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2-AMINO-3-CYANOTHIOPHENE

2-AMINO-3-CYANOTHIOPHENE structure

CAS No.: 4651-82-5

Chemical Name:: 2-AMINO-3-CYANOTHIOPHENE

Synonyms: 2-AMINOTHIOPHENE-3-CARBONITRILE;AKOS 92285;AKOS B014697;Compound Fr16663;BUTTPARK 36\18-34;AKOS BBS-00006621;TIMTEC-BB SBB005484;ART-CHEM-BB B014697;2-AMINO-3-CYANOTHIOPHENE;2-AMINIO-3-CYANOTHIOPHENE

CBNumber:: CB9733617

Molecular Formula:: C5H4N2S

Molecular Weight:: 124.16

MDL Number:: MFCD00706298

MOL File:: 4651-82-5.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 05:57:38

Product description	Number	Pack Size	Price
2-Aminothiophene-3-carbonitrile 97%	681067	1g	$62.9
2-Aminothiophene-3-carbonitrile 97%	681067	5g	$126
2-Amino-3-cyanothiophene >98.0%(GC)	A2488	5g	$61
2-Amino-3-cyanothiophene Asreported	261131	25g	$363
2-Amino-3-cyanothiophene Asreported	261131	50g	$581
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2-AMINO-3-CYANOTHIOPHENE Properties

Melting point	104-108 °C
Boiling point	318℃
Density	1.33
Flash point	146℃
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
form	powder to crystalline
pka	-0.28±0.10(Predicted)
color	White to Light yellow to Light orange
InChI	InChI=1S/C5H4N2S/c6-3-4-1-2-8-5(4)7/h1-2H,7H2
InChIKey	XVGHZFWFGXDIOU-UHFFFAOYSA-N
SMILES	C1(N)SC=CC=1C#N
CAS DataBase Reference	4651-82-5(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H302-H315-H318-H335

Precautionary statements

P280-P301+P312+P330-P302+P352-P305+P351+P338+P310

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Hazard Codes

Xi,Xn

Risk Statements

20/21/22-36/37/38-41-37/38-22

Safety Statements

36/37-39-26

RIDADR

3439

WGK Germany

HazardClass

IRRITANT

HS Code

2934999090

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		0

2-AMINO-3-CYANOTHIOPHENE price More Price(114)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	681067	2-Aminothiophene-3-carbonitrile 97%	4651-82-5	1g	$62.9	2026-04-30	Buy
Sigma-Aldrich	681067	2-Aminothiophene-3-carbonitrile 97%	4651-82-5	5g	$126	2026-04-30	Buy
TCI Chemical	A2488	2-Amino-3-cyanothiophene >98.0%(GC)	4651-82-5	5g	$61	2026-04-30	Buy
Usbiological	261131	2-Amino-3-cyanothiophene Asreported	4651-82-5	25g	$363	2026-06-03	Buy
Usbiological	261131	2-Amino-3-cyanothiophene Asreported	4651-82-5	50g	$581	2026-06-03	Buy

Product number	Packaging	Price	Buy
681067	1g	$62.9	Buy
681067	5g	$126	Buy
A2488	5g	$61	Buy
261131	25g	$363	Buy
261131	50g	$581	Buy

2-AMINO-3-CYANOTHIOPHENE Chemical Properties,Uses,Production

Uses

2-Aminothiophene-3-carboxynitrile is a pharmaceutical intermediate. Due to its important role in immunity, HPK1 inhibitors play an important role in malignant solid tumors or hematological malignancies (such as acute myeloid leukemia, bladder epithelial carcinoma, breast cancer, colon cancer, lung cancer, pancreatic cancer, melanoma), autoimmune diseases (such as systemic lupus erythematosus, psoriatic arthritis), and inflammatory responses.

