シレンギチド
シレンギチド 物理性質(zhì)
- 比重(密度) :
- 1.41±0.1 g/cm3(Predicted)
- 貯蔵溫度 :
- -20°C
- 溶解性:
- ≥29.43 mg/mL in DMSO; ≥22.56 mg/mL in H2O
- 外見 :
- 粉
- 酸解離定數(shù)(Pka):
- 4.01±0.10(Predicted)
- 色:
- 白からベージュ
- 水溶解度 :
- Soluble to 10 mg/ml in water
- InChIKey:
- AMLYAMJWYAIXIA-MAVOJUFWNA-N
- SMILES:
- N1(C)[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CC2C=CC=CC=2)C1=O |&1:2,9,24,32,r|
| メーカー |
製品番號 |
製品説明 |
CAS番號 |
包裝 |
価格 |
更新時(shí)間 |
購入 |
|
Sigma-Aldrich Japan
|
SML1594 |
≥98% (HPLC)
Cilengitide trifluoroacetic acid salt ≥98% (HPLC) |
188968-51-6 |
25mg |
￥110000 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
SML1594 |
≥98% (HPLC)
Cilengitide trifluoroacetic acid salt ≥98% (HPLC) |
188968-51-6 |
5mg |
￥27400 |
2018-12-25 |
購入 |
シレンギチド 化學(xué)特性,用途語,生産方法
効能
血管新生阻害薬, インテグリン拮抗薬
使用
Cilengitide trifluoroacetic acid salt has been used as an inhibitor of integrin αvβ5.
Biochem/physiol Actions
It exhibits antitumor activity in glioblastoma multiforme tumors. Integrins are heterodimers of α and β chain. They are transmembrane receptors which are responsible for cell-to-cell and cell-extracellular matrix interactions. They control tumor angiogenesis, invasion and migration.
シレンギチド 上流と下流の製品情報(bào)
原材料
準(zhǔn)備製品
シレンギチド 生産企業(yè)
Global( 229)Suppliers
188968-51-6(シレンギチド)キーワード:
- 188968-51-6
- Cyclo(Arg-Gly-Asp-D-Phe-N-Me-Val)
- c(RGDf(NMe)V)
- 2-((2S,5R,8S,11S)-5-Benzyl-11-(3-guanidinopropyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1
- Cilengitide, >=98%
- 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid
- Cyclo(L-arginylglycyl-L-aspartyl-D-phenylalanyl-N-methyl-L-valyl)
- Cilengitide(EMD121974,NSC-707544)
- Cilengitide
- NSC 707544
- D03497
- EMD 12197
- EMD 12197;EMD-85189;EMD-121974;NSC-707544;D03497
- EMD-85189
- 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]aceticaci
- cilengitide USP/EP/BP
- C(RGDf-Me-V)
- EMD 121974;EMD-121974;EMD121974
- CS-1500
- CS-2674
- Cilengitide (EMD 121974)
- 2-((2S,5R,8S,11S)-5-Benzyl-11-(3-guanidinopropyl)-8-isopropyl-7-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid
- cyclo(RGDf-NMe-V)
- Cilengitide, 10 mM in DMSO
- シレンギチド
- 2-[(2S,5R,8S,11S)-5-ベンジル-11-(3-カルバムイミドアミドプロピル)-7-メチル-3,6,9,12-テトラオキソ-8-(プロパン-2-イル)-1,4,7,10-テトラアザシクロドデカン-2-イル]酢酸
- シレンジチド
- シクロ(L-Arg-L-αAsp-D-Phe-N-メチル-L-Val-)