LY 294002 Hydrochloride
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LY 294002 Hydrochloride ??
- ???
- 183-185℃
- ?? ?
- 494.6±45.0 °C(Predicted)
- ??
- 1.266
- ?? ??
- Sealed in dry,Store in freezer, under -20°C
- ???
- DMSO: >5mg/mL
- ??? ??
- ??
- ??? ??
- ??? ??
- ?? ?? (pKa)
- 0.55±0.20(Predicted)
- ??
- ???? ?????
- ???
- 5mg/ml? DMSO? ?????. ?? ???
- ???
- ??? ?? ?????? 1? ?? ??????. DMSO? ???? -20°?? ?? 4?? ?? ??? ? ????.
- InChI
- InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2
- InChIKey
- CZQHHVNHHHRRDU-UHFFFAOYSA-N
- SMILES
- C1(N2CCOCC2)OC2=C(C3=CC=CC=C3)C=CC=C2C(=O)C=1
- CAS ??????
- 154447-36-6
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ????? | 24-25 | ||
|---|---|---|---|
| WGK ?? | 3 | ||
| HS ?? | 29349990 | ||
| ???? ??? | 10 - Combustible liquids |
| ????(GHS): |
 
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| ?? ?: | Danger | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| ??·?? ??: |
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LY 294002 Hydrochloride C??? ??, ??, ??
??
LY294002 is a selective phosphatidylinositol 3-??
A potent blocker of PI 3-kinase/Akt signaling.??
ChEBI: LY294002 is a chromone substituted with a phenyl group at position 8 and a morpholine group at position 2. It has a role as an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor, an autophagy inhibitor and a geroprotector. It is a member of chromones, a member of morpholines and an organochlorine compound.???? ??
A highly selective inhibitor of phosphatidylinositol 3-kinase (IC 50 values are 0.31, 0.73, 1.06 and 6.60 μ M for PI3K β , PI3K α , PI3K δ and PI3K γ respectively). Inhibits proliferation and induces apoptosis in human colon cancer cells in vitro and in vivo .LY 294002 Hydrochloride ?? ?? ? ???
???
4H-1-Benzopyran-4-one, 8-hydroxy-2-(4-morpholinyl)-
1-(2-hydroxybiphenyl-3-yl)-3-morpholinopropane-1,3-dione
???????
??????-?????2-????-4-?-4-??-4H-???-8-?????
??2-?????-3-??-?????
methyl 2,3-dihydroxybenzoate
??3-?????????
2,3-Dihydroxybenzoic acid
2-????3-??????
????
?? ??
LY 294002 Hydrochloride ?? ??
???( 406)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 |
sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 |
info@dakenam.com | China | 14014 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29815 | 58 |
| Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 965 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49979 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 |
marketing@targetmol.com | United States | 32466 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6312 | 58 |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 |
mcbio_sales@163.com | China | 2251 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 28509 | 58 |
LY 294002 Hydrochloride ?? ??:
????????? ???????
Ribonucleic acid
1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol
Acetylcholine
LY-364947
LY 88074
(S)-3-fluoro-4-(4-((2-(3-fluorophenyl)pyrrolidin-1-yl)methyl)phenoxy)benzamide
Cyclo[Phe-Tyr-Lys(iPr)-D-Arg-2-Nal-Gly-D-Glu]-Lys(iPr)-NH2
DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS*
LY2409881 trihydrochloride
LY 2784544
LY2584702
LY3214996
2-(4-((4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)oxy)pyridin-2-yl)amino)pyridin-2-yl)propan-2-ol
Etalocib
LY2228820
LY-2562175
LY2828360