS No.
76-60-8
Chemical Name:
Bromocresol green
Synonyms
Green;BCG;BROMCRESOL GREEN;BROMOCRESOL BLUE;BROMOCRESOL GREEN INDICATOR;BROMOCRESOL GREEN SULTONE FORM;BACILLUS OF CALMETTE AND GUERIN;γ-Sultone;vertdebromocresol;tetrabromo-m-cresolphthaleinsulfone
CBNumber:
CB9447060
Molecular Formula:
C21H14Br4O5S
Molecular Weight:
698.01
MDL Number:
MFCD00005874
MOL File:
76-60-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-30 15:36:39
Product description Number Pack Size Price
Bromocresol Green Sultone Form for microscopy (Bot., Hist., Vit.), indicator (pH 3.8-5.4) 17470 5G $66.8
Bromocresol Green Sultone Form for microscopy (Bot., Hist., Vit.), indicator (pH 3.8-5.4) 17470 25g $254
Bromocresol Green ACS reagent, Dye content 95% 114359 5g $59.7
Bromocresol Green ACS reagent, Dye content 95% 114359 25g $228
Bromocresol green indicator ACS,Reag. Ph Eur 1.08121 1g $230
More product size

Bromocresol green Properties

Melting point 225 °C (dec.) (lit.)
Density 0.79 g/mL at 20 °C
bulk density 350kg/m3
Flash point 12 °C
storage temp. no restrictions.
solubility Solubility Sparingly soluble in water; soluble in ethanol, ether, ethyl acetate
form Powder/Solid
pka 4.7(at 25℃)
Boiling point 626.0±55.0 °C(Predicted)
color Pale orange
PH Range 3.8(YELLOW)-5.4(BLUE)
PH 3.8~5.4
Water Solubility slightly soluble
λmax 423nm, 444nm, 617nm
Merck 14,1386
BRN 372527
Henry's Law Constant 1.5×1013 mol/(m3Pa) at 25℃, Zhang et al. (2010)
Stability Stable. Incompatible with strong oxidizing agents.
Major Application Sol-gel matrix, fuel cells, sensors, display device, inks, paints, one-steptester for ammonia, cosmet-tester for ammonia, packaging system, textiles, cleansing products, detergents, cosmetics, diapers, identifying fresh and stale rice, monitoring fish spoilage, detecting carbohydrates, lacting acid bacteria, treating neoplasms, cancer, vaginal infection test method, drugs, dental materials
Cosmetics Ingredients Functions COLORANT
InChI 1S/C21H14Br4O5S/c1-9-12(7-14(22)19(26)17(9)24)21(13-8-15(23)20(27)18(25)10(13)2)11-5-3-4-6-16(11)31(28,29)30-21/h3-8,26-27H,1-2H3
InChIKey FRPHFZCDPYBUAU-UHFFFAOYSA-N
SMILES Cc1c(Br)c(O)c(Br)cc1C2(OS(=O)(=O)c3ccccc23)c4cc(Br)c(O)c(Br)c4C
LogP 7.800 (est)
CAS DataBase Reference 76-60-8(CAS DataBase Reference)
NCI Dictionary of Cancer Terms BCG
FDA UNII 8YGN0Y942M
EPA Substance Registry System Bromcresol green (76-60-8)
UNSPSC Code 41116100
NACRES NB.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS02,GHS07,GHS08
Signal word  Danger
Hazard statements  H319-H360-H372-H373-H340-H350-H335-H336-H225
Precautionary statements  P501-P270-P202-P240-P260-P210-P233-P201-P243-P241-P242-P271-P264-P280-P370+P378-P308+P313-P337+P313-P305+P351+P338-P303+P361+P353-P304+P340+P312-P403+P233-P403+P235-P405
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  F,Xi,Xn
Risk Statements  11-36-67-36/37/38-20/21/22
Safety Statements  7-16-24/25-26-37/39-36
RIDADR  UN 1219 3/PG 2
WGK Germany  3
RTECS  SJ7456000
Autoignition Temperature 399 °C
TSCA  TSCA listed
HazardClass  3
PackingGroup  II
HS Code  29349990
Storage Class 11 - Combustible Solids
NFPA 704
1
1 0

