ロフェプラミン 価格 もっと(7)

メーカー	製品番號	製品説明	CAS番號	包裝	価格	更新時間	購入
富士フイルム和光純薬株式會社(wako)	W01TRCL469380	ロフェプラミン Lofepramine	23047-25-8	50mg	￥160300	2023-06-01	購入
富士フイルム和光純薬株式會社(wako)	W01TOC2545	ロフェプラミン Lofepramine	23047-25-8	50mg	￥213000	2023-06-01	購入
富士フイルム和光純薬株式會社(wako)	W01TRCL469380	ロフェプラミン Lofepramine	23047-25-8	5mg	￥34500	2024-03-01	購入
富士フイルム和光純薬株式會社(wako)	W01TRCL469380	ロフェプラミン Lofepramine	23047-25-8	10mg	￥45600	2024-03-01	購入
富士フイルム和光純薬株式會社(wako)	W01TRCL469380	ロフェプラミン Lofepramine	23047-25-8	25mg	￥90200	2023-06-01	購入

ロフェプラミン 化學(xué)特性,用途語,生産方法

効能

抗うつ薬, セロトニン?ノルアドレナリン再取り込み阻害薬

説明

Lofepramine is a first generation tricyclic antidepressant that is extensively metabolized to desipramine. It potently inhibits serotonin and norepinephrine transporters (K_ds = 70 and 5.4 nM, respectively) and less potently antagonizes serotonin, histamine, and muscarinic receptors.

化學(xué)的特性

Light Yellow Solid

生物活性

Serotonin and noradrenalin re-uptake inhibitor (SNRI) that is metabolized to desipramine. Produces inhibition of liver tryptophan pyrollase activity in vitro and displays antidepressant properties in vivo .

作用機序

Lofepramine differs from imipramine by the attachment of a p-chlorophenacyl moiety to the N-aminopropyl side chain. This change confers enhanced lipophilicity and the potential of more rapid distribution into the CNS with greater in vitro affinity and selectivity for NET. Its mechanism of antidepressant action is attributed to its rapid metabolism to the secondary amine metabolite, desipramine, which selectively inhibits the neuronal uptake of NE.

ロフェプラミン 上流と下流の製品情報

原材料

準備製品

ロフェプラミン 生産企業(yè)

名前	電話番號	電子メール	國籍	製品カタログ	優(yōu)位度
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42056	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.	+8618950047208	ellena@amitychem.com	China	43414	58
DAYANG CHEM (HANGZHOU) CO.,LTD	+86-88938639 +86-17705817739	info@dycnchem.com	China	53803	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58
J & K SCIENTIFIC LTD.	18210857532; 18210857532	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15838	69
LGM Pharma	1-(800)-881-8210	inquiries@lgmpharma.com	United States	2123	70

23047-25-8(ロフェプラミン)キーワード:

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• 23047-25-8
• LOFEPRAMINE
• Gamanil
• 1-(4-Chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]methylamino]ethanone
• 4'-Chloro-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl-methylamino]acetophenone
• Amplit
• Leo 640
• Lopramine
• 1-(4-Chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenz(Z)[b,f]azepin-5-yl)propyl]methylamino]ethanone
• Ethanone, 1-(4-chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]methylamino]-
• 1-(4-Chlorophenyl)-2-((3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)(methyl)amino)ethan-1-one
• Inhibitor,inhibit,Lofepramine
• 2-[(3-{2-azatricyclo[9.4.0.03,?]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl}propyl)(methyl)amino]-1-(4-chlorophenyl)ethan-1-one
• Lofepramine in methanol
• Lofepramine, 10 mM in DMSO
• Lofepramine - Bio-X ?
• ロフェプラミン
• 4′-クロロ-α-[[3-(10,11-ジヒドロ-5H-ジベンゾ[b,f]アゼピン-5-イル)プロピル]メチルアミノ]アセトフェノン
• 4′-クロロ-α-[N-メチル-N-[3-(10,11-ジヒドロ-5H-ジベンゾ[b,f]アゼピン-5-イル)プロピル]アミノ]アセトフェノン
• ロプラミン
• N-メチル-N-[2-(4-クロロフェニル)-2-オキソエチル]-3-[(10,11-ジヒドロ-5H-ジベンゾ[b,f]アゼピン)-5-イル]プロピルアミン
• 1-(4-クロロフェニル)-2-[[3-[(10,11-ジヒドロ-5H-ジベンゾ[b,f]アゼピン)-5-イル]プロピル]メチルアミノ]エタノン
• 1-(4-クロロフェニル)-2-[[3-(10,11-ジヒドロ-5H-ジベンゾ[b,f]アゼピン-5-イル)プロピル]メチルアミノ]エタノン
• 2-[(3-{2-アザトリシクロ[9.4.0.03,8]ペンタデカ-1(15),3,5,7,11,13-ヘキサエン-2-イル}プロピル)(メチル)アミノ]-1-(4-クロロフェニル)エタン-1-オン