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N-?????-N-????

N-?????-N-????
N-?????-N-???? ??? ???
?? ??:
924-16-3
???:
N-?????-N-????
???(??):
?????????;N-??????-N-????;N-?????-N-????;N-??????-N-????(N-NITROSODI-N-BUTYLAMINE);N-?????????
???:
N-Nitrosodibutylamine
???(??):
NDBA;N-NITROSO-DI-N-BUTYLAMINE;DBNA;Dibutylnitrosoamine;N,N-dibutylnitrous amide;N56-003;NSC 6830;Butylnitrosamine;N-Nitroso-di-aMine;rcrawastenumberu172
CBNumber:
CB0358200
???:
C8H18N2O
??? ??:
158.24
MOL ??:
924-16-3.mol
MSDS ??:
SDS

N-?????-N-???? ??

???
<25℃
?? ?
237 °C
??
0,9 g/cm3
???
1.4485 (589.3 nm 20℃)
?? ??
-20°C Freezer
???
???(?? ???), ?????(?? ???), ???????(?? ???), ???(?? ???)
??? ??
Liquid
?? ?? (pKa)
-3.14±0.70(Predicted)
??
?? ??~???
???
1.199g/L(??)
Henry's Law Constant
7.2×10-1 mol/(m3Pa) at 25℃, Mirvish et al. (1976)
???
???
?? ??
environmental
InChI
1S/C8H18N2O/c1-3-5-7-10(9-11)8-6-4-2/h3-8H2,1-2H3
InChIKey
YGJHZCLPZAZIHH-UHFFFAOYSA-N
SMILES
CCCCN(CCCC)N=O
CAS ??????
924-16-3(CAS DataBase Reference)
IARC
2B (Vol. 17, Sup 7) 1987
EPA
N-Nitrosodi-n-butylamine (924-16-3)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn,T
?? ???? ?? 22-40-63-43-36/37/38-23/24/25-46-45
????? 45-36/37-24/25-23-53
????(UN No.) 2810
WGK ?? 3
RTECS ?? EJ4025000
TSCA TSCA listed
HS ?? 2928.00.5000
?? ?? 6.1(b)
???? III
???? ??? 10 - Combustible liquids
Hazard Classifications Acute Tox. 4 Oral
Carc. 2
?? ?? ??? 924-16-3(Hazardous Substances Data)
????(GHS): Exclamation Mark (GHS07)Health Hazard (GHS08)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
H351 ?? ??? ??? ??? (????? ?? ???? ???? ???? ??? ?? ????? ??? ???? ??) ??? ?? ?? 2 ?? P201, P202, P281, P308+P313, P405,P501
??????:
P202 ?? ?? ?? ??? ?? ???? ??? ???? ???.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P280 ????/???/???/?????? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P308+P313 ?? ?? ??? ???? ???? ??· ??? ????.
NFPA 704
0
2 0

N-?????-N-???? C??? ??, ??, ??

??? ??

N-Nitrosodi-n-butylamine is a yellow, oily liquid.

??

N-Nitrosodi-n-butylamine is used primarily as a research chemical (IARC 1974). It has also been used as an intermediate in the synthesis of di-n-butylhydrazine.

?? ??

Pale yellow liquid.

?? ???

N-NITROSODIBUTYLAMINE is a nitrated amine derivative. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

????

Inhalation of material may be harmful. Contact may cause burns to skin and eyes. Inhalation of Asbestos dust may have a damaging effect on the lungs. Fire may produce irritating, corrosive and/or toxic gases. Some liquids produce vapors that may cause dizziness or suffocation. Runoff from fire control may cause pollution.

????

Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, tumorigenic, and neoplastigenic data. Moderately toxic by ingestion, subcutaneous, and intraperitoneal routes. Experimental teratogenic effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NITROSAMINES.

??? ??

N-Nitrosodi-n-butylamine is a carcinogenic nitrosamine. It is found or used in various manufacturing industries, including chemical, rubber, metal, etc., and in research.

Carcinogenicity

N-Nitrosodi-n-butylamine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

?? ??

UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3082 Environmentally hazardous substances, liquid, n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required

? ???

N-Nitrosodi-n-butylamine is light sensitive. Nitrosamines can be strong oxidizers; contact with these materials may cause fires or explosions. Keep away from combustible materials, alkaline materials, strong acids, strong bases. Nitrated organics range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction. Amines are a chemical base: will neutralize acids to form salts plus water with an exothermic reaction. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents such as hydrides, nitrides, alkali metals, and sulfides.

??? ??

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Under 40 CFR 261.5 small quantity generators of this waste may qualify for partial exclusion from hazardous waste regulations.

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