Diethyl 1,3-acetonedicarboxylate
|
|
Diethyl 1,3-acetonedicarboxylate ??
- ???
- 125 °C
- ?? ?
- 250 °C (lit.)
- ??
- 1.113 g/mL at 25 °C (lit.)
- ???
- n
20/D 1.440(lit.)
- ???
- 187 °F
- ?? ??
- Sealed in dry,2-8°C
- ???
- ?????(?? ???), ???????(?? ???)
- ?? ?? (pKa)
- 9.66±0.46(Predicted)
- ??? ??
- ??
- ??
- ??~??? ??
- ???
- 10g/L(20℃)
- ??
- Moisture Sensitive
- BRN
- 640146
- InChI
- 1S/C9H14O5/c1-3-13-8(11)5-7(10)6-9(12)14-4-2/h3-6H2,1-2H3
- InChIKey
- ZSANYRMTSBBUCA-UHFFFAOYSA-N
- SMILES
- CCOC(=O)CC(=O)CC(=O)OCC
- CAS ??????
- 105-50-0(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | F,Xi | ||
|---|---|---|---|
| ?? ???? ?? | 36/37/38 | ||
| ????? | 23-24/25-36-26 | ||
| ????(UN No.) | UN 2810 | ||
| WGK ?? | 3 | ||
| ?? ?? ?? | Flammable/Moisture Sensitive | ||
| TSCA | TSCA listed | ||
| HS ?? | 29183000 | ||
| ???? ??? | 10 - Combustible liquids | ||
| ???? ?? | KE-27626 |
Diethyl 1,3-acetonedicarboxylate C??? ??, ??, ??
??? ??
clear colorless to pale yellow liquid??
Diethyl 1,3-acetonedicarboxylate was used in the synthesis of novel pyrido[4,3,2-de]quinoline, isoquinolino[6,5,4,3-cde] quinoline and pyrazomycin. It was used as starting reagent in the synthesis of (±)-thienamycin, potent β-lactam antibiotic.Pharmaceutical Applications
Azoles, are valuables five membered nitrogen heterocycles, mainly those with 1,2,3-triazoles nucleus. Since they display intriguing pharmacological properties associated with a wide spectrum of biological activities like: anticancer, antiviral, antifungal, anti-acetyl-cholinesterase, anti-inflammatory, antioxidant, antidiabetic and anti-HIV. Diethyl 1,3-acetonedicarboxylate can be used as a raw material for the synthesis of 1,2,3-triazoles.[1]
Diethyl 1,3-acetonedicarboxylate ?? ?? ? ???
???
??-???????
1,1,5,5-????????-1,4-??-3-?
Pentanedioic acid, 3-(carboxymethyl)-3-hydroxy-
Malonyl chloride
?? ??
4, 6-DIHYDROXYNICOTINIC ACID ETHYL ESTER
6-???-4-???????
ETHYL 6-CHLORO-4-ETHOXYPYRIDINE-3-CARBOXYLATE
URACIL-4-ACETIC ACID
4,6-Dichloronicotinic acid
Ethyl 4,6-dichloronicotinate
??(3-)??1,3,5???
??4,6-?????-2-(????????)??????
4,6-dihydroxypyridazine-3-carboxylicacid
3-????????
4,6-????-3-??????
1,5-??????-??-3-?
6-???-1H-????[4,3-c]???
????
Diethyl 1,3-acetonedicarboxylate ?? ??
???( 505)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 |
Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 |
sales1@chuanghaibio.com | China | 5220 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-86-17392712779 +86-13289823923 |
1090@dideu.com | China | 8660 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-18712993135 |
sales01@tairunfaz.com | China | 8051 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-17732866630 |
mina@chuanghaibio.com | China | 18126 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 |
info@dakenam.com | China | 14026 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21585 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2988 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29812 | 58 |