Oxyclozanide
Oxyclozanide ??
???
77-81C
?? ?
215C
??
1.6274 (rough estimate)
???
1.6200 (estimate)
?? ??
Sealed in dry,Room Temperature
???
DMSO(?? ???), ???(?? ???)
?? ?? (pKa)
5.07±0.50(Predicted)
??? ??
Solid
??
White to off-white
???
29mg/L(25℃)
?? ??
??? ? ???
InChI
InChI=1S/C13H6Cl5NO3/c14-4-1-6(16)11(20)8(2-4)19-13(22)9-10(18)5(15)3-7(17)12(9)21/h1-3,20-21H,(H,19,22)
InChIKey
JYWIYHUXVMAGLG-UHFFFAOYSA-N
SMILES
C(NC1=CC(Cl)=CC(Cl)=C1O)(=O)C1=C(O)C(Cl)=CC(Cl)=C1Cl
CAS ??????
2277-92-1(CAS DataBase Reference)
??
?? ? ?? ??
?? ? ???? ?? (GHS)
??? ??
Xn;N,N,Xn,Xi
?? ???? ??
22-50/53-36/37/38
?????
60-61-36-26
????(UN No.)
UN 3077
WGK ??
3
RTECS ??
CV8576000
???? ???
11 - Combustible Solids
Hazard Classifications
Acute Tox. 4 Oral
????(GHS):
?? ?:
Warning
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??·?? ??
?? ??
??
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P- ??
H302 ??? ???
?? ?? ?? - ??
?? 4
??
P264, P270, P301+P312, P330, P501
H410 ??? ??? ?? ????? ?? ???
?? ????? ?? - ??
?? 1
??
P273, P391, P501
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P273 ???? ???? ???.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P391 ???? ????.
P501 ...? ??? / ??? ?? ???.
Oxyclozanide C??? ??, ??, ??
??
Anthelmintic
Synthesis
A preparation method of Oxyclozanide (pentachloroasalamide), which takes 2, 4-dichlorophenol which is easily available in the market as a raw material, and obtains the pentachloroasalamide by nitration, reduction and condensation with 3, 5, 6-trichlorosalicylic acid.
Oxyclozanide ?? ?? ? ???
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Oxyclozanide ?? ??
???( 436)?? ??
Belgium 1
Canada 3
China 250
Colombia 1
Czech Republic 2
Egypt 1
Europe 2
France 1
Germany 7
India 123
Japan 2
South Korea 1
Switzerland 2
The Netherlands 1
Tunisia 1
United Arab Emirates 1
United Kingdom 7
United States 28
Uruguay 1
Venezuela 1
Global 436
