ChemicalBook >> CAS DataBase List >>4-Fluorophenyl sulfone
4-Fluorophenyl sulfone
- CAS No.
- 383-29-9
- Chemical Name:
- 4-Fluorophenyl sulfone
- Synonyms
- BIS(4-FLUOROPHENYL) SULFONE;fone;4,4'-DIFLUORODIPHENYL SULFONE;4,4'-Sulfonylbis(fluorobenzene);NSC-87584;JACS-383-29-9;4-Fluorophenyl sulfo;P-FLUOROPHENYL SULFONE;4-FLUOROPHENYL SULFONE;4-FLUOROPHENYL SULPHONE
- CBNumber:
- CB9768439
- Molecular Formula:
- C12H8F2O2S
- Molecular Weight:
- 254.25
- MDL Number:
- MFCD00000350
- MOL File:
- 383-29-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 06:09:16
| Product description | Number | Pack Size | Price |
| Bis(4-fluorophenyl) sulfone 99% | F15145 | 25g | $204 |
| Bis(4-fluorophenyl) sulfone for synthesis | 8.41368 | 5G | $101 |
| Bis(4-fluorophenyl) Sulfone >99.0%(GC) | D0537 | 10g | $108 |
| Bis(4-fluorophenyl) Sulfone >99.0%(GC) | D0537 | 25g | $188 |
| 4,4'-Difluorodiphenyl sulphone 98% | PC2752 | 25g | $21 |
| More product size | |||
| Melting point | 98-100 °C(lit.) |
|---|---|
| Boiling point | 367.9±27.0 °C(Predicted) |
| Density | 1.3538 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | soluble in Methanol |
| form | Crystals or Powder |
| color | White to brown |
| BRN | 1970911 |
| InChI | InChI=1S/C12H8F2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H |
| InChIKey | PLVUIVUKKJTSDM-UHFFFAOYSA-N |
| SMILES | S(C1=CC=C(F)C=C1)(C1=CC=C(F)C=C1)(=O)=O |
| CAS DataBase Reference | 383-29-9(CAS DataBase Reference) |
| FDA UNII | KW93VS9RT8 |
| NIST Chemistry Reference | Sulfone, bis(4-fluorophenyl)-(383-29-9) |
| EPA Substance Registry System | Benzene, 1,1'-sulfonylbis[4-fluoro- (383-29-9) |
| UNSPSC Code | 12352119 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H331-H302-H315-H319-H411 | |||||||||
| Precautionary statements | P501-P261-P273-P270-P271-P264-P280-P302+P352-P391-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P304+P340+P311-P403+P233-P405 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29309070 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
4-Fluorophenyl sulfone price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | F15145 | Bis(4-fluorophenyl) sulfone 99% | 383-29-9 | 25g | $204 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.41368 | Bis(4-fluorophenyl) sulfone for synthesis | 383-29-9 | 5G | $101 | 2026-04-30 | Buy |
| TCI Chemical | D0537 | Bis(4-fluorophenyl) Sulfone >99.0%(GC) | 383-29-9 | 10g | $108 | 2026-04-30 | Buy |
| TCI Chemical | D0537 | Bis(4-fluorophenyl) Sulfone >99.0%(GC) | 383-29-9 | 25g | $188 | 2026-04-30 | Buy |
| Apolloscientific | PC2752 | 4,4'-Difluorodiphenyl sulphone 98% | 383-29-9 | 25g | $21 | 2026-06-04 | Buy |
4-Fluorophenyl sulfone Chemical Properties,Uses,Production
Chemical Properties
white to brown crystals or powder
Uses
4-Fluorophenylsulfone was used in substitution reactions with deprotonated amines.
