??4-????-7-??-1,8-?????-3-???????
??4-????-7-??-1,8-?????-3-??????? ??? ???
?? ??:
13250-96-9
???:
??4-????-7-??-1,8-?????-3-???????
???(??):
??4-????-7-??-1,8-?????-3-???????
???:
ethyl 4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxylate
???(??):
Einecs 236-234-7;Nalidixic Acid EP Impurity B;ethyl 7-methyl-4-oxo-1H-1,8-naphthyridine-3-carboxylate;ethyl 4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxylate;7-methyl-4-oxo-1H-1,8-naphthyridine-3-carboxylic acid ethyl ester;4-Hydroxy-7-methyl-1,8-naphthyridine-3-carboxylic acid ethyl ester;4-hydroxy-7-methyl-1,8-naphthalenedine-3-carboxylic acidethyl ester;1,8-Naphthyridine-3-carboxylic acid, 4-hydroxy-7-methyl-, ethyl ester
CBNumber:
CB1887002
???:
C12H12N2O3
??? ??:
232.24
MOL ??:
13250-96-9.mol
MSDS ??:
SDS
??4-????-7-??-1,8-?????-3-??????? ??
???
272-273 °C
?? ?
350.5±37.0 °C(Predicted)
??
1.296±0.06 g/cm3(Predicted)
?? ??
2-8°C, stored under nitrogen
?? ?? (pKa)
2.83±0.50(Predicted)
??
Yellow to brown Solid
InChI
InChI=1S/C12H12N2O3/c1-3-17-12(16)9-6-13-11-8(10(9)15)5-4-7(2)14-11/h4-6H,3H2,1-2H3,(H,13,14,15)
InChIKey
KPXWNJGVBKCXKB-UHFFFAOYSA-N
SMILES
N1C2C(=CC=C(C)N=2)C(O)=C(C(OCC)=O)C=1
??
??4-????-7-??-1,8-?????-3-??????? C??? ??, ??, ??
??
Ethyl 4-Hydroxy-7-methyl-1,8-naphthyridine-3-carboxylate is a reagent used in the synthesis of flavoquinolones which may display antibacterial activity
Synthesis Reference(s)
Journal of the American Chemical Society, 70, p. 3348, 1948
DOI: 10.1021/ja01190a038
??4-????-7-??-1,8-?????-3-??????? ?? ?? ? ???
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?? ??
??4-????-7-??-1,8-?????-3-??????? ?? ??
???( 23)?? ??
China 18
India 1
The Netherlands 1
United States 3
Global 23
??4-????-7-??-1,8-?????-3-??????? ?? ??:
