H-ARG-GLY-ASP-SER-OH
H-ARG-GLY-ASP-SER-OH 物理性質(zhì)
- 融點(diǎn) :
- 183-187℃
- 比重(密度) :
- 1.65±0.1 g/cm3(Predicted)
- 貯蔵溫度 :
- -20°C
- 溶解性:
- ≥21.65 mg/mL in H2O; insoluble in EtOH; insoluble in DMSO
- 酸解離定數(shù)(Pka):
- 2.84±0.10(Predicted)
- 外見(jiàn) :
- 白色からオフホワイトの粉末
- 色:
- White to off-white
- 由來(lái)生物:
- synthetic
- 水溶解度 :
- 1mg/mlで水に溶ける
- シーケンス:
- H-Arg-Gly-Asp-Ser-OH
- InChIKey:
- NNRFRJQMBSBXGO-CIUDSAMLSA-N
- SMILES:
- N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(O)=O
安全性情報(bào)
- リスクと安全性に関する聲明
- 危険有害性情報(bào)のコード(GHS)
| WGK Germany |
3 |
|
|
| ストレージクラス |
11 - Combustible Solids |
|
|
| 絵表示（GHS） |
|
| 注意喚起語(yǔ) |
警告 |
| 危険有害性情報(bào) |
| コード |
危険有害性情報(bào) |
危険有害性クラス |
區(qū)分 |
注意喚起語(yǔ) |
シンボル |
P コード |
| H302 |
飲み込むと有害 |
急性毒性、経口 |
4 |
警告 |
|
P264, P270, P301+P312, P330, P501 |
| H315 |
皮膚刺激 |
皮膚腐食性/刺激性 |
2 |
警告 |
|
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
強(qiáng)い眼刺激 |
眼に対する重篤な損傷性/眼刺激 性 |
2A |
警告 |
|
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
呼吸器への刺激のおそれ |
特定標(biāo)的臓器毒性、単回暴露； 気道刺激性 |
3 |
警告 |
|
|
|
| 注意書(shū)き |
| P261 |
粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。 |
| P305+P351+P338 |
眼に入った場(chǎng)合：水で數(shù)分間注意深く洗うこと。次にコ ンタクトレンズを著用していて容易に外せる場(chǎng)合は外す こと。その後も洗浄を続けること。 |
|
H-ARG-GLY-ASP-SER-OH 価格
もっと(7)
| メーカー |
製品番號(hào) |
製品説明 |
CAS番號(hào) |
包裝 |
価格 |
更新時(shí)間 |
購(gòu)入 |
|
富士フイルム和光純薬株式會(huì)社(wako)
|
W01BCS4008997 |
H-Arg-Gly-Asp-Ser-OH |
91037-65-9 |
25mg |
￥51000 |
2024-03-01 |
購(gòu)入 |
|
富士フイルム和光純薬株式會(huì)社(wako)
|
W01BCS4008997 |
H-Arg-Gly-Asp-Ser-OH |
91037-65-9 |
100mg |
￥152000 |
2024-03-01 |
購(gòu)入 |
|
Sigma-Aldrich Japan
|
A9041 |
≥95% (HPLC)
Arg-Gly-Asp-Ser ≥95% (HPLC) |
91037-65-9 |
2mg |
￥20700 |
2024-03-01 |
購(gòu)入 |
|
Sigma-Aldrich Japan
|
A9041 |
≥95% (HPLC)
Arg-Gly-Asp-Ser ≥95% (HPLC) |
91037-65-9 |
5mg |
￥23700 |
2024-03-01 |
購(gòu)入 |
|
富士フイルム和光純薬株式會(huì)社(wako)
|
W01TOC3498 |
RGDS peptide |
91037-65-9 |
10mg |
￥57000 |
2024-03-01 |
購(gòu)入 |
H-ARG-GLY-ASP-SER-OH 化學(xué)特性,用途語(yǔ),生産方法
使用
Arg-Gly-Asp-Ser has been used:
- to study its effects on cell attachment in rats
- to analyse the interaction of fibrinogen with erythrocytes occurs through integrin related receptor
- to pretreat the cells, to assess the role of integrin in the cell attachment process
- to test its competition with platelet-secreted, nanosheet-adsorbed proteins for binding to glycoprotein IIIa (GPIIIa)
一般的な説明
The tetrapeptide Arg-Gly-Asp-Ser (RGDS) is a key component of the cell attachment domain of fibronectin. The RGDS sequence was found initially to promote the attachment of rat kidney fibroblasts (NRKcells) to fibronectin and synthetic fibronectin peptides coupled to protein-coated plastic. Further investigation indicated that the free RGDS peptide inhibited the attachment of NRK cells to fibronectin coated substrates. The RGDS sequence has been shown to occur in several other proteins, such as the λ receptor on
E. coli and the Sindbis coat protein. RGDS is also a target sequence for spirochete adherence of the syphilis bacterium Treponema pallidum.
RGDS has been shown to block fibrinogen-induced aggregation of intact erythrocytes and specific binding of fibrinogen to erythrocyte membranes. The effect of RGDS on transforming growth factor 1 (TGF1) mRNA expression and secretion in cultured human mesangial cells has been investigated. RGDS has been utilized in a study of integrin-mediated signal transduction in cultured cells from the sponge Suberites domuncula. RGDS has been demonstrated
to mitigate the binding of
Mycobacterium tuberculosis to murine alveolar macrophages
H-ARG-GLY-ASP-SER-OH 上流と下流の製品情報(bào)
原材料
準(zhǔn)備製品
H-ARG-GLY-ASP-SER-OH 生産企業(yè)
Global( 190)Suppliers
H-ARG-GLY-ASP-SER-OH スペクトルデータ(1HNMR)
91037-65-9(H-ARG-GLY-ASP-SER-OH)キーワード:
- 91037-65-9
- Fibronectin tetrapeptide
- L-Arginylglycyl-L-alpha-aspartyl-L-serine
- L-Serine, L-arginylglycyl-L-alpha-aspartyl-
- L-Serine, N-(N-(N-L-arginylglycyl)-L-alpha-aspartyl)-
- arginyl-glycyl-aspartyl-serine
- RGDS 1/2ACOH 2H2O
- L-Serine,N-[N-(N-L-arginylglycyl)-L-a-aspartyl]-
- L-Serine,L-arginylglycyl-L-a-aspartyl-
- Arg-Gly-Asp-Ser, >=98%
- RGDS PEPTIDE;FIBRONECTIN INHIBITOR
- L-ARG-GLY-ASP-SER
- H-ARG-GLY-ASP-SER-OH
- FIBRONECTIN ATTACHMENT PEPTIDE
- ARG-GLY-ASP-SER
- ARG-GLY-ASP-SER 1/2ACOH 2H2O
- RGDS/ARG-GLY-ASP-SER
- Arg-Gly-Asp-Ser-OH
- L-Arg-Gly-L-Asp-L-Ser-OH
- RGDS peptide
- FIBRONECTIN INHIBITOR
- H-Arg-Gly-Asp-Ser-OH - CAS 91037-65-9 - Calbiochem
- Arg-Gly-Asp-Ser, ≥95%(HPLC)
- L-Serine, L-arginylglycyl-L-α-aspartyl-
- RGDS - 5 mg
- The integrin-blocking peptide
- RGDS peptide (Arg-Gly-Asp-Ser)
- RGDS
- RGDSペプチド
- H-ARG-GLY-ASP-SER-OH