ニコチン酸 メチル 化學(xué)特性,用途語,生産方法
外観
白色?褐色, 結(jié)晶又は塊
定義
本品は、ナイアシン(*)のメチルエステルであり、次の化學(xué)式で表される。
參照表示名稱：ナイアシン
溶解性
エタノールに溶け、水にほとんど溶けない。
無機性値/有機性値
145/140
用途
有機合成原料。
化粧品の成分用途
皮膚コンディショニング剤、外用鎮(zhèn)痛剤、香料
効能
血管拡張薬
説明
Methyl nicotinate is a skin irritant in man, in particular producing vasodilatation, which is used on purpose in “rubefacient”, to produce a redness or inflammation for a short period of time, often in lip plumper or other lip products. Methyl nicotinate is also an active ingredient of a number of veterinary preparations intended for topical application as a rubefacient for the treatment of a variety of diseases, such as respiratory diseases, vascular disorders (oedema, haematoma), and rheumatoid disorders in cattle and horses (doses not stated; the concentration in the formulated veterinary medicinal product is 2%).
化學(xué)的特性
Methyl nicotinate is white to brownish crystals or crystalline powder and has a fresh, caramellic, nutty and mild tobacco odor.
天然物の起源
Reported found in ground coffee, roasted filberts, guanabana (Annona muicata L.), roasted peanuts, wild
strawberries, vanilla bean, papaya, guava, plum, beer cognac, soursop, malt, wort, Bourbon vanilla and mountain papaya.
使用
Methyl nicotinate (MN) is the methyl ester of nicotinic acid that is used as an active ingredient, a rubefacient and counter-irritant in over-the-counter topical preparations indicated for the temporary relief of aches and pains in muscles,tendons, and joints. The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation.For veterinary purposes，methyl nicotinate is used to treat respiratory diseases, vascular disorders, rheumatoid arthritis, and muscle and joint pains.Methyl nicotinate can be found in in guava fruit, papaya, strawberry, soursop(Annona muricata), beer, grape brandy, coffee, roasted filbert, roasted peanut and Bourbon vanilla.
一般的な説明
Methyl nicotinate (or nicotinic acid methyl ester) is used as a rubefacient for the relief of pains in muscles, tendons, and joints. It is also used in food as a flavoring agent.
合成
Methyl nicotinate is synthesized from Nicotinyl chloride hydrochloride and and Methanol in presence of Pyridine.
ニコチン酸 メチル 上流と下流の製品情報
原材料
準(zhǔn)備製品