Synthesis
824-80-6
383-29-9
GENERAL PROCEDURE: A mixture of sodium aryl sulfite (1 mmol), copper(II) acetate (0.5 mmol) and acetonitrile (1 mL) was stirred in air at 60°C for 3 hours. After completion of the reaction, the mixture was cooled to room temperature and filtered through filter paper. Subsequently, the organic phase was evaporated under reduced pressure and the residue was purified by fast column chromatography (silica gel, eluent ethyl acetate/petroleum ether=1/10) to afford the target product 4,4'-difluorodiphenyl sulfone. All products were known compounds and their structures were confirmed by 1H NMR, 13C NMR and high resolution mass spectrometry (HRMS).
References
[1] Journal of Chemical Research, 2014, vol. 38, # 5, p. 265 - 268
4-Fluorophenyl sulfone Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 270)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3955 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14025 | 58 |
| Speranza Chemical Co., Ltd. | +86-86-075521030354 +86-18688942810 | sophieliu@speranzachem.com | China | 923 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| Zhengzhou Alfa Chemical Co.,Ltd | +86-18530059196 | sale04@alfachem.cn | China | 9612 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 4-Fluorophenyl sulfone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | 4,4'-Sulfonylbis(fluorobenzene)
383-29-9
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2024-06-26 | 4-Fluorophenyl sulfone
383-29-9
|
$1.00 | 1KG | 99% | 20t | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-07-06 | 4-Fluorophenyl sulfone
383-29-9
|
$292.80-308.60 | 20KG | 99% | 100KG | Career Henan Chemical Co |
-
- 4,4'-Sulfonylbis(fluorobenzene)
383-29-9
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 4-Fluorophenyl sulfone
383-29-9
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 4-Fluorophenyl sulfone
383-29-9
- $292.80-308.60
- 99%
- Career Henan Chemical Co
383-29-9(4-Fluorophenyl sulfone)Related Search:
1,1’-sulfonylbis[4-fluoro-benzen
1-Fluoro-4-[(4-fluorophenyl)sulfonyl]benzene
Benzene, 1,1'-sulfonylbis*4-fluoro-
Benzene, 1,1'-sulfonylbis[4-fluoro-
Sulfone, bis(p-fluorophenyl)
P-FLUOROPHENYL SULFONE
4-FLUOROPHENYL SULPHONE
4-FLUOROPHENYL SULFONE
4,4-DIFLUORODIPHENYL SULFONE
4,4-DIFLUOROBIPHENYL SULFONE
4,4'-DIFLUOROPHENYL SULFONE
BIS(P-FLUOROPHENYL) SULFONE
BIS(4-FLUOROPHENYL) SULPHONE
Bis(4-fluorophenyl)sulfone,98+%
4,4-Difluorobiphenyl sulphone
4,4-Difluorodiphenyl sulphone~4-Fluorophenyl sulphone
bis(p-fluorophenyl)sulphone
4,4μ-Difluorodiphenyl sulfone, 4-Fluorophenyl sulfone
4,4'-Difluorobiphenyl sulphone 98%
4,4'-Difluorobiphenylsulphone98%
1,1'-sulfonylbis[4-fluoro-benzene]
4-FLUOROPHENYLSULPHONE/4,4''-DIFLUOROPHENYLSULFONE
4-Fluorophenyl sulfone,99%
4-Fluorophenyl sulfo
1-fluoro-4-[(4-fluorobenzene)sulfonyl]benzene
4-Fluorophenyl sulfone, 99% 25GR
NSC-87584
1,1'-Sulphonylbis(4-fluorobenzene), Bis(4-fluorophenyl) sulphone
4,4'-Difluorodiphenyl sulphone 98%
Bis(4-fluorophenyl) sulfone 99%
JACS-383-29-9
(2R)-2-chloro-1-(10-phenothiazinyl)-1-propanone
Bis(4-fluorophenyl) Sulfone >
BIS(4-FLUOROPHENYL) SULFONE FOR SYNTHESI
4,4'-Difluorodiphenyl sulphone
Bis(4-fluorophenyl)sulfone, 99%min
4,4'-Difluorodiphenyl sulphone
4,4'-Sulfonylbis(fluorobenzene)
4,4'-DIFLUORODIPHENYL SULFONE
BIS(4-FLUOROPHENYL) SULFONE
fone
383-29-9
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