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4'-(Trifluoromethyl)acetophenone

4'-(Trifluoromethyl)acetophenone structure

CAS No.: 709-63-7

Chemical Name:: 4'-(Trifluoromethyl)acetophenone

Synonyms: 4-(TRIFLUOROMETHYL)ACETOPHENONE;1-(4-Trifluoromethyl-phenyl)-ethanone;NSC 88346;4-Acetylbe;4-ACETYLBENZOFLUORIDE;On the trifluoroMethyl;4-ACETYLBENZOTRIFLUORIDE;P-TRIFLUOROMETHYLACETOPHENONE;4-(trifluromethyl)acetophenone;4-TRIFLUOROMETHYL BENZYLDEHYDE

CBNumber:: CB9717518

Molecular Formula:: C9H7F3O

Molecular Weight:: 188.15

MDL Number:: MFCD00000401

MOL File:: 709-63-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:51:36

Product description	Number	Pack Size	Price
4′-(Trifluoromethyl)acetophenone 98%	233188	5g	$132
4′-(Trifluoromethyl)acetophenone 98%	233188	25g	$206
4'-(Trifluoromethyl)acetophenone >98.0%(GC)	T1784	1g	$20
4'-(Trifluoromethyl)acetophenone >98.0%(GC)	T1784	5g	$41
4'-(Trifluoromethyl)acetophenone	FT28471	0.5kg	$150
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4'-(Trifluoromethyl)acetophenone Properties

Melting point	30-33 °C(lit.)
Boiling point	79-80 °C8 mm Hg(lit.)
Density	0.92
refractive index	1.4604
Flash point	184 °F
storage temp.	Sealed in dry,Room Temperature
form	Low Melting Solid
color	White to faintly yellow
BRN	1870425
InChI	1S/C9H7F3O/c1-6(13)7-2-4-8(5-3-7)9(10,11)12/h2-5H,1H3
InChIKey	HHAISVSEJFEWBZ-UHFFFAOYSA-N
SMILES	CC(=O)c1ccc(cc1)C(F)(F)F
CAS DataBase Reference	709-63-7(CAS DataBase Reference)
FDA UNII	TZ2PGR8637
NIST Chemistry Reference	4-CF3-C6H4-COCH3(709-63-7)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Xi,F

Risk Statements

36/37/38-11

Safety Statements

26-36-37/39-16

WGK Germany

HazardClass

IRRITANT

HS Code

29147090

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2

NFPA 704

	2
2		0

4'-(Trifluoromethyl)acetophenone price More Price(92)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	233188	4′-(Trifluoromethyl)acetophenone 98%	709-63-7	5g	$132	2026-04-30	Buy
Sigma-Aldrich	233188	4′-(Trifluoromethyl)acetophenone 98%	709-63-7	25g	$206	2026-04-30	Buy
TCI Chemical	T1784	4'-(Trifluoromethyl)acetophenone >98.0%(GC)	709-63-7	1g	$20	2026-04-30	Buy
TCI Chemical	T1784	4'-(Trifluoromethyl)acetophenone >98.0%(GC)	709-63-7	5g	$41	2026-04-30	Buy
Biosynth	FT28471	4'-(Trifluoromethyl)acetophenone	709-63-7	0.5kg	$150	2026-06-04	Buy

Product number	Packaging	Price	Buy
233188	5g	$132	Buy
233188	25g	$206	Buy
T1784	1g	$20	Buy
T1784	5g	$41	Buy
FT28471	0.5kg	$150	Buy

4'-(Trifluoromethyl)acetophenone Chemical Properties,Uses,Production

Synthesis

41.6 g of chlorocyclohexane (0.35 mol) were added dropwise to a suspension of 4.65 g of lithium particles (0.68 mol) in 350 g of THF at -55 °C, and an addition time of 2 hours was chosen. After >97% chlorocyclohexane conversion by GC (10 hours), a mixture of 38.3 g of 4-bromotrifluorotoluene (0.170 mol) and 7.0 g of acetonitrile (0.170 mol) was added dropwise at the same temperature for 15 minutes. After stirring for an additional 30 minutes at -50°C, the reaction mixture was slowly thawed to room temperature and subjected to an aqueous workup in a conventional manner. The yield of 4-trifluoromethylacetophenone after distillation was 81%.

Chemical Properties

White to faintly yellow low melting solid

Uses

A labelled acetophenone with selective antimycobacterial activity.

General Description

The enantioselective addition of dialkylzinc to 4′-(trifluoromethyl)acetophenone mediated by 1,2-bis(hydroxycamphorsulfonamido)cyclohexenes in the presence of titanium tetraisopropoxide has been investigated. Phosphorescence emission spectra of 4′-(trifluoromethyl)acetophenone has been studied using pulsed source phosphorimetry.

Purification Methods

Purify the ketone by distillation or sublimation in vacuo.[Beilstein 7 IV 1404.]

