N-[3-(8-モルホリノ-9-オキサ-1,5,7-トリアザ-9H-フルオレン-6-イル)フェニル]-6-アミノニコチンアミド 価格

メーカー	製品番號(hào)	製品説明	CAS番號(hào)	包裝	価格	更新時(shí)間	購(gòu)入

N-[3-(8-モルホリノ-9-オキサ-1,5,7-トリアザ-9H-フルオレン-6-イル)フェニル]-6-アミノニコチンアミド 化學(xué)特性,用途語(yǔ),生産方法

使用

YM 201636 is a phosphatidylinositol phosphate kinase PIP5KIII (PIKfyve) inhibitor and significantly reduces the survival of primary mouse hippocampal neurons in culture. YM-201636 treatment increases the level of the autophagosomal marker protein LC3-II.

一般的な説明

A cell-permeable pyridofuropyrimidine compound that selectively inhibits mammalian type III PtdInsP kinase (IC₅₀ = 33 nM and >5 μM using murine PIKfyve and yeast Fab1, respectively), while exhibiting much reduced activity against p110α (IC₅₀ = 3.3 μM) and little activity against type IIγ PtdInsP kinase even at concentrations as high as 10 μM. Shown to block serum-induced PtdIns(3,5)P₂ production in NIH3T3 cells (80% inhibition at 800 nM) and disrupt cellular endosomal transport in a reversible manner.

N-[3-(8-モルホリノ-9-オキサ-1,5,7-トリアザ-9H-フルオレン-6-イル)フェニル]-6-アミノニコチンアミド 上流と下流の製品情報(bào)

原材料

準(zhǔn)備製品

N-[3-(8-モルホリノ-9-オキサ-1,5,7-トリアザ-9H-フルオレン-6-イル)フェニル]-6-アミノニコチンアミド 生産企業(yè)

名前	電話(huà)番號(hào)	電子メール	國(guó)籍	製品カタログ	優(yōu)位度
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	965	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	9545	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	28292	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471;	sales@sarms4muscle.com	China	10473	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58

371942-69-7(N-[3-(8-モルホリノ-9-オキサ-1,5,7-トリアザ-9H-フルオレン-6-イル)フェニル]-6-アミノニコチンアミド)キーワード:

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• 371942-69-7
• 6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide YM201636
• YM 201636 6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide
• YM201636, >=98%
• YM201636 HCl
• 6-amino-N-(3-(4-morpholinopyrido[3,,2,:4,5]furo[3,2-d]pyrimidin-2-yl)phenyl)nicotinamide
• 3-Pyridinecarboxamide, 6-amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-
• 6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide
• YM 201636
• YM201636/YM-201636
• 3-Pyridinecarboxamide, 6-amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-
• CS-335
• 6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide USP/EP/BP
• 6-amino-N-(3-(4-morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenyl)nicotinamide hydrochloride
• YM-201636 YM201636 PIKfyve Inhibitor
• s1219
• 6-Amino-N-(3-(4-morpholinopyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenyl)nicotinamide
• YM-201636, 10 mM in DMSO
• PIKfyve Inhibitor
• N-[3-(8-モルホリノ-9-オキサ-1,5,7-トリアザ-9H-フルオレン-6-イル)フェニル]-6-アミノニコチンアミド
• 6-アミノ-N-{3-[6-(モルホリン-4-イル)-8-オキサ-3,5,10-トリアザトリシクロ[7.4.0.02,7]トリデカ-1(9),2(7),3,5,10,12-ヘキサエン-4-イル]フェニル}ピリジン-3-カルボキサミド