Chemical Properties

white to light yellow crystal powder

2-AMINO-3-CYANOTHIOPHENE synthesis

Synthesis of 2-AMINO-3-CYANOTHIOPHENE from Acetaldehyde and Malononitrile

2-AMINO-3-CYANOTHIOPHENE Preparation Products And Raw materials

Raw materials

2,5-Dihydroxy-1,4-dithiane Acetaldehyde Malononitrile

Preparation Products

5-bromo-4-chlorothieno[2,3-d]pyrimidine 2,4-Dihydroxythieno[2,3-d]pyrimidine 4-chloro-2-(chloromethyl)thieno[2,3-d]pyrimidine 4-BROMO-3-(4H-1,2,4-TRIAZOL-3-YL)THIOPHEN-2-AMINE 4-Chloro-2-(trifluoroMethyl)thieno[2,3-d]pyriMidine

5-BroMo-4-hydrazinylthieno[2,3-d]pyriMidine

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2-AMINO-3-CYANOTHIOPHENE Suppliers

Global( 196)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8828	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10236	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
Hubei Ipure Biology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from 2-AMINO-3-CYANOTHIOPHENE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-18	2-AMINO-3-CYANOTHIOPHENE 4651-82-5	$1.10	1g	99.00%	100 Tons	Dideu Industries Group Limited
2024-02-19	2-Amino-3-cyanothiophene 4651-82-5	$350.00	1g	98	500 Kg	R&D Scientific Inc.
2019-07-06	2-AMINO-3-CYANOTHIOPHENE 4651-82-5	$1.00	1KG	99%	20kg	Career Henan Chemical Co

2-AMINO-3-CYANOTHIOPHENE
4651-82-5
$1.10
99.00%
Dideu Industries Group Limited

2-Amino-3-cyanothiophene
4651-82-5
$350.00
98
R&D Scientific Inc.

2-AMINO-3-CYANOTHIOPHENE
4651-82-5
$1.00
99%
Career Henan Chemical Co

2-AMINO-3-CYANOTHIOPHENE Spectrum

2-AMINO-3-CYANOTHIOPHENE(4651-82-5)¹HNMR

4651-82-5(2-AMINO-3-CYANOTHIOPHENE)Related Search:

2-AMINO-3-CYANO-4-METHYL-5-CARBMETHOXY THIOPHENE 2-AMINO-6-METHYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBONITRILE 3-Thiophenecarbonitrile METHYL 3-AMINO-4-CYANOTHIOPHENE-2-CARBOXYLATE 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBONITRILE

2-AMINO-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBONITRILE N1-(3-CYANO-4-METHYL-2-THIENYL)-2-CHLOROACETAMIDE 2-AMINO-4,7-DIHYDRO-5H-THIENO[2,3-C]PYRAN-3-CARBONITRILE 2-AMINO-5,6,7,8-TETRAHYDRO-4H-CYCLOHEPTA[B]THIOPHENE-3-CARBONITRILE METHYL 3-AMINO-4-CYANO-5-(DIMETHYLAMINO)THIOPHENE-2-CARBOXYLATE

2-AMINO-6-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE-3-CARBONITRILE METHYL 3-AMINO-4-CYANO-5-PIPERIDINOTHIOPHENE-2-CARBOXYLATE 2-CHLORO-N-(3-CYANO-2-THIENYL)ACETAMIDE N'-(6-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-3-CYANO-4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDIN-2-YL)-N,N-DIMETHYLIMINOFORMAMIDE AKOS 93048

2-amino-4,5-dihydronaphtho[2,1-b]thiophene-1-carbonitrile TIMTEC-BB SBB009939 6-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-(([4-(DIMETHYLAMINO)PHENYL]METHYLENE)AMINO)-4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE-3-CARBONITRILE

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ART-CHEM-BB B014697 BUTTPARK 36\18-34 2-AMINO-3-THIOPHENECARBONITRILE 2-AMINO-3-CYANOTHIOPHENE AKOS B014697 AKOS 92285 AKOS BBS-00006621 TIMTEC-BB SBB005484 2-AMINIO-3-CYANOTHIOPHENE 2-Aminothiophene-3-carbonitrile 97% 2-aminothiophene-3-carbonitrile(SALTDATA: FREE) 3-Thiophenecarbonitrile, 2-amino- JR-8818, 2-Amino-3-cyanothiophene, 97% 2-Aminothiophene-3ART-CHEM-BB B014697 2-Amino-3-cyanothiophene> 2-AMINO-3-CYANOTHIOPHENE ISO 9001：2015 REACH Compound Fr16663 2-AMINOTHIOPHENE-3-CARBONITRILE 4651-82-5 C5H4N2S Heterocyclic Building Blocks Thiophenes Building Blocks Amines Thiophenes & Benzothiophenes Heterocyclic Compounds Thiophenes & Benzothiophenes Building Blocks Heterocyclic Building Blocks Thiophenes

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