Bromocresol green price More Price(99)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 17470 Bromocresol Green Sultone Form for microscopy (Bot., Hist., Vit.), indicator (pH 3.8-5.4) 76-60-8 5G $66.8 2026-04-30 Buy
Sigma-Aldrich 17470 Bromocresol Green Sultone Form for microscopy (Bot., Hist., Vit.), indicator (pH 3.8-5.4) 76-60-8 25g $254 2026-04-30 Buy
Sigma-Aldrich 114359 Bromocresol Green ACS reagent, Dye content 95% 76-60-8 5g $59.7 2026-04-30 Buy
Sigma-Aldrich 114359 Bromocresol Green ACS reagent, Dye content 95% 76-60-8 25g $228 2026-04-30 Buy
Sigma-Aldrich 1.08121 Bromocresol green indicator ACS,Reag. Ph Eur 76-60-8 1g $230 2026-04-30 Buy
Product number Packaging Price Buy
17470 5G $66.8 Buy
17470 25g $254 Buy
114359 5g $59.7 Buy
114359 25g $228 Buy
1.08121 1g $230 Buy

Bromocresol green Chemical Properties,Uses,Production

Chemical Properties

tan to yellow crystals

Uses

Bromocresol Green (BCG) is a pH sensitive triphenylmethane dye useful in a variety of colorimetric detection technologies. BCG is used as a tracking dye for DNA agarose gel electrophoresis, in protein determinations and in charge-transfer complexation processes. In TLC BCG is used for visualisation of the compounds with functional groups whose pKa is below 5.0.

Uses

Bromocresol Green is a pH sensitive indicator used in the growth medium for microorganisms and titrations. It is useful in various colorimetric detection studies and as an actively tracking dye for DNA agarose gel electrophoresis. It acts as an inhibitor of prostaglandin E2 transport protein. It is also used in TLC for visualizing compounds containing functional groups having pKa less than 5.

Uses

As indicator, pH 3.8 yellow; pH 5.4 blue-green.

Definition

ChEBI: Bromocresolgreen is a member of benzofurans.

Hazard

Moderately toxic.

Synthesis

A method of preparing bromocresol green in the following steps:

(1) 1.5 kg of bromine is dissolved in 1.25 liters of glacial acetic acid solution to obtain a bromine-glacial acetic acid mixture;

(2) 2 kg of pure m-cresol violet is dissolved in a solution of 2.5 liters of glacial acetic acid;

(3) The bromine-ice acetic acid mixture obtained in step (1) is slowly dripped into the solution in step (2) at a temperature not exceeding 80 C. After addition, stirring is continued and kept at 80 to 90 C. for 24 hours, and then filtered after cooling down, and the precipitate is washed twice with ice acetic acid, dried or pumped, and dried at 50 to 60 C. to obtain the crude bromocresol green. Moreover, the crude bromocresol green was recrystallized with benzene or glacial acetic acid to obtain pure bromocresol green, which crystallized into white, melting point 218-9C.

Purification Methods

Crystallise the dye from glacial acetic acid or dissolve it in aqueous 5% NaHCO3 solution and precipitate it from the hot solution by dropwise addition of aqueous HCl. Repeat this until the UV/VIS-extinction did not increase 423nm. It is an indicator: at pH 3.81 at max (yellow) and pH 5.4 (blue-green). [Beilstein 19/3 V 460.]

Bromocresol green Preparation Products And Raw materials

Global( 627)Suppliers
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Jiangsu Boquan Biotechnology Co., Ltd.
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Related Qustion

Ask a question
Q:What is the concentration of bromocresol green indicating solution?Theon - Jun 30,2026
A:When preparing bromocresol green solution, add 0.1 g in 100 mL Ethanol (20%) or 0.04 g in 0.58 mL Sodium Hydroxide solution, dilute 0.1 mol/L and fill up to 100 mL with water. It acts as pH indicator. Between pH 3.8-5.4, its color transitions gradually from yellow in acidic conditions to blue in basic conditions, passing through an intermediate green.

