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(S)-N-[2-[2,3-Dihydro-6-hydroxy-7-(2-hydroxyethyl)-1H-inden-1-yl]ethyl]propanamide

(S)-N-[2-[2,3-Dihydro-6-hydroxy-7-(2-hydroxyethyl)-1H-inden-1-yl]ethyl]propanamide ??? ???
?? ??:
196597-88-3
???:
(S)-N-[2-[2,3-Dihydro-6-hydroxy-7-(2-hydroxyethyl)-1H-inden-1-yl]ethyl]propanamide
???(??):
Ramelteon Diol Impurity;N-[2-[(1S)-2,3-Dihydro-6-hydroxy-7-(2-hydroxyethyl)-1H-inden-1-yl]ethyl]propanaMid;(S)-N-[2-(6-Hydroxy-7-(2-hydroxyethyl)-2,3-dihydro-1H-iden-1-yl)ethyl]propionaMide;(S)-N-[2-[2,3-Dihydro-6-hydroxy-7-(2-hydroxyethyl)-1H-inden-1-yl]ethyl]propanamide;Propanamide, N-[2-[(1S)-2,3-dihydro-6-hydroxy-7-(2-hydroxyethyl)-1H-inden-1-yl]ethyl]-
CBNumber:
CB02508364
???:
C16H23NO3
??? ??:
277.36
MOL ??:
196597-88-3.mol

(S)-N-[2-[2,3-Dihydro-6-hydroxy-7-(2-hydroxyethyl)-1H-inden-1-yl]ethyl]propanamide ??

???
144-146 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
?? ?
512.4±50.0 °C(Predicted)
??
1.154±0.06 g/cm3(Predicted)
?? ??
Hygroscopic, Refrigerator, under inert atmosphere
???
DMSO(?? ???), ???(?? ???), ???(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
10.46±0.40(Predicted)
??
???? ?? ?????

??

(S)-N-[2-[2,3-Dihydro-6-hydroxy-7-(2-hydroxyethyl)-1H-inden-1-yl]ethyl]propanamide C??? ??, ??, ??

??? ??

Pale-Brown Solid

??

Intermediate in the production of Ramelteon.

(S)-N-[2-[2,3-Dihydro-6-hydroxy-7-(2-hydroxyethyl)-1H-inden-1-yl]ethyl]propanamide ?? ?? ? ???

???

?? ??


(S)-N-[2-[2,3-Dihydro-6-hydroxy-7-(2-hydroxyethyl)-1H-inden-1-yl]ethyl]propanamide ?? ??

???( 13)?? ??
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