(3beta,24S)-stigmast-5-en-3-ol
- CAS No.
- 83-47-6
- Chemical Name:
- (3beta,24S)-stigmast-5-en-3-ol
- Synonyms
- gamma-sitosterol;Clionasterol;beta-Dihydrofucosterol;g-Sitosterol;Einecs 201-481-1;(24S)-Stigmast-5-en-3β-ol;22,23-Dihydroporiferasterol;(3b,24S)-stigmast-5-en-3-ol;Stigmast-5-en-3-ol, (3b,24S)-;Stigmast-5-en-3-ol, (3β,24S)-
- CBNumber:
- CB9932128
- Molecular Formula:
- C29H50O
- Molecular Weight:
- 414.71
- MDL Number:
- MOL File:
- 83-47-6.mol
| Product description | Number | Pack Size | Price |
| (3b,24S)-Stigmast-5-En-3-Ol | FS165756 | 1g | $11682 |
| Boiling point | 473.52°C (rough estimate) |
|---|---|
| Density | 0.9540 (rough estimate) |
| refractive index | 1.5000 (estimate) |
| Melting point | 147 °C |
| pka | 15.03±0.70(Predicted) |
| FDA UNII | 5LI01C78DD |
(3beta,24S)-stigmast-5-en-3-ol Chemical Properties,Uses,Production
Uses
γ-Sitosterol is an inhibitor for c-Myc. γ-Sitosterol inhibits the proliferation of cancer cell MCF-7 and A549 with IC50 of 240.73 μg/mL and 696.6 μg/mL, arrests the cell cycle at G2/M phase, and induces apoptosis. γ-Sitosterol upregulates the expression of cell cycle regulators cyclin B/E[1].
Definition
ChEBI: Clionasterol is a member of the class of phytosterols that is poriferast-5-ene carrying a beta-hydroxy substituent at position 3. It has a role as a plant metabolite and a marine metabolite. It is a 3beta-sterol, a member of phytosterols and a 3beta-hydroxy-Delta(5)-steroid. It derives from a hydride of a poriferastane.
References
[1] Sundarraj S, et al., γ-Sitosterol from Acacia nilotica L. induces G2/M cell cycle arrest and apoptosis through c-Myc suppression in MCF-7 and A549 cells. J Ethnopharmacol. 2012 Jun 14;141(3):803-9. DOI:10.1016/j.jep.2012.03.014
(3beta,24S)-stigmast-5-en-3-ol Preparation Products And Raw materials
Raw materials
Preparation Products
(3beta,24S)-stigmast-5-en-3-ol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21586 | 55 |
| Biosynth Biological Technology (Suzhou) Co Ltd | -- | sales@biosynth.com | China | 6051 | 58 |
| Supplier | Advantage |
|---|---|
| Henan Tianfu Chemical Co.,Ltd. | 55 |
| Biosynth Biological Technology (Suzhou) Co Ltd | 58 |