4'-(Trifluoromethyl)acetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

1,3-Dioxolane, 2-(bromomethyl)-2-[4-(trifluoromethyl)phenyl]- 4-(TRIFLUOROMETHYL)PHENYLGLYOXAL HYDRATE 2-METHYL-1-[4-(TRIFLUOROMETHYL)PHENYL]PROPAN-1-ONE 4'-(TRIFLUOROMETHYL)PROPIOPHENONE 4-(Trifluoromethyl)phenacyl bromide

5(6H)-Quinolinone, 2-cyclopentyl-4-(4-fluorophenyl)-7,8-dihydro-7,7-dimethyl-3-[4-(trifluoromethyl)benzoyl]- 4,4,4-TRIFLUORO-1-(4-TRIFLUOROMETHYLPHENYL)-1,3-BUTANEDIONE SCH 350581

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4'-(Trifluoromethyl)acetophenone Suppliers

Global( 340)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13901	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2994	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569262 +86-15003564040	1056@dideu.com	China	3970	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58
Jinan Carbotang Biotech Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58

View Lastest Price from 4'-(Trifluoromethyl)acetophenone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-02-02	4'-(Trifluoromethyl)acetophenone 709-63-7		10mg	99%	2000tons	Shaanxi Dideu Medichem Co. Ltd
2022-01-04	4-(Trifluoromethyl)acetophenone 709-63-7		1g	98%min	100kgs/month	Shanghai Rlavie Technology Co ltd
2021-11-15	4'-(TrifluoroMet 709-63-7	$10.80	1KG	99%	500ton/Month	Qiuxian Baitai New Material Co., LTD

4'-(Trifluoromethyl)acetophenone
709-63-7
99%
Shaanxi Dideu Medichem Co. Ltd

4-(Trifluoromethyl)acetophenone
709-63-7
98%min
Shanghai Rlavie Technology Co ltd

4'-(TrifluoroMet
709-63-7
$10.80
99%
Qiuxian Baitai New Material Co., LTD

4'-(Trifluoromethyl)acetophenone Spectrum

4'-(Trifluoromethyl)acetophenone(709-63-7)MS 4'-(Trifluoromethyl)acetophenone(709-63-7)¹HNMR 4'-(Trifluoromethyl)acetophenone(709-63-7)¹³CNMR 4'-(Trifluoromethyl)acetophenone(709-63-7)IR1 4'-(Trifluoromethyl)acetophenone(709-63-7)IR2 4'-(Trifluoromethyl)acetophenone(709-63-7)Raman

709-63-7(4'-(Trifluoromethyl)acetophenone)Related Search:

4-Trifluoromethylphenol 4-Fluoroacetophenone 3'-Methylacetophenone Trifluoromethanesulfonic anhydride Phenylhydrazine

3-（trifluoromethyl) Cinnamaldehyde 3-(Trifluoromethyl)benzaldehyde Trifluoroacetophenone 4-Trifluoromethylphenylboronic acid 4'-Bromoacetophenone

4-(TRIFLUOROMETHYL)PHENYLACETONITRILE (Trifluoromethyl)trimethylsilane Chalcone PHENYL VALERATE Acetophenone

4'-Methylacetophenone 4'-Hydroxyacetophenone Trifluoro-p-tolunitrile

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1-[4-(Trifluoromethyl)phenyl]ethanone Ethanone, 1-[4-(trifluoromethyl)phenyl]- 1-[4-(Trifluoromethyl)phenyl]ethan-1-one 4-ACETYLBENZOFLUORIDE 4-ACETYLBENZOTRIFLUORIDE P-TRIFLUOROMETHYLACETOPHENONE 4'-(Trifluoromethyl)acetophenone,98% 4-(trifluoromehtyl)acetophenone 4'-(Trifluoromethyl)acetophenone 98% 4'-(Trifluoromethyl)acetophenone,99% 4-Acetylbe 4-(trifluromethyl)acetophenone 1-ó4-(Trifluoromethyl)phenyl!ethan-1-one, 97% 4′-(Trifluoromethyl)acetophenone,4-Acetylbenzotrifluoride p-Trifluoromethylacetophenone, min. 98% 4-TRIFLUOROMETHYL BENZYLDEHYDE (4-TrifluoroMethylphenyl) Methyl Ketone 1-[4-(TrifluoroMethyl)phenyl]-1-ethanone 1-Acetyl-4-(trifluoroMethyl) benzene NSC 88346 On the trifluoroMethyl 1-[4-(Trifluoromethyl)phenyl]ethan-1-one, 4-Acetylbenzotrifluoride 4'-(TrifluoroMethyl)acetophenone, 97+% 4′-(trifuoromethyl)acetophenone 1-(4-Trifluoromethyl-phenyl)-ethanone 4'-(Trifluoromethyl)acetophenone 4′-(Trifluoromethyl)acetophenone, CAS 709-63-7 4-(TRIFLUOROMETHYL)ACETOPHENONE 709-63-7 706-63-7 CF3C6H4COCH3 Aromatic Acetophenones & Derivatives (substituted) ketone Trifluoromethylbenzene serise Aromatics bc0001

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