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????? ??? ???
?? ??:
330942-05-7
???:
?????
???(??):
?????
???:
Betrixaban
???(??):
CS-1417;MK-4448;PRT-021;MLN-1021;PRT 054021;Betrixaban;Bertixaban;Betrixaban-d4;Betrixaban, >=98%;Betrixaban USP/EP/BP
CBNumber:
CB02500171
???:
C23H22ClN5O3
??? ??:
451.91
MOL ??:
330942-05-7.mol
MSDS ??:
SDS

????? ??

???
210-213°C
??
1.30±0.1 g/cm3(Predicted)
?? ??
2-8°C
???
DMSO(?? ???), ???(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
11.00±0.70(Predicted)
??
???
InChI
InChI=1S/C23H22ClN5O3/c1-29(2)26-13-15-4-6-16(7-5-15)22(30)27-20-10-9-18(32-3)12-19(20)23(31)28-21-11-8-17(24)14-25-21/h4-14H,1-3H3,(H,27,30)(H,25,28,31)
InChIKey
PGOYJYHMBCZDLN-UHFFFAOYSA-N
SMILES
C(NC1=NC=C(Cl)C=C1)(=O)C1=CC(OC)=CC=C1NC(=O)C1=CC=C(C=NN(C)C)C=C1
CAS ??????
330942-05-7
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
WGK ?? WGK 3
???? ??? 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
STOT RE 2
????(GHS): Exclamation Mark (GHS07)Health Hazard (GHS08)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
H373 ??? ?? ?? ???? ??(??, ??? ?? ??? ?? ??? ??)? ??? ??? ? ?? ?? ???? ?? - ?? ?? ?? 2 ?? P260, P314, P501
??????:
P314 ???? ??? ???? ??·??? ????.
NFPA 704
0
2 0

????? C??? ??, ??, ??

??

Betrixaban is a novel anticoagulant, an oral direct inhibitor of factor Xa (FXa) for use in the prevention of venous thromboembolism (VTE).

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