L-メチオニンスルホキシイミン
L-メチオニンスルホキシイミン 物理性質
- 融點 :
- >210 °C (dec.)(lit.)
- 沸點 :
- 352.2±52.0 °C(Predicted)
- 比重(密度) :
- 1.215 (estimate)
- 屈折率 :
- 1.6430 (estimate)
- 貯蔵溫度 :
- 20-25°C
- 溶解性:
- 水性塩基（わずかに）、ギ酸（わずかに）、水（少量、超音波処理）
- 外見 :
- 結晶性粉末
- 色:
- 白またはほぼ白
- 由來生物:
- synthetic
- 旋光度（Optical Rotation）:
- [α]20/D +10.8 to +14.0°, c = 1 in H2O
- BRN :
- 6175446
- 安定性：:
- 溫度に敏感
- InChI:
- InChI=1S/C5H12N2O3S/c1-11(7,10)3-2-4(6)5(8)9/h4,7H,2-3,6H2,1H3,(H,8,9)/t4-,11/m0/s1
- InChIKey:
- SXTAYKAGBXMACB-DPVSGNNYSA-N
- SMILES:
- C(O)(=O)[C@@H](N)CCS(C)(=O)=N
- CAS データベース:
- 15985-39-4(CAS DataBase Reference)
L-メチオニンスルホキシイミン 価格
もっと(21)
| メーカー |
製品番號 |
製品説明 |
CAS番號 |
包裝 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01TRCM260500 |
L-Methionine [R,S]-Sulfoximine |
15985-39-4 |
5g |
￥187200 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01COBQH-1656 |
L-メチオニンスルホキシイミン
L-Methionine sulfoximine |
15985-39-4 |
1g |
￥127500 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01COBQH-1656 |
L-メチオニンスルホキシイミン
L-Methionine sulfoximine |
15985-39-4 |
5g |
￥445000 |
2024-03-01 |
購入 |
|
関東化學株式會社(KANTO)
|
22720-1A |
Ｌ‐メチオニンスルホキシイミン >98.0%
L‐Methionine sulfoximine >98.0% |
15985-39-4 |
1g |
￥55770 |
2024-07-01 |
購入 |
|
Sigma-Aldrich Japan
|
M5379 |
L-メチオニンスルホキシミン
L-Methionine sulfoximine |
15985-39-4 |
250mg |
￥29700 |
2024-03-01 |
購入 |
L-メチオニンスルホキシイミン 化學特性,用途語,生産方法
化學的特性
White Crystalline Powder
使用
L-Methionine sulfoximine has been used as a potent inhibitor of glutamine synthetase (GS) activity.
Biochem/physiol Actions
As a potent inhibitor of glutamine synthetase activity (GS), this reagent has widely been used as a selection agent for plasmid integration in Chinese hamster ovary (CHO) and other mammalian cell lines. The growing demand for high yield cell banks for production of recombinant proteins for therapeutics has resulted in two major systems for selection of stable and active clones, Methotrexate selection of dihydrofolate reductase (DHFR) overexpressing cells and MSX selection of glutamine synthetase overexpressing cells. Cells are grown in the absence of glutamine in the media and inhibition of the endogenous activity of glutamine synthetase results in cell death for cells lacking overexpression. The MSX-glutamine synthetase selection mechanism provides benefits over that of the Methotrexate-DHFR system in that it typically requires a single amplification step and results in significant reduction of time to produce high stability, highly amplified clones. L-Methionine sulfoximine (MSX) enhances NH3 production in seedling leaves wheat, barley, corn and sorghum plants by inhibiting GS activity. MSX increases ornithine decarboxylase activity and decreases the survival rate in a model of transient cerebral ischemia.
L-メチオニンスルホキシイミン 上流と下流の製品情報
原材料
準備製品
L-メチオニンスルホキシイミン 生産企業(yè)
Global( 204)Suppliers
L-メチオニンスルホキシイミン スペクトルデータ(1HNMR、FT-IR、IR、Raman)
15985-39-4(L-メチオニンスルホキシイミン)キーワード:
- 15985-39-4
- 2-AMINO-4-(S-METHYLSULFONIMIDOSYL)BUTANOIC ACID
- L-S-[3-AMINO-3-CARBOXYPROPYL]-S-METHYLSULFOXIMINE
- L-METHIONINE SULFOXIMINE
- L-S-[3-Amino-3-carboxypropyl]-S-methyl-[R,S]-sulfoximine
- L-Methionine sulfoximine, 98+%
- Butanoic acid, 2-aMino-4-(S-MethylsulfoniMidoyl)-, (2S)-
- METHIONINE SULFOXIMINE (L)
- Butanoic acid, 2-amino-4-(S-methylsulfonimidoyl)- (9CI)
- Methionine-DL-sulfoximine, DL-
- Methionine-rs-sulfoximine, L-
- Sulfoximine, S-(3-amino-3-carboxypropyl)-S-methyl-, DL-
- -2-Amino-4-(S-methylsulfonimidoyl)
- 2-amino-4-(methylsulfonimidoyl)butyric acid
- L-Methionine Sulfoxime
- L-Methionine sulfoxiimine
- L-Methionin-sulfoximine
- (2S)-2-amino-4-[imino(methyl)oxo-λ?-sulfanyl]butanoic acid
- L-Methionine-(S,R)-Sulfoximine
- L-METHIONINE SULFOXIMINE USP/EP/BP
- "L-Methionine [R,S]-Sulfoximine-13C6"
- (2S)-2-amino-4-(methylsulfonimidoyl)butanoic acid
- L-METHIONINE-DL-SULFOXIMINE
- L-Methionine [R,S]-Sulfoximine
- (2S)-2-Amino-4-(S-methylsulfonimidosyl)butanoic acid
- inhibit,Inhibitor,L Methionine DL sulfoximine,LMethionineDLsulfoximine
- MSX (L-Methionine-DL-sulfoximine)
- L-Methionine sulfoximine
- H-Met(Sulfoximine)-OH
- MSX
- L-メチオニンスルホキシイミン
- L‐メチオニンスルホキシイミン
- 2-アミノ-4-(S-メチルスルホンイミドイル)ブタン酸