Tetraisopropyl methylenediphosphonate
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Tetraisopropyl methylenediphosphonate ??
- ?? ?
- 155 °C/0.5 mmHg (lit.)
- ??
- 1.08 g/mL at 25 °C (lit.)
- ???
- 0.017Pa at 20℃
- ???
- n
20/D 1.431(lit.)
- ???
- 320 °F
- ?? ??
- -20°C
- ???
- ?????(?? ???), ???(?? ???)
- ??? ??
- liquid
- ??
- ??~???? ??
- Specific Gravity
- 1.080
- ???
- ?? ???.
- BRN
- 1080180
- InChI
- 1S/C13H30O6P2/c1-10(2)16-20(14,17-11(3)4)9-21(15,18-12(5)6)19-13(7)8/h10-13H,9H2,1-8H3
- InChIKey
- FKHXXJRKGVDPQP-UHFFFAOYSA-N
- SMILES
- CC(C)OP(=O)(CP(=O)(OC(C)C)OC(C)C)OC(C)C
- LogP
- 1.3 at 20℃
- CAS ??????
- 1660-95-3(CAS DataBase Reference)
Tetraisopropyl methylenediphosphonate C??? ??, ??, ??
??? ??
Clear colorless to slightly yellow liquid??
Tetraisopropyl Methylenediphosphonate is used in the preparation of E2-bisphosphonate conjugates as potential anti-osteoporosis agents. Also used in the preparation of AZT 5’-Triphosphate compounds which display inhibitory effects on HIV-1 reverse transcrpitase.?? ??
Tetraisopropyl methylenediphosphonate (IPCP) is a tetraisopropyl ester of methylenediphosphonic acid. It is an electroneutral ligand, reported to be synthesized from triisopropyl phosphate. Powder electron paramagnetic resonance (EPR) studies of tris complexes of Cu(II) complexes with IPCP has been analyzed.Tetraisopropyl methylenediphosphonate ?? ?? ? ???
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1-METHYLETHYLPHOSPHONICACIDBIS(1-METHYLETHYL)ESTER
Phosphorous acid, bis(1-methylethyl) ester
TRIISOPROPYL PHOSPHATE
?? ??
Tetraisopropyl methylenediphosphonate ?? ??
???( 253)?? ??
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Tetraisopropyl methylenediphosphonate ?? ??:
?????????????? ???????? ??????????? ??????????? ?????-2-??????????? ????????? ???(IV) ??????? ?????? ? ????? ????????
TETRAISOPROPYL 1,2-ETHYLENEDIPHOSPHONATE
TETRAISOPROPYL ORTHOSILICATE
Methylene dithiocyanate
Methanedisulphonic acid
methanedisulphonyl dichloride
TETRAMETHYL METHYLENEDIPHOSPHONATE
N,N-Dimethylallylamine
ALLYL METHYL ETHER
2-METHYLPENTANE