View Lastest Price from Bromocresol green manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Bromocresol green pictures 2026-07-25 Bromocresol green
76-60-8
0.99 RongNa Biotechnology Co.,Ltd
Bromocresol green pictures 2026-07-24 Bromocresol green
76-60-8
$666.00-999.00 1kg 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Bromocresol green pictures 2026-07-24 Bromocresol green
76-60-8
1KG 99% 1000kg WUHAN FORTUNA CHEMICAL CO., LTD
BROMOCRESOL GREEN ETHANOL (50) 3',3'',5',5''-TETRABROMO-3-CRESOLSULFONEPHTHALEIN 3',3'',5',5''-TETRABROMO-M-CRESOLSULFONEPHTHALEIN 3',3'',5',5''-TETRABROMO-M-CRESOLSULFONPHTHALEIN 3',3',5',5'-TETRABROMO-M-CRESOLSULFONPHTHALEIN 3,3',5,5'-TETRABROMO-M-CRESOLSULFONPHTHALEIN ALPHA,ALPHA-BIS(3,5-DIBROMO-4-HYDROXY-O-TOLYL)-ALPHA-HYDROXY-O-TOLUENESULFONIC ACID TETRABROMOCRESOLSULFONEPHTHALEIN MYCOBACTERIUM BOVIS 4,4’-(3h-2,1-benzoxathiol-3-ylidene)bis(2,6-dibromo-3-methylphenol)s,s-dioxide 4,4’-(3h-2,1-benzoxathiol-3-ylidene)bis(2,6-dibromo-m-cresol)s,s-dioxide m-cresol,4,4’-(3h-2,1-benzoxathiol-3-ylidene)bis(2,6-dibromo-,s,s-dioxide phenol,4,4’-(3h-2,1-benzoxathiol-3-ylidene)bis(2,6-dibromo-3-methyl-,s,s-diox BCG, Mycobacterium bovis bromcresol green crystalline bromcresol green spray bromocresol green for microscopy and complexometry 2,6-Dibromo-4-[3-(3,5-dibromo-4-hydroxy-2-methylphenyl)-1,1-dioxobenzo[c]oxathiol-3-yl]-3-methylphenol Bromocresol Greenozone friendly ready to use spray for TLCpure 3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-2,1-benzoxathiol 1,l-dioxide Bromocresol Green,pure,indicator grade Bromocresol Green,pure,ozone friendly ready to use spray for TLC Bromocresol Green,pure,conforms to ACS Bromocresol green, solution 0,04%, indicator Bromocresol green 1g [76-60-8] BROMOCRESOL GREEN, ACS Bromocresol Green p.a. Bromocresol Green,Free Acid 3,3′,5,5′-TetrabroMo-M-cresol sulfonaphthalein Methyl Red Mixed indicator powder BroMocresol Green, conforMs to ACS, pure 10GR BroMocresol Green, conforMs to ACS, pure 1GR BroMocresol Green, conforMs to ACS, pure 5GR BroMocresol Green, indicator grade, pure 25GR BroMocresol Green, indicator grade, pure 5GR BROMOCRESOL GREEN INDICATOR PH 3,8 - 5,4 3,3-Bis(3,5-dibromo-4-hydroxy-2-methylphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide 4,4'-(1,1-Dioxido-3H-2,1-benzoxathiole-3,3-diyl)bis(2,6-dibromo-3-methylphenol), 3',3'',5',5''-Tetrabromo-m-cresolsulphonephthalein BroMocresol green SynonyM: 3',3'',5',5''-TetrabroMo-M-cresolsulfonephthalein Bromocresol Green, conforms to ACS, pure Bromocresol Green, indicator grade, pure Phenol, 4,4-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis2,6-dibromo-3-methyl- BROMOCRESOLGREEN,REAGENT,ACS Bromocresol green Bromocresol Green (0.04% in ca. 50% Ethanol) [for Titration] Bromocresol Green (0.04% in Water) [for pH Determination] Bromocresol Green (contains NaOH) Ethanol Solution [for TLC Stain] Bromocresol Green, pH 3.8-5.4 (Yellow-Blue) Bromocresol Blue, 3μ,3μμ,5μ,5μμ-Tetrabromo-m-cresolsulfonephthalein Bromocresol Green, Reagent Bromocresol Green (contains NaOH) Ethanol Solution BROMOCRESOL GREEN 0.04 % (ETHANOL) tetrabromo-m-cresolsulphonephthalein BROMOCRESOL GREEN INDICATOR, REAG. PH. E UR. BROMCRESOL GREEN ACS REAGENT BROMOCRESOL GREEN SOLUTION, READY-TO-USE BROMOCRESOL GREEN A.C.S. REAGENT BromocresolGreenIndicatorGr-(BromocresolBlue)
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