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1166-52-5
???:
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???(??):
?????;?????;???????;?????;??? ????
???:
Dodecyl gallate
???(??):
LAURYL GALLATE;E312;96-97℃;3mg/kg;progallinla;Progallin LA;nipagallinla;dodecyl3,4,5-;Nipagallin LA;auryl gallate
CBNumber:
CB1159943
???:
C19H30O5
??? ??:
338.44
MOL ??:
1166-52-5.mol
MSDS ??:
SDS

??? ???? ??

???
94-97 °C (lit.)
?? ?
394.57°C (rough estimate)
??
1.0677 (rough estimate)
???
1.6120 (estimate)
?? ??
Store below +30°C.
???
?? ?? ?? ??? ?? ?? ???, ???(96%)? ? ??, ?????? ?? ????.
??? ??
Solid
?? ?? (pKa)
7.93±0.25(Predicted)
??
???? ?? ??
??
100.00%. ?? ??
???
????? ???
??
Air Sensitive
BRN
2701981
?? ??
????
???
?? ? ??
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??? ?? ??
????
InChI
1S/C19H30O5/c1-2-3-4-5-6-7-8-9-10-11-12-24-19(23)15-13-16(20)18(22)17(21)14-15/h13-14,20-22H,2-12H2,1H3
InChIKey
RPWFJAMTCNSJKK-UHFFFAOYSA-N
SMILES
CCCCCCCCCCCCOC(=O)c1cc(O)c(O)c(O)c1
LogP
6.365 (est)
CAS ??????
1166-52-5(CAS DataBase Reference)
NIST
Gallic acid, n-dodecyl ester(1166-52-5)
EPA
Benzoic acid, 3,4,5-trihydroxy-, dodecyl ester (1166-52-5)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 43
????? 24-37
????(UN No.) 3335
WGK ?? 1
RTECS ?? DH9100000
TSCA TSCA listed
HS ?? 29182950
???? ??? 13 - Non Combustible Solids
Hazard Classifications Skin Sens. 1
?? LD50 orally in Rabbit: 5000 mg/kg
???? ?? KE-34288
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H317 ????? ?? ??? ??? ? ?? ?? ??? ?? ?? 1 ?? P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
??????:
P280 ????/???/???/?????? ?????.
NFPA 704
0
2 0

??? ???? MSDS


Dodecyl 3,4,5-trihydroxybenzoate

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This gallate ester (E 310) is an antioxidant added to foods and cosmetics to prevent oxidation of unsaturated fatty acids. Cases have been reported in workers in the food industry, gallate being contained in margarine. It is also present in washing powder.

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white to cream powder

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Dodecyl Gallate is an antioxidant used in cream cheese, instant mashed potatoes, margarine, fats, and oils.

?? ??

Lauryl gallate is a major monomer flavanol found in green tea and shows antioxidant activity in polymers.

???? ??

Dodecyl gallate exhibits both potent chain-breaking and preventive antioxidant activity. The pyrogallol moiety is responsible for both activities. Dodecyl (lauryl) gallate prevents generation of superoxide radicals by xanthine oxidase, and this activity comes from its ability to inhibit the enzyme[1].

?? ?? ??

This gallic acid ester (E 310) is an antioxidant added to food and cosmetics to prevent oxidation of unsaturated fatty acids. Cases were reported in workers of the food industry, gallate being contained in margarine, and from washing powder.

Safety Profile

Poison by ingestion and inhalation. Moderately toxic by skin contact. A severe eye irritant. Questionable carcinogen with experimental tumorigenic data. A pesticide. When heated to decomposition it emits very toxic fumes of NOx.

Carcinogenicity

In a 2-year feeding study, with the administration of up to 5 mg/kg of feed to rats, no increase in tumor incidence was noted . In female mice, a dermal injection of dodecyl gallate (100 nmol in 0.2mL acetone) inhibits the formation of skin carcinomas and papillomas induced by the tumor promoter phorbol myristate and the initiator 7,12-dimethylbenz[a]anthracene .

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