4-Bromo-1-fluoro-2-iodobenzene
- CAS No.
- 116272-41-4
- Chemical Name:
- 4-Bromo-1-fluoro-2-iodobenzene
- Synonyms
- 3-Iodo-4-fluorobromobenzene;5-Bromo-2-fluoroiodobenzene;2-Iodo-4-bromofluorobenzene;2-fluoro-5-bromo-iodobenzene;4-FLUORO-3-IODO BROMOBENZENE;5-Bromo-2-fluoro-1-iodobenzene;4-Bromo-1-fluoro-2-iodobenzene;4-Bromo-1-fluoro-4-iodobenzene;5-Bromo-2-fluoroiodobenzene 99%;Benzene, 4-bromo-1-fluoro-2-iodo-
- CBNumber:
- CB9971774
- Molecular Formula:
- C6H3BrFI
- Molecular Weight:
- 300.89
- MDL Number:
- MFCD07368751
- MOL File:
- 116272-41-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-Bromo-2-fluoroiodobenzene 99% | PC2532 | 25g | $21 |
| 5-Bromo-2-fluoroiodobenzene 99% | PC2532 | 100g | $52 |
| 5-Bromo-2-fluoroiodobenzene 99% | PC2532 | 500g | $237 |
| 5-Bromo-2-fluoroiodobenzene 99% | PC2532 | 25g | $21 |
| 5-Bromo-2-fluoroiodobenzene 99% | PC2532 | 100g | $52 |
| More product size | |||
| Boiling point | 247.4±25.0 °C(Predicted) |
|---|---|
| Density | 2.281 |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| form | liquid |
| color | Clear, colourless |
| Sensitive | Light Sensitive |
| InChI | InChI=1S/C6H3BrFI/c7-4-1-2-5(8)6(9)3-4/h1-3H |
| InChIKey | JNETZJWWXCLUKM-UHFFFAOYSA-N |
| SMILES | C1(F)=CC=C(Br)C=C1I |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P271-P280 |
| Hazard Codes | Xi |
| HazardClass | IRRITANT |
| HS Code | 2903998090 |
4-Bromo-1-fluoro-2-iodobenzene price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC2532 | 5-Bromo-2-fluoroiodobenzene 99% | 116272-41-4 | 25g | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC2532 | 5-Bromo-2-fluoroiodobenzene 99% | 116272-41-4 | 100g | $52 | 2026-06-04 | Buy |
| Apolloscientific | PC2532 | 5-Bromo-2-fluoroiodobenzene 99% | 116272-41-4 | 500g | $237 | 2026-06-04 | Buy |
| Apolloscientific | PC2532 | 5-Bromo-2-fluoroiodobenzene 99% | 116272-41-4 | 25g | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC2532 | 5-Bromo-2-fluoroiodobenzene 99% | 116272-41-4 | 100g | $52 | 2026-06-04 | Buy |
4-Bromo-1-fluoro-2-iodobenzene Chemical Properties,Uses,Production
Chemical Properties
Yellow crstalline
Uses
4-Bromo-1-fluoro-2-iodobenzene is a polyhalogenated benzene derivative containing substitutable reactive groups of fluorine, bromine and iodine atoms in its molecular structure. It is mainly used as a molecular building block, organic synthesis or pharmaceutical intermediate compound, and is a raw material for the preparation of other aromatic alkanes or heterocyclic compounds.
Synthesis
2924-09-6
116272-41-4
Under argon protection, 5-bromo-2-fluoroaniline (45.6 g, 240 mmol) was dissolved in water (120 mL), stirred and concentrated hydrochloric acid (120 mL) was added slowly. After the reaction mixture was cooled to -20 °C, aqueous sodium nitrite (19.9 g, 288 mmol dissolved in 80 mL of water) was added dropwise. Stirring was continued at -20 °C for 20 min, followed by the addition of aqueous potassium iodide solution (59.8 g, 360 mmol dissolved in 60 mL of water) and stirring was continued for 30 min. After completion of the reaction, the reaction mixture was extracted with hexane and the organic layer was washed sequentially with saturated aqueous sodium bicarbonate and sodium sulfite solutions and dried over anhydrous sodium sulfate. After evaporation of the solvent under reduced pressure, the residue was purified by silica gel column chromatography to afford 5-bromo-2-fluoroiodobenzene (54.6 g, 181 mmol) in 76% yield.
References
[1] Patent: KR2016/18458, 2016, A. Location in patent: Paragraph 0309-0311
[2] Patent: EP2924029, 2015, A1. Location in patent: Paragraph 0130; 0131
4-Bromo-1-fluoro-2-iodobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +8615988602810 | sales@anbuchem.com | China | 3016 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 | sophieliu@speranzachem.com | China | 923 | 55 |
View Lastest Price from 4-Bromo-1-fluoro-2-iodobenzene manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-09-25 | 3-Iodo-4-fluorobromobenzene
116272-41-4
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
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2025-03-21 | 3-Iodo-4-fluorobromobenzene
116272-41-4
|
1KG | 98% | 1000KGS | Zhengzhou Anbu Chem Co.,Ltd | ||
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2019-07-06 | 3-Iodo-4-fluorobromobenzene
116272-41-4
|
$2.00 | 1kg | 99% | Career Henan Chemical Co |
-

- 3-Iodo-4-fluorobromobenzene
116272-41-4
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-

- 3-Iodo-4-fluorobromobenzene
116272-41-4
- $0.00
- 98%
- Zhengzhou Anbu Chem Co.,Ltd
-

- 3-Iodo-4-fluorobromobenzene
116272-41-4
- $2.00
- 99%
- Career Henan Chemical Co
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