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Dibenzyl azodicarboxylate

Dibenzyl azodicarboxylate ??? ???
?? ??:
2449-05-0
???:
Dibenzyl azodicarboxylate
???(??):
DBAD;Dibenzyl diazene-1,2-dicarboxylate;DZAD;(E)-dibenzyl diazene-1,2-dicarboxylate;Dibenzyl azodicarbox;Minocycline Impurity 49;DIBENZYL AZODICARBOXYLATE;Dibenzy| azodicarbo×ylate;Dibenzylazodicarboxylate,98%;Bis(benzyloxycarbonyl)diazene
CBNumber:
CB0493918
???:
C16H14N2O4
??? ??:
298.29
MOL ??:
2449-05-0.mol
MSDS ??:
SDS

Dibenzyl azodicarboxylate ??

???
43-47 °C (lit.)
?? ?
439.72°C (rough estimate)
??
1.2028 (rough estimate)
???
1.6240 (estimate)
???
>230 °F
?? ??
2-8°C
??? ??
??? ??
??
????? ?????
??
Light Sensitive
BRN
2298734
InChI
InChI=1S/C16H14N2O4/c19-15(21-11-13-7-3-1-4-8-13)17-18-16(20)22-12-14-9-5-2-6-10-14/h1-10H,11-12H2
InChIKey
IRJKSAIGIYODAN-ISLYRVAYSA-N
SMILES
N(C(OCC1=CC=CC=C1)=O)=NC(OCC1=CC=CC=C1)=O
CAS ??????
2449-05-0(CAS DataBase Reference)
EPA
Diazenedicarboxylic acid, bis(phenylmethyl) ester (2449-05-0)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi,F
?? ???? ?? 36/37/38-11
????? 26-37/39-16
????(UN No.) 3224
WGK ?? 3
TSCA TSCA listed
HS ?? 29270000
???? ??? 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
???? ?? KE-09865
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
2
2 0

Dibenzyl azodicarboxylate MSDS


Dibenzyl azodicarboxylate

Dibenzyl azodicarboxylate C??? ??, ??, ??

??? ??

yellow to orange crystalline powder

??

Dibenzyl azodicarboxylate is a reagent used in the synthesis of Minocycline-d6 (M344797). Minocycline-d6 is a labeled second generation tetracycline antibiotic. Antibacterial.

?? ??

Dibenzyl azodicarboxylate undergoes[4+2] cycloaddition reaction with glycal to yield 2-aminoglycosides.

Synthesis

PIDA (phenyliodine diacetate) and DCM (dichloromethane) were added to compound dibenzyl hydrazine-1,2-dicarboxylate, and the mixture was reacted with stirring at room temperature for 30 minutes to obtain DBAD (dibenzyl azodicarboxylate) in a yield of 97%.Dibenzyl azodicarboxylate

Dibenzyl azodicarboxylate ?? ?? ? ???

???

?? ??


Dibenzyl azodicarboxylate ?? ??

???( 281)?? ??
??? ?? ??? ?? ?? ? ??
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Dibenzyl azodicarboxylate ?? ??:

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