????
|
|
???? ??
- ???
- 108-9°C
- ?? ?
- 396.7±31.0 °C(Predicted)
- ??
- 1.16±0.1 g/cm3(Predicted)
- ???
- ?????(?? ???), ???(?? ???), ?(?? ???)
- ??? ??
- ??
- ??? ??
- ??? ??
- ?? ?? (pKa)
- 9.47±0.20(Predicted)
- ??
- ?? ??
- InChI
- InChI=1S/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12-,13-,15+/m0/s1
- InChIKey
- ZSBXGIUJOOQZMP-PWNZVWSESA-N
- SMILES
- O=C1CCC[C@]2([H])N1C[C@]1([H])CCCN3CCC[C@]2([H])[C@@]13[H]
- CAS ??????
- 83148-91-8
??
???? C??? ??, ??, ??
??
One of a number of minor alkaloids isolated from Leontice albertii Rgl., this base crystallizes from petroleum ether as colourless prisms. It is dextrorotatory having a specific rotation of [α]D + 59.3° (c 1.3, EtOH) and yields a crystalline methiodide, m.p. 249°C. The structure has been assigned on the basis of chemical analysis and spectroscopic determinations.??
(+)-Sophoridine acts as an anti-inflammatory agent in vitro and in vivo. Anticancer agent, with a promising anti-tumor effect and lower toxicity.?? ??
Kamalitdinov, Iskandarov, Yunusov, Khim. Prir. Soedin., 3, 352 (1967)Kamalitdinov, Iskandarov, Yunusov, ibid, 5,409 (1969)
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???( 79)?? ??
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