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????

????
???? ??? ???
?? ??:
6804-07-5
???:
????
???(??):
????;????(CARBADOX)
???:
Carbadox
???(??):
CBX;M31;MOD1;gs6244;CARBADO;Mecadox;p25beta;CARBADOX;fortigro;getroxel
CBNumber:
CB1425347
???:
C11H10N4O4
??? ??:
262.22
MOL ??:
6804-07-5.mol
MSDS ??:
SDS

???? ??

???
239-240°C
?? ?
405.47°C (rough estimate)
??
1.3602 (rough estimate)
???
1.6000 (estimate)
???
18°(64°F)
?? ??
2-8°C
???
DMSO(?? ??? ??)
??? ??
??
?? ?? (pKa)
10.51±0.46(Predicted)
??
????? ?? ?????
???
1N NaOH(50mg/ml) ? ?(??)? ?????.
Henry's Law Constant
2.2×1017 mol/(m3Pa) at 25℃, HSDB (2015)
???
???
InChI
1S/C11H10N4O4/c1-19-11(16)13-12-6-8-7-14(17)9-4-2-3-5-10(9)15(8)18/h2-7H,1H3,(H,13,16)/b12-6+
InChIKey
OVGGLBAWFMIPPY-WUXMJOGZSA-N
SMILES
COC(=O)N\N=C\c1cn(=O)c2ccccc2n1=O
CAS ??????
6804-07-5
EPA
Hydrazinecarboxylic acid, 2-[(1,4-dioxido-2-quinoxalinyl)methylene]-, methyl ester (6804-07-5)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? F,T
?? ???? ?? 45-11-22
????? 53-45
????(UN No.) UN 1325 4.1/PG 2
WGK ?? 3
RTECS ?? FE2779000
?? ?? 4.1
HS ?? 29339900
???? ??? 4.1B - Flammable solid hazardous materials
Hazard Classifications Acute Tox. 4 Oral
Carc. 1B
Flam. Sol. 1
?? ?? ??? 6804-07-5(Hazardous Substances Data)
???? ?? KE-05-0711
????(GHS): Flame (GHS02)Exclamation Mark (GHS07)Health Hazard (GHS08)
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H228 ??? ?? ??? ?? ?? 1
?? 2
??
??
P210, P240,P241, P280, P370+P378
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
H350 ?? ??? ? ?? (????? ?? ???? ???? ???? ??? ?? ????? ??? ???? ??) ??? ?? ?? 1A, 1B ??
??????:
P201 ?? ? ?? ???? ?????.
P210 ?·???·??·????? ????? - ?? ???.
P240 ??? ????? ?? ? ??????.
P280 ????/???/???/?????? ?????.
P405 ???? ?????.
NFPA 704
0
2 0

???? MSDS


Carbadox

???? C??? ??, ??, ??

??? ??

Yellow Crystalline Solid

??

Carbadox has been used to suppress aldosterone production, to study the spread of shiga toxin-producing Escherichia coli (STEC) strains, and to compare different antimicrobial activities. Carbadox is a quinoxaline-di-N-oxide antibiotic that is generally used in feed to swine to prevent dysentery and improve feed efficiency. It inhibits bacteria by intercalation and induction of mutations in bacterial genome.

Safety Profile

Moderately toxic by ingestion. Questionable carcinogen with experimental carcinogenic effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of Nox.

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???( 160)?? ??
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